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Protein
Submitted name:

TNF receptor-associated factor 4

Gene

TRAF4

Organism
Pan troglodytes (Chimpanzee)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri102 – 154TRAF-typePROSITE-ProRule annotationAdd BLAST53
Zinc fingeri155 – 208TRAF-typePROSITE-ProRule annotationAdd BLAST54
Zinc fingeri209 – 266TRAF-typePROSITE-ProRule annotationAdd BLAST58

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionReceptorImported
LigandMetal-binding, Zinc

Names & Taxonomyi

Protein namesi
Submitted name:
TNF receptor-associated factor 4Imported
Submitted name:
TRAF4 isoform 1Imported
Gene namesi
Name:TRAF4Imported
ORF Names:CK820_G0028454Imported
OrganismiPan troglodytes (Chimpanzee)Imported
Taxonomic identifieri9598 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaePan
Proteomesi
  • UP000002277 Componenti: Chromosome 17

Organism-specific databases

VGNCiVGNC:9737 TRAF4

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Expressioni

Gene expression databases

BgeeiENSPTRG00000008936

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

STRINGi9598.ENSPTRP00000015252

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini18 – 58RING-typeInterPro annotationAdd BLAST41
Domaini102 – 154TRAF-typeInterPro annotationAdd BLAST53
Domaini155 – 208TRAF-typeInterPro annotationAdd BLAST54
Domaini209 – 266TRAF-typeInterPro annotationAdd BLAST58
Domaini307 – 462MATHInterPro annotationAdd BLAST156

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili278 – 305Sequence analysisAdd BLAST28

Zinc finger

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri102 – 154TRAF-typePROSITE-ProRule annotationAdd BLAST53
Zinc fingeri155 – 208TRAF-typePROSITE-ProRule annotationAdd BLAST54
Zinc fingeri209 – 266TRAF-typePROSITE-ProRule annotationAdd BLAST58

Keywords - Domaini

Coiled coilSequence analysis, Zinc-fingerPROSITE-ProRule annotationSAAS annotation

Phylogenomic databases

eggNOGiKOG0297 Eukaryota
ENOG410Z7YX LUCA
GeneTreeiENSGT00550000074359
OMAiCDAGPIA
OrthoDBiEOG091G0GHD
TreeFamiTF321154

Family and domain databases

CDDicd03781 MATH_TRAF4, 1 hit
Gene3Di2.60.210.10, 1 hit
3.30.40.10, 4 hits
InterProiView protein in InterPro
IPR002083 MATH/TRAF_dom
IPR012227 TNF_rcpt--assoc_TRAF
IPR008974 TRAF-like
IPR027138 TRAF4
IPR037307 TRAF4_MATH
IPR018957 Znf_C3HC4_RING-type
IPR001841 Znf_RING
IPR013083 Znf_RING/FYVE/PHD
IPR017907 Znf_RING_CS
IPR001293 Znf_TRAF
PANTHERiPTHR10131:SF118 PTHR10131:SF118, 2 hits
PfamiView protein in Pfam
PF00097 zf-C3HC4, 1 hit
PF02176 zf-TRAF, 2 hits
PIRSFiPIRSF015614 TRAF, 1 hit
SMARTiView protein in SMART
SM00061 MATH, 1 hit
SM00184 RING, 1 hit
SUPFAMiSSF49599 SSF49599, 3 hits
PROSITEiView protein in PROSITE
PS50144 MATH, 1 hit
PS00518 ZF_RING_1, 1 hit
PS50089 ZF_RING_2, 1 hit
PS50145 ZF_TRAF, 3 hits

Sequencei

Sequence statusi: Complete.

K7B4A6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPGFDYKFLE KPKRRLLCPL CGKPMREPVQ VSTCGHRFCD TCLQEFLSEG
60 70 80 90 100
VFKCPEDQLP LDYAKIYPDP ELEVQVLGLP IRCIHSEEGC RWSGPLRHLQ
110 120 130 140 150
GHLNTCSFNV IPCPNRCPMK LSRRDLPAHL QHDCPKRRLK CEFCGCDFSG
160 170 180 190 200
EAYESHEGMC PQESVYCENK CGARMMRRLL AQHATSECPK RTQPCTYCTK
210 220 230 240 250
EFVFDTIQSH QYQCPRLPVA CPNQCGVGTV AREDLPGHLK DSCNTALVLC
260 270 280 290 300
PFKDSGCKHR CPKLAMARHV EESVKPHLAM MCALVSRQRQ ELQELRRELE
310 320 330 340 350
ELSVGSDGVL IWKIGSYGRR LQEAKAKPNL ECFSPAFYTH KYGYKLQVSA
360 370 380 390 400
FLNGNGSGEG THLSLYIRVL PGAFDNLLEW PFARRVTFSL LDQSDPGLAK
410 420 430 440 450
PQHVTETFHP DPNWKNFQKP GTWRGSLDES SLGFGYPKFI SHQDIRKRNY
460 470
VRDDAVFIRA AVELPRKILS
Length:470
Mass (Da):53,543
Last modified:January 9, 2013 - v1
Checksum:iA3F57E0E1081AB88
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AACZ04041502 Genomic DNA No translation available.
GABC01004478 mRNA Translation: JAA06860.1
GABF01009346 mRNA Translation: JAA12799.1
GABD01010265 mRNA Translation: JAA22835.1
GABE01010946 mRNA Translation: JAA33793.1
NBAG03000289 Genomic DNA Translation: PNI46996.1

Genome annotation databases

EnsembliENSPTRT00000016480; ENSPTRP00000015252; ENSPTRG00000008936

Similar proteinsi

Entry informationi

Entry nameiK7B4A6_PANTR
AccessioniPrimary (citable) accession number: K7B4A6
Secondary accession number(s): A0A2J8LIA5, H2QCJ2
Entry historyiIntegrated into UniProtKB/TrEMBL: January 9, 2013
Last sequence update: January 9, 2013
Last modified: May 23, 2018
This is version 44 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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