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K4HD46

- K4HD46_KLEPN

UniProt

K4HD46 - K4HD46_KLEPN

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Protein

Phosphoenolpyruvate carboxylase

Gene
ppc, A79E_4943
Organism
Klebsiella pneumoniae subsp. pneumoniae 1084
Status
Unreviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle By similarity.UniRule annotationSAAS annotations

Catalytic activityi

Phosphate + oxaloacetate = H2O + phosphoenolpyruvate + HCO3-.UniRule annotationSAAS annotations

Cofactori

Magnesium By similarity.UniRule annotationSAAS annotations

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei138 – 1381 By similarityUniRule annotation
Active sitei546 – 5461 By similarityUniRule annotation

GO - Molecular functioni

  1. magnesium ion binding Source: UniProtKB-HAMAP
  2. phosphoenolpyruvate carboxylase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. carbon fixation Source: UniProtKB-HAMAP
  2. oxaloacetate metabolic process Source: UniProtKB-HAMAP
  3. tricarboxylic acid cycle Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

LyaseUniRule annotationSAAS annotations

Keywords - Biological processi

Carbon dioxide fixationUniRule annotationSAAS annotations

Keywords - Ligandi

MagnesiumUniRule annotationSAAS annotations, PyruvateImported

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoenolpyruvate carboxylaseUniRule annotation (EC:4.1.1.31UniRule annotation)
Short name:
PEPCUniRule annotation
Short name:
PEPCaseUniRule annotation
Gene namesi
Name:ppcUniRule annotation
ORF Names:A79E_4943Imported
OrganismiKlebsiella pneumoniae subsp. pneumoniae 1084Imported
Taxonomic identifieri1193292 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeKlebsiella
ProteomesiUP000009209: Chromosome

Interactioni

Subunit structurei

Homotetramer By similarity.UniRule annotation

Family & Domainsi

Sequence similaritiesi

Belongs to the PEPCase type 1 family.UniRule annotation

Phylogenomic databases

KOiK01595.

Family and domain databases

HAMAPiMF_00595. PEPcase_type1.
InterProiIPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view]
PfamiPF00311. PEPcase. 1 hit.
[Graphical view]
PRINTSiPR00150. PEPCARBXLASE.
SUPFAMiSSF51621. SSF51621. 1 hit.
PROSITEiPS00781. PEPCASE_1. 1 hit.
PS00393. PEPCASE_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

K4HD46-1 [UniParc]FASTAAdd to Basket

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MNEQYSALRS NVSMLGKVLG DTIKDALGEN ILDRVETIRK LSKSSRAGNE    50
ANRQELLTTL QNLSNDELLP VARAFSQFLN LANTAEQYHS ISANGEAASN 100
PEVIARTLRK LKDQPNLNEE TIKQAVESLS LELVLTAHPT EITRRTLIHK 150
MVEVNNCLKQ LDNKDIADYE HHQLMRRLRQ LIAQSWHTDE IRKHRPSPVD 200
EAKWGFAVVE NSLWEGVPNY LRELNEQLEA NLGYQLPVDF VPVRFTSWMG 250
GDRDGNPNVT ADITRHVLLL SRWKATDLFL KDVQVLISEL SMVECTDELR 300
ALAGAEGAQE PYRYLMKKLR SQLMETQAWL EARLKGQKLP KPAGLITQNE 350
QLWEPLYACY KSLQACGMGI IANGELLDTL RRVKSFGVPL VRIDIRQEST 400
RHTEALGEMT RYLGIGDYES WSEADKQAFL IRELNSKRPL LPRQWEPSEE 450
TREVLDTCKV IAEAPRGSIA AYVISMAKTP SDVLAVHLLL KEAGIGFALP 500
VAPLFETLDD LNNANDVMTQ LLNIDWYRGF IQGKQMVMIG YSDSAKDAGV 550
MAASWAQYQA QDALIKTCEK AGIELTLFHG RGGSIGRGGA PAHAALLSQP 600
PGSLKGGLRV TEQGEMIRFK YGLPEVTISS LSLYTSAILE ANLLPPPEPK 650
AEWRDIMAEL SDVSCKMYRG YVRENKDFVP YFRSATPEQE LGKLPLGSRP 700
AKRRPTGGVE SLRAIPWIFA WTQNRLMLPA WLGAGAALQK VVEGGKQSEL 750
EAMCRDWPFF STRLGMLEMV YSKADLWLAE YYDQRLVKPE LWALGSELRK 800
LLAADINVVL AIANDSHLMA DLPWIAESIQ LRNIYTDPLN VLQAELLHRS 850
RQAEEEGKDP DPRVEQALMV TIAGVAAGMR NTG 883
Length:883
Mass (Da):98,946
Last modified:January 9, 2013 - v1
Checksum:i7E3810AF3B98025F
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP003785 Genomic DNA. Translation: AFQ68115.1.
RefSeqiYP_006638675.1. NC_018522.1.

Genome annotation databases

EnsemblBacteriaiAFQ68115; AFQ68115; A79E_4943.
GeneIDi13526680.
KEGGikpp:A79E_4943.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP003785 Genomic DNA. Translation: AFQ68115.1 .
RefSeqi YP_006638675.1. NC_018522.1.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AFQ68115 ; AFQ68115 ; A79E_4943 .
GeneIDi 13526680.
KEGGi kpp:A79E_4943.

Phylogenomic databases

KOi K01595.

Family and domain databases

HAMAPi MF_00595. PEPcase_type1.
InterProi IPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view ]
Pfami PF00311. PEPcase. 1 hit.
[Graphical view ]
PRINTSi PR00150. PEPCARBXLASE.
SUPFAMi SSF51621. SSF51621. 1 hit.
PROSITEi PS00781. PEPCASE_1. 1 hit.
PS00393. PEPCASE_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Complete Genome Sequence of Klebsiella pneumoniae 1084, a Hypermucoviscosity-Negative K1 Clinical Strain."
    Lin A.C., Liao T.L., Lin Y.C., Lai Y.C., Lu M.C., Chen Y.T.
    J. Bacteriol. 194:6316-6316(2012) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 1084Imported.

Entry informationi

Entry nameiK4HD46_KLEPN
AccessioniPrimary (citable) accession number: K4HD46
Entry historyi
Integrated into UniProtKB/TrEMBL: January 9, 2013
Last sequence update: January 9, 2013
Last modified: June 11, 2014
This is version 11 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome

External Data

Dasty 3

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