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Protein

Xylose isomerase

Gene

xylA

Organism
Glaciecola psychrophila 170
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

D-xylopyranose = D-xylulose.UniRule annotationSAAS annotation

Cofactori

Mg2+UniRule annotationNote: Binds 2 magnesium ions per subunit.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei101 – 1011UniRule annotation
Active sitei104 – 1041UniRule annotation
Metal bindingi232 – 2321Magnesium 1UniRule annotation
Metal bindingi268 – 2681Magnesium 1UniRule annotation
Metal bindingi268 – 2681Magnesium 2UniRule annotation
Metal bindingi271 – 2711Magnesium 2UniRule annotation
Metal bindingi296 – 2961Magnesium 1UniRule annotation
Metal bindingi307 – 3071Magnesium 2UniRule annotation
Metal bindingi309 – 3091Magnesium 2UniRule annotation
Metal bindingi339 – 3391Magnesium 1UniRule annotation

GO - Molecular functioni

  1. magnesium ion binding Source: UniProtKB-HAMAP
  2. xylose isomerase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. D-xylose metabolic process Source: UniProtKB-HAMAP
  2. pentose-phosphate shunt Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

IsomeraseUniRule annotation

Keywords - Biological processi

Carbohydrate metabolism, Pentose shuntUniRule annotation, Xylose metabolismUniRule annotation

Keywords - Ligandi

MagnesiumUniRule annotationSAAS annotation, Metal-bindingUniRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Xylose isomeraseUniRule annotation (EC:5.3.1.5UniRule annotation)
Gene namesi
Name:xylAUniRule annotationImported
ORF Names:C427_4907Imported, GPSY_4639Imported
OrganismiGlaciecola psychrophila 170Imported
Taxonomic identifieri1129794 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaAlteromonadalesAlteromonadaceaeGlaciecola
ProteomesiUP000011864: Chromosome

Subcellular locationi

Cytoplasm UniRule annotationSAAS annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

CytoplasmUniRule annotationSAAS annotation

Interactioni

Subunit structurei

Homotetramer.UniRule annotationSAAS annotation

Family & Domainsi

Sequence similaritiesi

Belongs to the xylose isomerase family.UniRule annotation

Phylogenomic databases

KOiK01805.

Family and domain databases

Gene3Di3.20.20.150. 1 hit.
HAMAPiMF_00455. Xylose_isom_A.
InterProiIPR013022. Xyl_isomerase-like_TIM-brl.
IPR013452. Xylose_isom_bac.
IPR001998. Xylose_isomerase.
[Graphical view]
PfamiPF01261. AP_endonuc_2. 1 hit.
[Graphical view]
PRINTSiPR00688. XYLOSISMRASE.
SUPFAMiSSF51658. SSF51658. 1 hit.
TIGRFAMsiTIGR02630. xylose_isom_A. 1 hit.
PROSITEiPS51415. XYLOSE_ISOMERASE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

K7ADC1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTTYFDAIPN IQFEGAESDS PLAFHHYNAN EVVLGKTMSE HLRFAACYWH
60 70 80 90 100
NFCWDGADVF GQGTFNRPWL KPCDPMQMAI QKADVAFEFF SKLNIPYYCF
110 120 130 140 150
HDIDVAPEGD SIHDYVNNFS TMVDVLEQKQ SETGLRLLWG TANLFSNPRF
160 170 180 190 200
AAGGASNPNP DVFSYGATQV FHAMNATKRL GGENYVLWGG REGYESLLNT
210 220 230 240 250
DLRQEREQLG RFFTMVAEHK HKIGFKGALL IEPKPQEPTK HQYDYDTASV
260 270 280 290 300
YGFLKQYGLE QEFKVNIEAN HATLAGHSFH HEIATAISLG IFGSIDANRG
310 320 330 340 350
DPQNGWDTDQ FPTAVDELSL VMYEILKSGG FTTGGLNFDC KLRRQSSDPA
360 370 380 390 400
DLFHGHIGGM DHMALALKKA AAILENDFIA DKLSQRYEGW GQHFGQSILN
410 420 430
GQQNLESLAS HTLSNSLQPK HVSGQQEMME NKVNRVLFG
Length:439
Mass (Da):49,229
Last modified:January 9, 2013 - v1
Checksum:iDEFA1A04110BD272
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP003837 Genomic DNA. Translation: AGH47006.1.
BAES01000095 Genomic DNA. Translation: GAC40242.1.
RefSeqiWP_007643107.1. NZ_BAES01000095.1.
YP_007546354.1. NC_020514.1.

Genome annotation databases

EnsemblBacteriaiAGH47006; AGH47006; C427_4907.
GAC40242; GAC40242; GPSY_4639.
GeneIDi14781622.
KEGGigps:C427_4907.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP003837 Genomic DNA. Translation: AGH47006.1.
BAES01000095 Genomic DNA. Translation: GAC40242.1.
RefSeqiWP_007643107.1. NZ_BAES01000095.1.
YP_007546354.1. NC_020514.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAGH47006; AGH47006; C427_4907.
GAC40242; GAC40242; GPSY_4639.
GeneIDi14781622.
KEGGigps:C427_4907.

Phylogenomic databases

KOiK01805.

Family and domain databases

Gene3Di3.20.20.150. 1 hit.
HAMAPiMF_00455. Xylose_isom_A.
InterProiIPR013022. Xyl_isomerase-like_TIM-brl.
IPR013452. Xylose_isom_bac.
IPR001998. Xylose_isomerase.
[Graphical view]
PfamiPF01261. AP_endonuc_2. 1 hit.
[Graphical view]
PRINTSiPR00688. XYLOSISMRASE.
SUPFAMiSSF51658. SSF51658. 1 hit.
TIGRFAMsiTIGR02630. xylose_isom_A. 1 hit.
PROSITEiPS51415. XYLOSE_ISOMERASE. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. Qin Q.L., Xie B.B., Shu Y.L., Zhang Y.Z.
    Submitted (JAN-2012) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: 170Imported.
  2. "Complete Genome Sequence of Glaciecola psychrophila Strain 170T."
    Yin J., Chen J., Liu G., Yu Y., Song L., Wang X., Qu X.
    Genome Announc. 1:E00199-13(2013) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 170Imported.
  3. "Comparative genomics of the marine bacterial genus Glaciecola reveals the high degree of genomic diversity and genomic characteristic for cold adaptation."
    Qin Q.-L., Xie B.-B., Yu Y., Shu Y.-L., Rong J.-C., Zhang Y.-J., Zhao D.-L., Chen X.-L., Zhang X.-Y., Chen B., Zhou B.-C., Zhang Y.-Z.
    Environ. Microbiol. 16:1642-1653(2014) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: 170Imported.

Entry informationi

Entry nameiK7ADC1_9ALTE
AccessioniPrimary (citable) accession number: K7ADC1
Entry historyi
Integrated into UniProtKB/TrEMBL: January 9, 2013
Last sequence update: January 9, 2013
Last modified: March 4, 2015
This is version 24 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.