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K4H6X8

- K4H6X8_KLEPN

UniProt

K4H6X8 - K4H6X8_KLEPN

Protein

Thymidine kinase

Gene

A79E_2037

Organism
Klebsiella pneumoniae subsp. pneumoniae 1084
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 13 (01 Oct 2014)
      Sequence version 1 (09 Jan 2013)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    ATP + thymidine = ADP + thymidine 5'-phosphate.

    GO - Molecular functioni

    1. ATP binding Source: UniProtKB-KW
    2. thymidine kinase activity Source: UniProtKB-EC

    GO - Biological processi

    1. DNA replication Source: UniProtKB-KW

    Keywords - Molecular functioni

    KinaseUniRule annotationImported, Transferase

    Keywords - Biological processi

    DNA synthesisUniRule annotation

    Keywords - Ligandi

    ATP-bindingUniRule annotation, Nucleotide-binding

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Thymidine kinaseUniRule annotation (EC:2.7.1.21UniRule annotation)
    Gene namesi
    ORF Names:A79E_2037Imported
    OrganismiKlebsiella pneumoniae subsp. pneumoniae 1084Imported
    Taxonomic identifieri1193292 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeKlebsiella
    ProteomesiUP000009209: Chromosome

    Structurei

    3D structure databases

    ProteinModelPortaliK4H6X8.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the thymidine kinase family.UniRule annotation

    Phylogenomic databases

    KOiK00857.

    Family and domain databases

    InterProiIPR027417. P-loop_NTPase.
    IPR001267. Thymidine_kinase.
    IPR020633. Thymidine_kinase_CS.
    [Graphical view]
    PANTHERiPTHR11441. PTHR11441. 1 hit.
    PfamiPF00265. TK. 1 hit.
    [Graphical view]
    PIRSFiPIRSF035805. TK_cell. 1 hit.
    SUPFAMiSSF52540. SSF52540. 1 hit.
    PROSITEiPS00603. TK_CELLULAR_TYPE. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    K4H6X8-1 [UniParc]FASTAAdd to Basket

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    MRTVVYTAEI DDRFGAGKVS SRIGLSSPAR LYNPQTSLFD DIAAEHQLKP    50
    IHCVLVDESQ FLTREQVHEL SEVVDTLDIP VLCYGLRTDF RGELFTGSQY 100
    LLAWSDKLVE LKTICFCGRK ASMVLRLDQE GRPYNEGEQV VIGGNERYVS 150
    VCRKHYKEAL SVGSLTKVQN QHRPC 175
    Length:175
    Mass (Da):19,797
    Last modified:January 9, 2013 - v1
    Checksum:iCCE53167E903DE53
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP003785 Genomic DNA. Translation: AFQ65345.1.
    RefSeqiYP_006635836.1. NC_018522.1.

    Genome annotation databases

    EnsemblBacteriaiAFQ65345; AFQ65345; A79E_2037.
    GeneIDi13527019.
    KEGGikpp:A79E_2037.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP003785 Genomic DNA. Translation: AFQ65345.1 .
    RefSeqi YP_006635836.1. NC_018522.1.

    3D structure databases

    ProteinModelPortali K4H6X8.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AFQ65345 ; AFQ65345 ; A79E_2037 .
    GeneIDi 13527019.
    KEGGi kpp:A79E_2037.

    Phylogenomic databases

    KOi K00857.

    Family and domain databases

    InterProi IPR027417. P-loop_NTPase.
    IPR001267. Thymidine_kinase.
    IPR020633. Thymidine_kinase_CS.
    [Graphical view ]
    PANTHERi PTHR11441. PTHR11441. 1 hit.
    Pfami PF00265. TK. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF035805. TK_cell. 1 hit.
    SUPFAMi SSF52540. SSF52540. 1 hit.
    PROSITEi PS00603. TK_CELLULAR_TYPE. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Complete Genome Sequence of Klebsiella pneumoniae 1084, a Hypermucoviscosity-Negative K1 Clinical Strain."
      Lin A.C., Liao T.L., Lin Y.C., Lai Y.C., Lu M.C., Chen Y.T.
      J. Bacteriol. 194:6316-6316(2012) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: 1084Imported.

    Entry informationi

    Entry nameiK4H6X8_KLEPN
    AccessioniPrimary (citable) accession number: K4H6X8
    Entry historyi
    Integrated into UniProtKB/TrEMBL: January 9, 2013
    Last sequence update: January 9, 2013
    Last modified: October 1, 2014
    This is version 13 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteomeImported

    External Data

    Dasty 3