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Protein
Submitted name:

Suppressor of cytokine signaling 6

Gene

SOCS6

Organism
Pan troglodytes (Chimpanzee)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Pathwayi: protein ubiquitination

This protein is involved in the pathway protein ubiquitination, which is part of Protein modification.SAAS annotation
View all proteins of this organism that are known to be involved in the pathway protein ubiquitination and in Protein modification.

GO - Biological processi

Enzyme and pathway databases

UniPathwayiUPA00143

Names & Taxonomyi

Protein namesi
Submitted name:
Suppressor of cytokine signaling 6Imported
Gene namesi
Name:SOCS6Imported
OrganismiPan troglodytes (Chimpanzee)Imported
Taxonomic identifieri9598 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaePan

Subcellular locationi

Expressioni

Gene expression databases

BgeeiENSPTRG00000010105

Interactioni

Protein-protein interaction databases

STRINGi9598.ENSPTRP00000017168

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini384 – 491SH2InterPro annotationAdd BLAST108
Domaini486 – 535SOCS boxInterPro annotationAdd BLAST50

Keywords - Domaini

SH2 domainPROSITE-ProRule annotation

Phylogenomic databases

eggNOGiKOG4566 Eukaryota
ENOG4111V4J LUCA
OrthoDBiEOG091G0EP6
TreeFamiTF321368

Family and domain databases

CDDicd10387 SH2_SOCS6, 1 hit
cd03740 SOCS_SOCS6, 1 hit
Gene3Di3.30.505.10, 1 hit
InterProiView protein in InterPro
IPR000980 SH2
IPR036860 SH2_dom_sf
IPR028421 SOCS6
IPR035865 SOCS6_SH2
IPR037345 SOCS6_SOCS
IPR001496 SOCS_box
IPR036036 SOCS_box-like_dom_sf
PANTHERiPTHR44562 PTHR44562, 1 hit
PfamiView protein in Pfam
PF00017 SH2, 1 hit
PF07525 SOCS_box, 1 hit
SMARTiView protein in SMART
SM00252 SH2, 1 hit
SM00253 SOCS, 1 hit
SM00969 SOCS_box, 1 hit
SUPFAMiSSF158235 SSF158235, 1 hit
SSF55550 SSF55550, 1 hit
PROSITEiView protein in PROSITE
PS50001 SH2, 1 hit
PS50225 SOCS, 1 hit

Sequencei

Sequence statusi: Complete.

K7C544-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKKISLKTLR KSFNLNKSKE ETDFMVVQQP SLASDFGKDD SLFGSCYGKD
60 70 80 90 100
MASCDINGED EKGGKNRSKS ESLMGTLKRR LSAKQKSKGK AGTPSGSSAD
110 120 130 140 150
EDTFSSSSAP IVFKDVRAQR PIRSTSLRSH HYSPTPWPLR PTNSEETCIK
160 170 180 190 200
MEVRVKALVH SSSPSPALNG VRKDFHDLQS ETTCQEQANS LKSSASHNGD
210 220 230 240 250
LRLHLDEHVP VVIGLMPQDY IQYTVPLDEG MYPLEGSRSY CLDSSSPMEV
260 270 280 290 300
SAVPPQVGGR AFPEDESQVD QDLVVAPEIF VDQSVNGLLI GTTGVMLQSP
310 320 330 340 350
RAGHDDVPPL SPLLPPMQNN QIQRNFSGLT GTEAHVAESM RCHLNFDPNS
360 370 380 390 400
APGVARVYDS VQSSGPMVVT SLTEELKKLA KQGWYWGPIT RWEAEGKLAN
410 420 430 440 450
VPDGSFLVRD SSDDRYLLSL SFRSHGKTLH TRIEHSNGRF SFYEQPDVEG
460 470 480 490 500
HTSIVDLIEH SIRDSENGAF CYSRSRLPGS ATYPVRLTNP VSRFMQVRSL
510 520 530
QYLCRFVIRQ YTRIDLIQKL PLPNKMKDYL QEKHY
Length:535
Mass (Da):59,577
Last modified:February 28, 2018 - v1
Checksum:i995C2C496B5920C7
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
GABC01001070 mRNA Translation: JAA10268.1
GABF01002780 mRNA Translation: JAA19365.1

Similar proteinsi

Entry informationi

Entry nameiK7C544_PANTR
AccessioniPrimary (citable) accession number: K7C544
Entry historyiIntegrated into UniProtKB/TrEMBL: February 28, 2018
Last sequence update: February 28, 2018
Last modified: April 25, 2018
This is version 3 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

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