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K4N264

- K4N264_STRPY

UniProt

K4N264 - K4N264_STRPY

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Protein
Phosphoenolpyruvate carboxylase
Gene
ppc, A20_0547
Organism
Streptococcus pyogenes A20
Status
Unreviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle By similarity.UniRule annotationSAAS annotations

Catalytic activityi

Phosphate + oxaloacetate = H2O + phosphoenolpyruvate + HCO3-.UniRule annotationSAAS annotations

Cofactori

Magnesium By similarity.UniRule annotationSAAS annotations

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei138 – 1381 By similarityUniRule annotation
Active sitei583 – 5831 By similarityUniRule annotation

GO - Molecular functioni

  1. magnesium ion binding Source: UniProtKB-HAMAP
  2. phosphoenolpyruvate carboxylase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. carbon fixation Source: UniProtKB-HAMAP
  2. oxaloacetate metabolic process Source: UniProtKB-HAMAP
  3. tricarboxylic acid cycle Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

LyaseUniRule annotationSAAS annotationsImported

Keywords - Biological processi

Carbon dioxide fixationUniRule annotationSAAS annotations

Keywords - Ligandi

MagnesiumUniRule annotationSAAS annotations, PyruvateImported

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoenolpyruvate carboxylaseUniRule annotation (EC:4.1.1.31UniRule annotation)
Short name:
PEPCUniRule annotation
Short name:
PEPCaseUniRule annotation
Gene namesi
Name:ppcUniRule annotationImported
ORF Names:A20_0547Imported
OrganismiStreptococcus pyogenes A20Imported
Taxonomic identifieri1235829 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliLactobacillalesStreptococcaceaeStreptococcus
ProteomesiUP000001267: Chromosome

Interactioni

Subunit structurei

Homotetramer By similarity.UniRule annotation

Family & Domainsi

Sequence similaritiesi

Belongs to the PEPCase type 1 family.UniRule annotation

Phylogenomic databases

KOiK01595.

Family and domain databases

HAMAPiMF_00595. PEPcase_type1.
InterProiIPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view]
PfamiPF00311. PEPcase. 1 hit.
[Graphical view]
PRINTSiPR00150. PEPCARBXLASE.
SUPFAMiSSF51621. SSF51621. 1 hit.
PROSITEiPS00781. PEPCASE_1. 1 hit.
PS00393. PEPCASE_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

K4N264-1 [UniParc]FASTAAdd to Basket

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MPLKKLESSN NQDIIAEEVA LLKEMLENIT RRMIGDDAFT VIESIMVLSE    50
KQDYIELEKV VANISNQEME VISRYFSILP LLINISEDVD LAYEINYQNN 100
TDTDYLGKLA LTIKDLAGKD NGKDILEQVN VVPVLTAHPT QVQRKTILEL 150
TTHIHKLLRK YRDAKAGVIN LEKWRQELYR YIEMIMQTDI IREKKLQVKN 200
EIKNVMQYYD GSLIQAVTKL TTEYKNLAQK HGLELDNPKP ITMGMWIGGD 250
RDGNPFVTAE TLCLSATVQS EVILNYYIDE LAALYRTFSL SSTLVQPNSE 300
VERLASLSQD QSIYRGNEPY RRAFHYIQSR LKQTQIQLTN QPAARMSSSV 350
GLNTSAWSSP ASLENPILAY DSPVDFKADL KAIEQSLLDN GNSALIEGDL 400
REVMQAVDIF GFFLASIDMR QDSSVQEACV AELLKGANIV DDYSSLSETE 450
KCDVLLQQLM EEPRTLSSAA VAKSDLLEKE LAIYTTAREL KDKLGEEVIK 500
QHIISHTESV SDMFELAIML KEVGLVDQQR ARVQIVPLFE TIEDLDNARD 550
IMAAYLSHDI VKSWIATNRN YQEIMLGYSD SNKDGGYLAS GWTLYKAQNE 600
LTAIGEEHGV KITFFHGRGG TVGRGGGPSY DAITSQPFGS IKDRIRLTEQ 650
GEIIENKYGN KDVAYYHLEM LISASINRMV TQMITDPNEI DSFREIMDSI 700
VADSNIIYRK LVFDNPHFYD YFFEASPIKE VSSLNIGSRP AARKTITEIT 750
GLRAIPWVFS WSQNRIMFPG WYGVGSAFKR YIDRAQGNLE RLQHMYQTWP 800
FFHSLLSNVD MVLSKSNMNI AFQYAQLAER QDVRDVFYEI LDEWQLTKNV 850
ILAIQDHDAL LEDNPSLKHS LKSRLPYFNV LNYIQIELIK RWRNNQLDEN 900
DEKLIHTTIN GIATGLRNSG 920
Length:920
Mass (Da):104,777
Last modified:January 9, 2013 - v1
Checksum:i0F7C6F5D4C1C9737
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP003901 Genomic DNA. Translation: AFV37633.1.
RefSeqiYP_006932586.1. NC_018936.1.

Genome annotation databases

EnsemblBacteriaiAFV37633; AFV37633; A20_0547.
GeneIDi13864182.
KEGGispya:A20_0547.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP003901 Genomic DNA. Translation: AFV37633.1 .
RefSeqi YP_006932586.1. NC_018936.1.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AFV37633 ; AFV37633 ; A20_0547 .
GeneIDi 13864182.
KEGGi spya:A20_0547.

Phylogenomic databases

KOi K01595.

Family and domain databases

HAMAPi MF_00595. PEPcase_type1.
InterProi IPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view ]
Pfami PF00311. PEPcase. 1 hit.
[Graphical view ]
PRINTSi PR00150. PEPCARBXLASE.
SUPFAMi SSF51621. SSF51621. 1 hit.
PROSITEi PS00781. PEPCASE_1. 1 hit.
PS00393. PEPCASE_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Complete genome of Streptococcus pyogenes A20. A clinical isolate was cultured from a necrotizing fasciitis patient in Tainan Provincial Hospital, Taiwan."
    Zheng P.X., Chung K.T., Sun H.S., Wu J.J.
    Submitted (OCT-2012) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: A20Imported.

Entry informationi

Entry nameiK4N264_STRPY
AccessioniPrimary (citable) accession number: K4N264
Entry historyi
Integrated into UniProtKB/TrEMBL: January 9, 2013
Last sequence update: January 9, 2013
Last modified: June 11, 2014
This is version 11 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome

External Data

Dasty 3

Similar proteinsi