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K4IE64

- K4IE64_PSYTT

UniProt

K4IE64 - K4IE64_PSYTT

Protein

Thymidine kinase

Gene

tdk

Organism
Psychroflexus torquis (strain ATCC 700755 / ACAM 623)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 14 (01 Oct 2014)
      Sequence version 1 (09 Jan 2013)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    ATP + thymidine = ADP + thymidine 5'-phosphate.UniRule annotationSAAS annotation

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei94 – 941Proton acceptorUniRule annotation

    Regions

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Nucleotide bindingi21 – 288ATPUniRule annotation
    Nucleotide bindingi93 – 964ATPUniRule annotation

    GO - Molecular functioni

    1. ATP binding Source: UniProtKB-HAMAP
    2. thymidine kinase activity Source: UniProtKB-HAMAP

    GO - Biological processi

    1. DNA replication Source: UniProtKB-KW

    Keywords - Molecular functioni

    KinaseUniRule annotationSAAS annotationImported, Transferase

    Keywords - Biological processi

    DNA synthesisUniRule annotationSAAS annotation

    Keywords - Ligandi

    ATP-bindingUniRule annotationSAAS annotation, Nucleotide-binding

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Thymidine kinaseUniRule annotation (EC:2.7.1.21UniRule annotation)
    Gene namesi
    Name:tdkUniRule annotation
    Ordered Locus Names:P700755_002069Imported
    OrganismiPsychroflexus torquis (strain ATCC 700755 / ACAM 623)Imported
    Taxonomic identifieri313595 [NCBI]
    Taxonomic lineageiBacteriaBacteroidetesFlavobacteriiaFlavobacterialesFlavobacteriaceaePsychroflexus
    ProteomesiUP000008514: Chromosome

    Subcellular locationi

    Cytoplasm UniRule annotation

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    CytoplasmUniRule annotation

    Interactioni

    Subunit structurei

    Homotetramer.UniRule annotation

    Structurei

    3D structure databases

    ProteinModelPortaliK4IE64.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the thymidine kinase family.UniRule annotation

    Phylogenomic databases

    KOiK00857.

    Family and domain databases

    HAMAPiMF_00124. Thymidine_kinase.
    InterProiIPR027417. P-loop_NTPase.
    IPR001267. Thymidine_kinase.
    IPR020634. Thymidine_kinase_subgr.
    [Graphical view]
    PANTHERiPTHR11441. PTHR11441. 1 hit.
    PfamiPF00265. TK. 1 hit.
    [Graphical view]
    PIRSFiPIRSF035805. TK_cell. 1 hit.
    SUPFAMiSSF52540. SSF52540. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    K4IE64-1 [UniParc]FASTAAdd to Basket

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    MFLENTVNHK EQFGWIEVIC GSMFSGKTEE LIRRLKRAKF AKQKVEIFKP    50
    QIDRRYDDTD VVSHDENSIR STPVPAAANI RLLADGCEVV GIDEAQFFDD 100
    EIISVCNDLA NRGVRVIVAG LDMDFKGNPF GPMPNLMATA EYVTKVHAVC 150
    TRTGNLAQYS FRKSSKEDLV LLGETDEYEP LSRAAYFKAM LKEKVKRIEV 200
    KDSEELSSKK PE 212
    Length:212
    Mass (Da):23,987
    Last modified:January 9, 2013 - v1
    Checksum:i234D131C2699FF6F
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP003879 Genomic DNA. Translation: AFU68862.1.
    RefSeqiWP_015024444.1. NC_018721.1.
    YP_006867612.1. NC_018721.1.

    Genome annotation databases

    EnsemblBacteriaiAFU68862; AFU68862; P700755_002069.
    GeneIDi13805163.
    KEGGiptq:P700755_002069.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP003879 Genomic DNA. Translation: AFU68862.1 .
    RefSeqi WP_015024444.1. NC_018721.1.
    YP_006867612.1. NC_018721.1.

    3D structure databases

    ProteinModelPortali K4IE64.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AFU68862 ; AFU68862 ; P700755_002069 .
    GeneIDi 13805163.
    KEGGi ptq:P700755_002069.

    Phylogenomic databases

    KOi K00857.

    Family and domain databases

    HAMAPi MF_00124. Thymidine_kinase.
    InterProi IPR027417. P-loop_NTPase.
    IPR001267. Thymidine_kinase.
    IPR020634. Thymidine_kinase_subgr.
    [Graphical view ]
    PANTHERi PTHR11441. PTHR11441. 1 hit.
    Pfami PF00265. TK. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF035805. TK_cell. 1 hit.
    SUPFAMi SSF52540. SSF52540. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. Bowman J., Ferriera S., Johnson J., Kravitz S., Halpern A., Remington K., Beeson K., Tran B., Rogers Y.-H., Friedman R., Venter J.C.
      Submitted (MAR-2006) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    2. "The complete sequence of Psychroflexus torquis an extreme psychrophile from sea-ice that is stimulated by light."
      Feng S., Powell S.M., Bowman J.P.
      Submitted (SEP-2012) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 700755 / ACAM 623Imported.

    Entry informationi

    Entry nameiK4IE64_PSYTT
    AccessioniPrimary (citable) accession number: K4IE64
    Entry historyi
    Integrated into UniProtKB/TrEMBL: January 9, 2013
    Last sequence update: January 9, 2013
    Last modified: October 1, 2014
    This is version 14 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3