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Protein

Phosphoenolpyruvate carboxylase

Gene

ppc

Organism
Streptococcus agalactiae SA20-06
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.UniRule annotationSAAS annotation

Catalytic activityi

Phosphate + oxaloacetate = H2O + phosphoenolpyruvate + HCO3-.UniRule annotationSAAS annotation

Cofactori

Mg2+UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei138 – 1381UniRule annotation
Active sitei594 – 5941UniRule annotation

GO - Molecular functioni

  1. magnesium ion binding Source: UniProtKB-HAMAP
  2. phosphoenolpyruvate carboxylase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. carbon fixation Source: UniProtKB-HAMAP
  2. oxaloacetate metabolic process Source: UniProtKB-HAMAP
  3. tricarboxylic acid cycle Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

LyaseUniRule annotationSAAS annotation

Keywords - Biological processi

Carbon dioxide fixationUniRule annotationSAAS annotation

Keywords - Ligandi

MagnesiumUniRule annotationSAAS annotation, PyruvateImported

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoenolpyruvate carboxylaseUniRule annotationSAAS annotation (EC:4.1.1.31UniRule annotationSAAS annotation)
Short name:
PEPCUniRule annotation
Short name:
PEPCaseUniRule annotation
Gene namesi
Name:ppcUniRule annotationImported
ORF Names:SaSA20_0635Imported
OrganismiStreptococcus agalactiae SA20-06Imported
Taxonomic identifieri1231389 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliLactobacillalesStreptococcaceaeStreptococcus
ProteomesiUP000000221: Chromosome

Interactioni

Subunit structurei

Homotetramer.UniRule annotation

Family & Domainsi

Sequence similaritiesi

Belongs to the PEPCase type 1 family.UniRule annotation

Phylogenomic databases

KOiK01595.

Family and domain databases

HAMAPiMF_00595. PEPcase_type1.
InterProiIPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view]
PfamiPF00311. PEPcase. 1 hit.
[Graphical view]
PRINTSiPR00150. PEPCARBXLASE.
SUPFAMiSSF51621. SSF51621. 2 hits.
PROSITEiPS00781. PEPCASE_1. 1 hit.
PS00393. PEPCASE_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

K4PP61-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MSHPKLESSS NKEIITEEVG LLKQLLDEAT QKLIGSESFD KIEKIVSLSS
60 70 80 90 100
TDDYTGLKET ISALSNEEMV IVSRYFSILP LLINISEDVD LAYEINYKNN
110 120 130 140 150
LNQDYLGKLS TTIDVVAGHE NAKDILEHVN VVPVLTAHPT QVQRKTVLEL
160 170 180 190 200
TSKIHDLLRK YRDVKAGIVN QEKWYADLRR YIGIIMQTDT IREKKLKVKN
210 220 230 240 250
EITNVMEYYN RSLIKAVTKL TAEYKALAAK KGIHLENPKP LTMGMWIGGD
260 270 280 290 300
RDGNPFVTAE TLRLSAMVQS EVIINHYIEQ LNELYRNMSL SRTRTELSPE
310 320 330 340 350
LVTLANQSQD NSVYRENEPY RKAFNFIQDK LVQTLLNLKV GSYPKEKFVS
360 370 380 390 400
RQESSDIVGR YIKSHIAQVA SDIQTEELPA YATAEEFKQD LLLVKQSLVQ
410 420 430 440 450
HGQDSLVDGE LACLIQAVDI FGFYLATIDM RQDSSINEAC VAELLKSANI
460 470 480 490 500
VDDYSSLSEE EKCQLLLKEL TEDPRTLSST HAPKSELLQK ELAIFQTARE
510 520 530 540 550
LKDQLGEDII KQHIISHTES VSDMFELAIM LKEVGLIDAN QARIQIVPLF
560 570 580 590 600
ETIEDLDNSR DIMTQYLHYE LVKKWVATNN NYQEIMLGYS DSNKDGGYLS
610 620 630 640 650
SGWTLYKAQN ELTKIGEENG IKITFFHGRG GTVGRGGGPS YEAITSQPFG
660 670 680 690 700
SIKDRIRLTE QGEIIENKYG NQDAAYYNLE MLISASIDRM VTRMITNPNE
710 720 730 740 750
IDNFRETMDG IVAESNAVYR NLVFDNPYFY DYFFEASPIK EVSSLNIGSR
760 770 780 790 800
PAARKTITEI SGLRAIPWVF SWSQNRIMFP GWYGVGSAFK HFIEQDEANL
810 820 830 840 850
AKLQTMYQKW PFFNSLLSNV DMVLSKSNMN IALQYAQLAG SKEVRDVFNI
860 870 880 890 900
ILNEWQLTKD MILAIEQHDN LLEENPMLHA SLDYRLPYFN VLNYVQIELI
910 920 930
KRLRSNQLDE DYEKLIHITI NGIATGLRNS G
Length:931
Mass (Da):106,058
Last modified:January 9, 2013 - v1
Checksum:i3C317AC68972D795
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP003919 Genomic DNA. Translation: AFV72103.1.
RefSeqiWP_015058482.1. NC_019048.1.
YP_006951047.1. NC_019048.1.

Genome annotation databases

EnsemblBacteriaiAFV72103; AFV72103; SaSA20_0635.
GeneIDi13907892.
KEGGisags:SaSA20_0635.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP003919 Genomic DNA. Translation: AFV72103.1.
RefSeqiWP_015058482.1. NC_019048.1.
YP_006951047.1. NC_019048.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAFV72103; AFV72103; SaSA20_0635.
GeneIDi13907892.
KEGGisags:SaSA20_0635.

Phylogenomic databases

KOiK01595.

Family and domain databases

HAMAPiMF_00595. PEPcase_type1.
InterProiIPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view]
PfamiPF00311. PEPcase. 1 hit.
[Graphical view]
PRINTSiPR00150. PEPCARBXLASE.
SUPFAMiSSF51621. SSF51621. 2 hits.
PROSITEiPS00781. PEPCASE_1. 1 hit.
PS00393. PEPCASE_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: SA20-06Imported.
  2. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: SA20-06Imported.

Entry informationi

Entry nameiK4PP61_STRAG
AccessioniPrimary (citable) accession number: K4PP61
Entry historyi
Integrated into UniProtKB/TrEMBL: January 9, 2013
Last sequence update: January 9, 2013
Last modified: February 4, 2015
This is version 18 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.