ID   K4HPL6_HUMAN            Unreviewed;        89 AA.
AC   K4HPL6;
DT   09-JAN-2013, integrated into UniProtKB/TrEMBL.
DT   09-JAN-2013, sequence version 1.
DT   22-FEB-2023, entry version 21.
DE   SubName: Full=MHC class II antigen {ECO:0000313|EMBL:AFU52874.1};
DE   Flags: Fragment;
GN   Name=HLA-DRB1 {ECO:0000313|EMBL:AFU52874.1};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|EMBL:AFU52874.1};
RN   [1] {ECO:0000313|EMBL:AFU52874.1}
RP   NUCLEOTIDE SEQUENCE.
RX   PubMed=23330724; DOI=10.1111/tan.12050;
RA   Hommel-Berrey G.A., House K.D., Backfish K.A., Arnoff T.S.,
RA   Lobashevsky A.L.;
RT   "Identification of a novel HLA-DRB1 allele, DRB1*09:20, by sequence-based
RT   typing in an unrelated bone marrow donor.";
RL   Tissue Antigens 81:125-126(2013).
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DR   EMBL; JX310102; AFU52874.1; -; Genomic_DNA.
DR   AlphaFoldDB; K4HPL6; -.
DR   PeptideAtlas; K4HPL6; -.
DR   ChiTaRS; HLA-DRB1; human.
DR   GO; GO:0042613; C:MHC class II protein complex; IEA:InterPro.
DR   GO; GO:0019882; P:antigen processing and presentation; IEA:InterPro.
DR   GO; GO:0006955; P:immune response; IEA:InterPro.
DR   InterPro; IPR011162; MHC_I/II-like_Ag-recog.
DR   InterPro; IPR014745; MHC_II_a/b_N.
DR   InterPro; IPR000353; MHC_II_b_N.
DR   PANTHER; PTHR19944:SF97; HLA CLASS II HISTOCOMPATIBILITY ANTIGEN, DR BETA 5 CHAIN; 1.
DR   PANTHER; PTHR19944; MHC CLASS II-RELATED; 1.
DR   Pfam; PF00969; MHC_II_beta; 1.
DR   SMART; SM00921; MHC_II_beta; 1.
DR   SUPFAM; SSF54452; MHC antigen-recognition domain; 1.
PE   4: Predicted;
KW   Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW   Signal {ECO:0000256|ARBA:ARBA00022729}.
FT   DOMAIN          8..82
FT                   /note="MHC class II beta chain N-terminal"
FT                   /evidence="ECO:0000259|SMART:SM00921"
FT   NON_TER         1
FT                   /evidence="ECO:0000313|EMBL:AFU52874.1"
FT   NON_TER         89
FT                   /evidence="ECO:0000313|EMBL:AFU52874.1"
SQ   SEQUENCE   89 AA;  10733 MW;  895F690B69853D97 CRC64;
     RFLQQDKFEC HFFNGTERVR YLHRGIYNQE ENVRFDSDVG EYRAVTELGR PVAESWNSQK
     DFLERRRAEV DTVCRHNYGV GESFTVQRR
//