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K4H908

- K4H908_KLEPN

UniProt

K4H908 - K4H908_KLEPN

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Protein

Xylose isomerase

Gene

xylA

Organism
Klebsiella pneumoniae subsp. pneumoniae 1084
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalytic activityi

D-xylopyranose = D-xylulose.UniRule annotationSAAS annotation

Cofactori

Binds 2 magnesium ions per subunit.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei101 – 1011UniRule annotation
Active sitei104 – 1041UniRule annotation
Metal bindingi232 – 2321Magnesium 1UniRule annotation
Metal bindingi268 – 2681Magnesium 1UniRule annotation
Metal bindingi268 – 2681Magnesium 2UniRule annotation
Metal bindingi271 – 2711Magnesium 2UniRule annotation
Metal bindingi296 – 2961Magnesium 1UniRule annotation
Metal bindingi307 – 3071Magnesium 2UniRule annotation
Metal bindingi309 – 3091Magnesium 2UniRule annotation
Metal bindingi339 – 3391Magnesium 1UniRule annotation

GO - Molecular functioni

  1. magnesium ion binding Source: UniProtKB-HAMAP
  2. xylose isomerase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. D-xylose metabolic process Source: UniProtKB-HAMAP
  2. pentose-phosphate shunt Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

IsomeraseUniRule annotation

Keywords - Biological processi

Carbohydrate metabolism, Pentose shuntUniRule annotation, Xylose metabolismUniRule annotation

Keywords - Ligandi

MagnesiumUniRule annotationSAAS annotation, Metal-bindingUniRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Xylose isomeraseUniRule annotation (EC:5.3.1.5UniRule annotation)
Gene namesi
Name:xylAUniRule annotation
ORF Names:A79E_4434Imported
OrganismiKlebsiella pneumoniae subsp. pneumoniae 1084Imported
Taxonomic identifieri1193292 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeKlebsiella
ProteomesiUP000009209: Chromosome

Subcellular locationi

Cytoplasm UniRule annotationSAAS annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

CytoplasmUniRule annotationSAAS annotation

Interactioni

Subunit structurei

Homotetramer.UniRule annotationSAAS annotation

Structurei

3D structure databases

ProteinModelPortaliK4H908.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the xylose isomerase family.UniRule annotation

Phylogenomic databases

KOiK01805.

Family and domain databases

Gene3Di3.20.20.150. 1 hit.
HAMAPiMF_00455. Xylose_isom_A.
InterProiIPR013022. Xyl_isomerase-like_TIM-brl.
IPR013452. Xylose_isom_bac.
IPR001998. Xylose_isomerase.
[Graphical view]
PfamiPF01261. AP_endonuc_2. 1 hit.
[Graphical view]
PRINTSiPR00688. XYLOSISMRASE.
SUPFAMiSSF51658. SSF51658. 1 hit.
TIGRFAMsiTIGR02630. xylose_isom_A. 1 hit.
PROSITEiPS51415. XYLOSE_ISOMERASE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

K4H908-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MQTYFDQVDR VRFAGPITDN PLAFRHYNPD EIVLGKRMAD HLRFAACYWH
60 70 80 90 100
NFCWNGADMF GAGSFERPWQ AAGDALEMAK RKADVAFEFF YKLNVPYYCF
110 120 130 140 150
HDVDVSPEGA SLKEYLHNFA VMTEVLAEKQ QQTGVKLLWG TANCFTHPRY
160 170 180 190 200
GAGAATNPDP EVFAWAATQV VTAMNATHQL GGENYVLWGG REGYESLLNT
210 220 230 240 250
DLRQEREQIG RFLQMVVEHK HKIGFGGTLL IEPKPQEPTK HQYDYDVATV
260 270 280 290 300
YGFLKQFGLE NEIKVNIEAN HATLAGHSFH HEIASAIALG IFGSVDANRG
310 320 330 340 350
DAQLGWDTDQ FPNSIEENTL VMYEILKAGG FTTGGLNFDA KVRRQSTDKY
360 370 380 390 400
DMFYGHIGAM DVMALSLKLA ARMIEDGKLD QGLAKRYAGW QGELGQKIMS
410 420 430
GQMSLDNIAR YAEQHNLNPQ PQSGRQELLE NLVNTYIFG
Length:439
Mass (Da):49,380
Last modified:January 9, 2013 - v1
Checksum:iA0E929F444C8B7DD
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP003785 Genomic DNA. Translation: AFQ67647.1.
RefSeqiWP_012737320.1. NC_018522.1.
YP_006638195.1. NC_018522.1.

Genome annotation databases

EnsemblBacteriaiAFQ67647; AFQ67647; A79E_4434.
GeneIDi13526172.
KEGGikpp:A79E_4434.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP003785 Genomic DNA. Translation: AFQ67647.1 .
RefSeqi WP_012737320.1. NC_018522.1.
YP_006638195.1. NC_018522.1.

3D structure databases

ProteinModelPortali K4H908.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AFQ67647 ; AFQ67647 ; A79E_4434 .
GeneIDi 13526172.
KEGGi kpp:A79E_4434.

Phylogenomic databases

KOi K01805.

Family and domain databases

Gene3Di 3.20.20.150. 1 hit.
HAMAPi MF_00455. Xylose_isom_A.
InterProi IPR013022. Xyl_isomerase-like_TIM-brl.
IPR013452. Xylose_isom_bac.
IPR001998. Xylose_isomerase.
[Graphical view ]
Pfami PF01261. AP_endonuc_2. 1 hit.
[Graphical view ]
PRINTSi PR00688. XYLOSISMRASE.
SUPFAMi SSF51658. SSF51658. 1 hit.
TIGRFAMsi TIGR02630. xylose_isom_A. 1 hit.
PROSITEi PS51415. XYLOSE_ISOMERASE. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Complete Genome Sequence of Klebsiella pneumoniae 1084, a Hypermucoviscosity-Negative K1 Clinical Strain."
    Lin A.C., Liao T.L., Lin Y.C., Lai Y.C., Lu M.C., Chen Y.T.
    J. Bacteriol. 194:6316-6316(2012) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 1084Imported.

Entry informationi

Entry nameiK4H908_KLEPN
AccessioniPrimary (citable) accession number: K4H908
Entry historyi
Integrated into UniProtKB/TrEMBL: January 9, 2013
Last sequence update: January 9, 2013
Last modified: October 29, 2014
This is version 14 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

External Data

Dasty 3