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K4H908

- K4H908_KLEPN

UniProt

K4H908 - K4H908_KLEPN

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Protein

Xylose isomerase

Gene
xylA, A79E_4434
Organism
Klebsiella pneumoniae subsp. pneumoniae 1084
Status
Unreviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

D-xylopyranose = D-xylulose.UniRule annotationSAAS annotations

Cofactori

Binds 2 magnesium ions per subunit By similarity.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei101 – 1011 By similarityUniRule annotation
Active sitei104 – 1041 By similarityUniRule annotation
Metal bindingi232 – 2321Magnesium 1 By similarityUniRule annotation
Metal bindingi268 – 2681Magnesium 1 By similarityUniRule annotation
Metal bindingi268 – 2681Magnesium 2 By similarityUniRule annotation
Metal bindingi271 – 2711Magnesium 2 By similarityUniRule annotation
Metal bindingi296 – 2961Magnesium 1 By similarityUniRule annotation
Metal bindingi307 – 3071Magnesium 2 By similarityUniRule annotation
Metal bindingi309 – 3091Magnesium 2 By similarityUniRule annotation
Metal bindingi339 – 3391Magnesium 1 By similarityUniRule annotation

GO - Molecular functioni

  1. magnesium ion binding Source: UniProtKB-HAMAP
  2. xylose isomerase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. D-xylose metabolic process Source: UniProtKB-HAMAP
  2. pentose-phosphate shunt Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

IsomeraseUniRule annotationSAAS annotationsImported

Keywords - Biological processi

Carbohydrate metabolism, Pentose shuntUniRule annotationSAAS annotations, Xylose metabolismUniRule annotationSAAS annotations

Keywords - Ligandi

MagnesiumUniRule annotationSAAS annotations, Metal-bindingUniRule annotationSAAS annotations

Names & Taxonomyi

Protein namesi
Recommended name:
Xylose isomeraseUniRule annotation (EC:5.3.1.5UniRule annotation)
Gene namesi
Name:xylAUniRule annotation
ORF Names:A79E_4434Imported
OrganismiKlebsiella pneumoniae subsp. pneumoniae 1084Imported
Taxonomic identifieri1193292 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeKlebsiella
ProteomesiUP000009209: Chromosome

Subcellular locationi

Cytoplasm By similarity UniRule annotationSAAS annotations

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

CytoplasmUniRule annotationSAAS annotations

Interactioni

Subunit structurei

Homotetramer By similarity.UniRule annotationSAAS annotations

Structurei

3D structure databases

ProteinModelPortaliK4H908.

Family & Domainsi

Sequence similaritiesi

Belongs to the xylose isomerase family.UniRule annotation

Phylogenomic databases

KOiK01805.

Family and domain databases

Gene3Di3.20.20.150. 1 hit.
HAMAPiMF_00455. Xylose_isom_A.
InterProiIPR013022. Xyl_isomerase-like_TIM-brl.
IPR013452. Xylose_isom_bac.
IPR001998. Xylose_isomerase.
[Graphical view]
PfamiPF01261. AP_endonuc_2. 1 hit.
[Graphical view]
PRINTSiPR00688. XYLOSISMRASE.
SUPFAMiSSF51658. SSF51658. 1 hit.
TIGRFAMsiTIGR02630. xylose_isom_A. 1 hit.
PROSITEiPS51415. XYLOSE_ISOMERASE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

K4H908-1 [UniParc]FASTAAdd to Basket

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MQTYFDQVDR VRFAGPITDN PLAFRHYNPD EIVLGKRMAD HLRFAACYWH    50
NFCWNGADMF GAGSFERPWQ AAGDALEMAK RKADVAFEFF YKLNVPYYCF 100
HDVDVSPEGA SLKEYLHNFA VMTEVLAEKQ QQTGVKLLWG TANCFTHPRY 150
GAGAATNPDP EVFAWAATQV VTAMNATHQL GGENYVLWGG REGYESLLNT 200
DLRQEREQIG RFLQMVVEHK HKIGFGGTLL IEPKPQEPTK HQYDYDVATV 250
YGFLKQFGLE NEIKVNIEAN HATLAGHSFH HEIASAIALG IFGSVDANRG 300
DAQLGWDTDQ FPNSIEENTL VMYEILKAGG FTTGGLNFDA KVRRQSTDKY 350
DMFYGHIGAM DVMALSLKLA ARMIEDGKLD QGLAKRYAGW QGELGQKIMS 400
GQMSLDNIAR YAEQHNLNPQ PQSGRQELLE NLVNTYIFG 439
Length:439
Mass (Da):49,380
Last modified:January 9, 2013 - v1
Checksum:iA0E929F444C8B7DD
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP003785 Genomic DNA. Translation: AFQ67647.1.
RefSeqiYP_006638195.1. NC_018522.1.

Genome annotation databases

EnsemblBacteriaiAFQ67647; AFQ67647; A79E_4434.
GeneIDi13526172.
KEGGikpp:A79E_4434.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP003785 Genomic DNA. Translation: AFQ67647.1 .
RefSeqi YP_006638195.1. NC_018522.1.

3D structure databases

ProteinModelPortali K4H908.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AFQ67647 ; AFQ67647 ; A79E_4434 .
GeneIDi 13526172.
KEGGi kpp:A79E_4434.

Phylogenomic databases

KOi K01805.

Family and domain databases

Gene3Di 3.20.20.150. 1 hit.
HAMAPi MF_00455. Xylose_isom_A.
InterProi IPR013022. Xyl_isomerase-like_TIM-brl.
IPR013452. Xylose_isom_bac.
IPR001998. Xylose_isomerase.
[Graphical view ]
Pfami PF01261. AP_endonuc_2. 1 hit.
[Graphical view ]
PRINTSi PR00688. XYLOSISMRASE.
SUPFAMi SSF51658. SSF51658. 1 hit.
TIGRFAMsi TIGR02630. xylose_isom_A. 1 hit.
PROSITEi PS51415. XYLOSE_ISOMERASE. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Complete Genome Sequence of Klebsiella pneumoniae 1084, a Hypermucoviscosity-Negative K1 Clinical Strain."
    Lin A.C., Liao T.L., Lin Y.C., Lai Y.C., Lu M.C., Chen Y.T.
    J. Bacteriol. 194:6316-6316(2012) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 1084Imported.

Entry informationi

Entry nameiK4H908_KLEPN
AccessioniPrimary (citable) accession number: K4H908
Entry historyi
Integrated into UniProtKB/TrEMBL: January 9, 2013
Last sequence update: January 9, 2013
Last modified: June 11, 2014
This is version 12 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome

External Data

Dasty 3

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