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Protein
Submitted name:

Isocitrate/isopropylmalate dehydrogenase

Gene

icd

Organism
Nitrososphaera gargensis (strain Ga9.2)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein inferred from homologyi

Functioni

GO - Molecular functioni

  1. isocitrate dehydrogenase (NAD+) activity Source: UniProtKB-EC
  2. magnesium ion binding Source: InterPro
  3. NAD binding Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

OxidoreductaseImported

Names & Taxonomyi

Protein namesi
Submitted name:
Isocitrate/isopropylmalate dehydrogenaseImported (EC:1.1.1.-Imported, EC:1.1.1.41Imported)
Gene namesi
Name:icdImported
Ordered Locus Names:Ngar_c25160Imported
OrganismiNitrososphaera gargensis (strain Ga9.2)Imported
Taxonomic identifieri1237085 [NCBI]
Taxonomic lineageiArchaeaThaumarchaeotaNitrososphaeralesNitrososphaeraceaeNitrososphaera
ProteomesiUP000008037 Componenti: Chromosome

Family & Domainsi

Sequence similaritiesi

Belongs to the isocitrate and isopropylmalate dehydrogenases family.UniRule annotation

Phylogenomic databases

KOiK00031.
OMAiEYPDIRT.

Family and domain databases

Gene3Di3.40.718.10. 1 hit.
InterProiIPR001804. Isocitrate/isopropylmalate_DH.
IPR024084. IsoPropMal-DH-like_dom.
[Graphical view]
PANTHERiPTHR11835. PTHR11835. 1 hit.
PfamiPF00180. Iso_dh. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

K0INI6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MASTKTAAVI RGDGTGPELV NAMIKVLKAC NSKVELVPCD AGSEWWEKNG
60 70 80 90 100
GTSYISPEVW KLLEESDACF KGPTTTVPVP NAPRSVAVSI RQKFELYANI
110 120 130 140 150
RPIKTYKNAE KQLDFVCVRE ATEGLYAGIE FKTSDDSAVA IRKTTRKGCD
160 170 180 190 200
RVAKAGFEVA KKRGFGKVYA ITKRNILKET DGIFWAAVEN AQKQFKNIQV
210 220 230 240 250
EEYYIDNMTQ QLVKNPERFN QSVLLSTNLF MDIVSECASG HVGSIGNVYS
260 270 280 290 300
GNYGDKYAMF EPAHGSAPKY AGQNKVNPVA TVLSGAWMVE YLGEKHISDA
310 320 330 340
IFKATEDVIN EGKYVTYDLG GSATLSQMAD QIAARAGKLL KK
Length:342
Mass (Da):37,503
Last modified:November 28, 2012 - v1
Checksum:iAEF1A53C54FEAEDB
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP002408 Genomic DNA. Translation: AFU59439.1.
RefSeqiYP_006863096.1. NC_018719.1.

Genome annotation databases

EnsemblBacteriaiAFU59439; AFU59439; Ngar_c25160.
GeneIDi13794534.
KEGGinga:Ngar_c25160.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP002408 Genomic DNA. Translation: AFU59439.1.
RefSeqiYP_006863096.1. NC_018719.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAFU59439; AFU59439; Ngar_c25160.
GeneIDi13794534.
KEGGinga:Ngar_c25160.

Phylogenomic databases

KOiK00031.
OMAiEYPDIRT.

Family and domain databases

Gene3Di3.40.718.10. 1 hit.
InterProiIPR001804. Isocitrate/isopropylmalate_DH.
IPR024084. IsoPropMal-DH-like_dom.
[Graphical view]
PANTHERiPTHR11835. PTHR11835. 1 hit.
PfamiPF00180. Iso_dh. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "The genome of the ammonia-oxidizing Candidatus Nitrososphaera gargensis: insights into metabolic versatility and environmental adaptations."
    Spang A., Poehlein A., Offre P., Zumbragel S., Haider S., Rychlik N., Nowka B., Schmeisser C., Lebedeva E.V., Rattei T., Bohm C., Schmid M., Galushko A., Hatzenpichler R., Weinmaier T., Daniel R., Schleper C., Spieck E., Streit W., Wagner M.
    Environ. Microbiol. 14:3122-3145(2011) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Ga9.2Imported.

Entry informationi

Entry nameiK0INI6_NITGG
AccessioniPrimary (citable) accession number: K0INI6
Entry historyi
Integrated into UniProtKB/TrEMBL: November 28, 2012
Last sequence update: November 28, 2012
Last modified: January 7, 2015
This is version 12 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.