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K4H908

- K4H908_KLEPN

UniProt

K4H908 - K4H908_KLEPN

Protein

Xylose isomerase

Gene

xylA

Organism
Klebsiella pneumoniae subsp. pneumoniae 1084
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 13 (01 Oct 2014)
      Sequence version 1 (09 Jan 2013)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    D-xylopyranose = D-xylulose.UniRule annotationSAAS annotation

    Cofactori

    Binds 2 magnesium ions per subunit.UniRule annotation

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei101 – 1011UniRule annotation
    Active sitei104 – 1041UniRule annotation
    Metal bindingi232 – 2321Magnesium 1UniRule annotation
    Metal bindingi268 – 2681Magnesium 1UniRule annotation
    Metal bindingi268 – 2681Magnesium 2UniRule annotation
    Metal bindingi271 – 2711Magnesium 2UniRule annotation
    Metal bindingi296 – 2961Magnesium 1UniRule annotation
    Metal bindingi307 – 3071Magnesium 2UniRule annotation
    Metal bindingi309 – 3091Magnesium 2UniRule annotation
    Metal bindingi339 – 3391Magnesium 1UniRule annotation

    GO - Molecular functioni

    1. magnesium ion binding Source: UniProtKB-HAMAP
    2. xylose isomerase activity Source: UniProtKB-HAMAP

    GO - Biological processi

    1. D-xylose metabolic process Source: UniProtKB-HAMAP
    2. pentose-phosphate shunt Source: UniProtKB-HAMAP

    Keywords - Molecular functioni

    IsomeraseUniRule annotationSAAS annotationImported

    Keywords - Biological processi

    Carbohydrate metabolism, Pentose shuntUniRule annotationSAAS annotation, Xylose metabolismUniRule annotationSAAS annotation

    Keywords - Ligandi

    MagnesiumUniRule annotationSAAS annotation, Metal-bindingUniRule annotationSAAS annotation

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Xylose isomeraseUniRule annotation (EC:5.3.1.5UniRule annotation)
    Gene namesi
    Name:xylAUniRule annotation
    ORF Names:A79E_4434Imported
    OrganismiKlebsiella pneumoniae subsp. pneumoniae 1084Imported
    Taxonomic identifieri1193292 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeKlebsiella
    ProteomesiUP000009209: Chromosome

    Subcellular locationi

    Cytoplasm UniRule annotationSAAS annotation

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    CytoplasmUniRule annotationSAAS annotation

    Interactioni

    Subunit structurei

    Homotetramer.UniRule annotationSAAS annotation

    Structurei

    3D structure databases

    ProteinModelPortaliK4H908.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the xylose isomerase family.UniRule annotation

    Phylogenomic databases

    KOiK01805.

    Family and domain databases

    Gene3Di3.20.20.150. 1 hit.
    HAMAPiMF_00455. Xylose_isom_A.
    InterProiIPR013022. Xyl_isomerase-like_TIM-brl.
    IPR013452. Xylose_isom_bac.
    IPR001998. Xylose_isomerase.
    [Graphical view]
    PfamiPF01261. AP_endonuc_2. 1 hit.
    [Graphical view]
    PRINTSiPR00688. XYLOSISMRASE.
    SUPFAMiSSF51658. SSF51658. 1 hit.
    TIGRFAMsiTIGR02630. xylose_isom_A. 1 hit.
    PROSITEiPS51415. XYLOSE_ISOMERASE. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    K4H908-1 [UniParc]FASTAAdd to Basket

    « Hide

    MQTYFDQVDR VRFAGPITDN PLAFRHYNPD EIVLGKRMAD HLRFAACYWH    50
    NFCWNGADMF GAGSFERPWQ AAGDALEMAK RKADVAFEFF YKLNVPYYCF 100
    HDVDVSPEGA SLKEYLHNFA VMTEVLAEKQ QQTGVKLLWG TANCFTHPRY 150
    GAGAATNPDP EVFAWAATQV VTAMNATHQL GGENYVLWGG REGYESLLNT 200
    DLRQEREQIG RFLQMVVEHK HKIGFGGTLL IEPKPQEPTK HQYDYDVATV 250
    YGFLKQFGLE NEIKVNIEAN HATLAGHSFH HEIASAIALG IFGSVDANRG 300
    DAQLGWDTDQ FPNSIEENTL VMYEILKAGG FTTGGLNFDA KVRRQSTDKY 350
    DMFYGHIGAM DVMALSLKLA ARMIEDGKLD QGLAKRYAGW QGELGQKIMS 400
    GQMSLDNIAR YAEQHNLNPQ PQSGRQELLE NLVNTYIFG 439
    Length:439
    Mass (Da):49,380
    Last modified:January 9, 2013 - v1
    Checksum:iA0E929F444C8B7DD
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP003785 Genomic DNA. Translation: AFQ67647.1.
    RefSeqiYP_006638195.1. NC_018522.1.

    Genome annotation databases

    EnsemblBacteriaiAFQ67647; AFQ67647; A79E_4434.
    GeneIDi13526172.
    KEGGikpp:A79E_4434.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP003785 Genomic DNA. Translation: AFQ67647.1 .
    RefSeqi YP_006638195.1. NC_018522.1.

    3D structure databases

    ProteinModelPortali K4H908.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AFQ67647 ; AFQ67647 ; A79E_4434 .
    GeneIDi 13526172.
    KEGGi kpp:A79E_4434.

    Phylogenomic databases

    KOi K01805.

    Family and domain databases

    Gene3Di 3.20.20.150. 1 hit.
    HAMAPi MF_00455. Xylose_isom_A.
    InterProi IPR013022. Xyl_isomerase-like_TIM-brl.
    IPR013452. Xylose_isom_bac.
    IPR001998. Xylose_isomerase.
    [Graphical view ]
    Pfami PF01261. AP_endonuc_2. 1 hit.
    [Graphical view ]
    PRINTSi PR00688. XYLOSISMRASE.
    SUPFAMi SSF51658. SSF51658. 1 hit.
    TIGRFAMsi TIGR02630. xylose_isom_A. 1 hit.
    PROSITEi PS51415. XYLOSE_ISOMERASE. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Complete Genome Sequence of Klebsiella pneumoniae 1084, a Hypermucoviscosity-Negative K1 Clinical Strain."
      Lin A.C., Liao T.L., Lin Y.C., Lai Y.C., Lu M.C., Chen Y.T.
      J. Bacteriol. 194:6316-6316(2012) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: 1084Imported.

    Entry informationi

    Entry nameiK4H908_KLEPN
    AccessioniPrimary (citable) accession number: K4H908
    Entry historyi
    Integrated into UniProtKB/TrEMBL: January 9, 2013
    Last sequence update: January 9, 2013
    Last modified: October 1, 2014
    This is version 13 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteomeImported

    External Data

    Dasty 3