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K4H6X8

- K4H6X8_KLEPN

UniProt

K4H6X8 - K4H6X8_KLEPN

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Protein

Thymidine kinase

Gene

A79E_2037

Organism
Klebsiella pneumoniae subsp. pneumoniae 1084
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + thymidine = ADP + thymidine 5'-phosphate.UniRule annotation

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. thymidine kinase activity Source: UniProtKB-EC

GO - Biological processi

  1. DNA replication Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

KinaseUniRule annotationImported, Transferase

Keywords - Biological processi

DNA synthesisUniRule annotation

Keywords - Ligandi

ATP-bindingUniRule annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Thymidine kinaseUniRule annotation (EC:2.7.1.21UniRule annotation)
Gene namesi
ORF Names:A79E_2037Imported
OrganismiKlebsiella pneumoniae subsp. pneumoniae 1084Imported
Taxonomic identifieri1193292 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeKlebsiella
ProteomesiUP000009209: Chromosome

Structurei

3D structure databases

ProteinModelPortaliK4H6X8.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the thymidine kinase family.UniRule annotation

Phylogenomic databases

KOiK00857.

Family and domain databases

InterProiIPR027417. P-loop_NTPase.
IPR001267. Thymidine_kinase.
IPR020633. Thymidine_kinase_CS.
[Graphical view]
PANTHERiPTHR11441. PTHR11441. 1 hit.
PfamiPF00265. TK. 1 hit.
[Graphical view]
PIRSFiPIRSF035805. TK_cell. 1 hit.
SUPFAMiSSF52540. SSF52540. 1 hit.
PROSITEiPS00603. TK_CELLULAR_TYPE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

K4H6X8-1 [UniParc]FASTAAdd to Basket

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        10         20         30         40         50
MRTVVYTAEI DDRFGAGKVS SRIGLSSPAR LYNPQTSLFD DIAAEHQLKP
60 70 80 90 100
IHCVLVDESQ FLTREQVHEL SEVVDTLDIP VLCYGLRTDF RGELFTGSQY
110 120 130 140 150
LLAWSDKLVE LKTICFCGRK ASMVLRLDQE GRPYNEGEQV VIGGNERYVS
160 170
VCRKHYKEAL SVGSLTKVQN QHRPC
Length:175
Mass (Da):19,797
Last modified:January 9, 2013 - v1
Checksum:iCCE53167E903DE53
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP003785 Genomic DNA. Translation: AFQ65345.1.
RefSeqiYP_006635836.1. NC_018522.1.

Genome annotation databases

EnsemblBacteriaiAFQ65345; AFQ65345; A79E_2037.
GeneIDi13527019.
KEGGikpp:A79E_2037.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP003785 Genomic DNA. Translation: AFQ65345.1 .
RefSeqi YP_006635836.1. NC_018522.1.

3D structure databases

ProteinModelPortali K4H6X8.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AFQ65345 ; AFQ65345 ; A79E_2037 .
GeneIDi 13527019.
KEGGi kpp:A79E_2037.

Phylogenomic databases

KOi K00857.

Family and domain databases

InterProi IPR027417. P-loop_NTPase.
IPR001267. Thymidine_kinase.
IPR020633. Thymidine_kinase_CS.
[Graphical view ]
PANTHERi PTHR11441. PTHR11441. 1 hit.
Pfami PF00265. TK. 1 hit.
[Graphical view ]
PIRSFi PIRSF035805. TK_cell. 1 hit.
SUPFAMi SSF52540. SSF52540. 1 hit.
PROSITEi PS00603. TK_CELLULAR_TYPE. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Complete Genome Sequence of Klebsiella pneumoniae 1084, a Hypermucoviscosity-Negative K1 Clinical Strain."
    Lin A.C., Liao T.L., Lin Y.C., Lai Y.C., Lu M.C., Chen Y.T.
    J. Bacteriol. 194:6316-6316(2012) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 1084Imported.

Entry informationi

Entry nameiK4H6X8_KLEPN
AccessioniPrimary (citable) accession number: K4H6X8
Entry historyi
Integrated into UniProtKB/TrEMBL: January 9, 2013
Last sequence update: January 9, 2013
Last modified: October 29, 2014
This is version 14 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

External Data

Dasty 3