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Protein

Alpha-amylase

Gene

Si006461m.g

Organism
Setaria italica (Foxtail millet) (Panicum italicum)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

Endohydrolysis of (1->4)-alpha-D-glucosidic linkages in polysaccharides containing three or more (1->4)-alpha-linked D-glucose units.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei202 – 2021NucleophileUniRule annotation
Active sitei227 – 2271Proton donorUniRule annotation

GO - Molecular functioni

  1. alpha-amylase activity Source: UniProtKB-EC
  2. calcium ion binding Source: InterPro

GO - Biological processi

  1. carbohydrate metabolic process Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

GlycosidaseUniRule annotation, Hydrolase

Keywords - Biological processi

Carbohydrate metabolismUniRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Alpha-amylaseUniRule annotation (EC:3.2.1.1UniRule annotation)
Gene namesi
Name:Si006461m.gImported
Synonyms:Si008671m.gImported
OrganismiSetaria italica (Foxtail millet) (Panicum italicum)Imported
Taxonomic identifieri4555 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaLiliopsidaPoalesPoaceaePACMAD cladePanicoideaePaniceaeSetaria
ProteomesiUP000004995: Unplaced

Family & Domainsi

Sequence similaritiesi

Belongs to the glycosyl hydrolase 13 family.UniRule annotation

Phylogenomic databases

InParanoidiK3XX03.
KOiK01176.
OMAiAVAEIWD.

Family and domain databases

Gene3Di2.60.40.1180. 1 hit.
3.20.20.80. 1 hit.
InterProiIPR012850. A-amylase_bs_C.
IPR013775. A-amylase_pln.
IPR006046. Alpha_amylase.
IPR015902. Glyco_hydro_13.
IPR013780. Glyco_hydro_13_b.
IPR006047. Glyco_hydro_13_cat_dom.
IPR006589. Glyco_hydro_13_sub_cat_dom.
IPR013781. Glyco_hydro_catalytic_dom.
IPR017853. Glycoside_hydrolase_SF.
[Graphical view]
PANTHERiPTHR10357. PTHR10357. 1 hit.
PfamiPF07821. Alpha-amyl_C2. 1 hit.
PF00128. Alpha-amylase. 1 hit.
[Graphical view]
PIRSFiPIRSF001028. Alph-amls_plant. 1 hit.
PRINTSiPR00110. ALPHAAMYLASE.
SMARTiSM00642. Aamy. 1 hit.
SM00810. Alpha-amyl_C2. 1 hit.
[Graphical view]
SUPFAMiSSF51445. SSF51445. 1 hit.

Sequencei

Sequence statusi: Complete.

K3XX03-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGMGSRHMCC LSTLLLLLGL SSGQVLFQGF NWESSKQTGG WYNNLMGKVD
60 70 80 90 100
DIAAAGVTHV WLPPPSHSVS SEGYMPGRLY DLDASKYGTA AELKSLIAAF
110 120 130 140 150
HDKGVQAVAD IVINHRCADY KDSRGIYCIF EGGTPDSRLD WRAHMICRDD
160 170 180 190 200
AKYSDGTGNL DTGADFPGAP DIDHLNDRVQ RELTEWMLWL KSDLGFDAWR
210 220 230 240 250
LDFARGYSAE VARVYINGTA PSFVVAEIWD KMVPAGDDGK PAYDQDPHRQ
260 270 280 290 300
ALVDWVDKVG GAASPATVFD FTTKGILNAA VEGELWRLID TEGKAPGVIG
310 320 330 340 350
WWPAKAVTFV DNHDTGSTQA QWPFPHDKVM QGYAYILTHP GNPCIFYDHF
360 370 380 390 400
FDWGFKDEIA ALVAVRKRNG ITPTSELTIL EHDGDAYVAE IDGKVIVKIG
410 420 430
SRYDLGHLIP VGFEVATHGK DYAVWEKGGS EEVTRA
Length:436
Mass (Da):47,997
Last modified:November 28, 2012 - v1
Checksum:iF3284ECA2D0BC407
GO

Sequence databases

RefSeqiXP_004966428.1. XM_004966371.1.
XP_004966429.1. XM_004966372.1.

Genome annotation databases

EnsemblPlantsiSi006461m; Si006461m; Si006461m.g.
Si008671m; Si008671m; Si008671m.g.
GeneIDi101782965.
101783371.
KEGGisita:101782965.
sita:101783371.

Cross-referencesi

Sequence databases

RefSeqiXP_004966428.1. XM_004966371.1.
XP_004966429.1. XM_004966372.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsiSi006461m; Si006461m; Si006461m.g.
Si008671m; Si008671m; Si008671m.g.
GeneIDi101782965.
101783371.
KEGGisita:101782965.
sita:101783371.

Phylogenomic databases

InParanoidiK3XX03.
KOiK01176.
OMAiAVAEIWD.

Family and domain databases

Gene3Di2.60.40.1180. 1 hit.
3.20.20.80. 1 hit.
InterProiIPR012850. A-amylase_bs_C.
IPR013775. A-amylase_pln.
IPR006046. Alpha_amylase.
IPR015902. Glyco_hydro_13.
IPR013780. Glyco_hydro_13_b.
IPR006047. Glyco_hydro_13_cat_dom.
IPR006589. Glyco_hydro_13_sub_cat_dom.
IPR013781. Glyco_hydro_catalytic_dom.
IPR017853. Glycoside_hydrolase_SF.
[Graphical view]
PANTHERiPTHR10357. PTHR10357. 1 hit.
PfamiPF07821. Alpha-amyl_C2. 1 hit.
PF00128. Alpha-amylase. 1 hit.
[Graphical view]
PIRSFiPIRSF001028. Alph-amls_plant. 1 hit.
PRINTSiPR00110. ALPHAAMYLASE.
SMARTiSM00642. Aamy. 1 hit.
SM00810. Alpha-amyl_C2. 1 hit.
[Graphical view]
SUPFAMiSSF51445. SSF51445. 1 hit.
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "Foxtail millet: a sequence-driven grass model system."
    Doust A.N., Kellogg E.A., Devos K.M., Bennetzen J.L.
    Plant Physiol. 149:137-141(2009) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Yugu1Imported.
  2. EnsemblPlants
    Submitted (OCT-2012) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: Yugu1Imported.

Entry informationi

Entry nameiK3XX03_SETIT
AccessioniPrimary (citable) accession number: K3XX03
Entry historyi
Integrated into UniProtKB/TrEMBL: November 28, 2012
Last sequence update: November 28, 2012
Last modified: February 4, 2015
This is version 14 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.