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K0HW25 (K0HW25_PROAA) Unreviewed, UniProtKB/TrEMBL

Last modified April 16, 2014. Version 10. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order

Protein attributes

Sequence length216 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + thymidine = ADP + thymidine 5'-phosphate. SAAS SAAS020634 HAMAP-Rule MF_00124

Subunit structure

Homotetramer By similarity. HAMAP-Rule MF_00124

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00124.

Sequence similarities

Belongs to the thymidine kinase family. HAMAP-Rule MF_00124

Ontologies

Keywords
   Biological processDNA synthesis HAMAP-Rule MF_00124 SAAS SAAS020634
   Cellular componentCytoplasm HAMAP-Rule MF_00124
   LigandATP-binding HAMAP-Rule MF_00124 SAAS SAAS020634
Nucleotide-binding
   Molecular functionKinase HAMAP-Rule MF_00124 SAAS SAAS020634 EMBL AFU40856.1
Transferase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processDNA replication

Inferred from electronic annotation. Source: UniProtKB-KW

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionATP binding

Inferred from electronic annotation. Source: UniProtKB-HAMAP

thymidine kinase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Nucleotide binding9 – 168ATP By similarity HAMAP-Rule MF_00124
Nucleotide binding86 – 894ATP By similarity HAMAP-Rule MF_00124

Sites

Active site871Proton acceptor By similarity HAMAP-Rule MF_00124

Sequences

Sequence LengthMass (Da)Tools
K0HW25 [UniParc].

Last modified November 28, 2012. Version 1.
Checksum: F6055E1F110118C5

FASTA21623,926
        10         20         30         40         50         60 
MAELVFHTGP MDSGKSTLAL QMDHAQSAHD RQGVRYAMHD RSGGARITSR IGLSVEAVEV 

        70         80         90        100        110        120 
TDSLDLYQDI VSRLSRGGRI DYLICDEAQF YRTKQIDQLA RVVDDLDIDV YCFGILADFR 

       130        140        150        160        170        180 
TELFPGSKRL VELADRVVEP PVSPLCWCGR PATHNARIVD GKLVREGDQV GVGDIGGGSE 

       190        200        210 
IHYEVLCRRH HRQGITGEIS RATLSEQTLP FDGSRS 

« Hide

References

[1]"Complete Genome Sequence of a Propionibacterium acnes Isolate from a Sarcoidosis Patient."
Minegishi K., Aikawa C., Furukawa A., Watanabe T., Nakano T., Ogura Y., Ohtsubo Y., Kurokawa K., Hayashi T., Maruyama F., Nakagawa I., Eishi Y.
Genome Announc. 1:E00016-12(2013) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE.
Strain: C1 EMBL AFU40856.1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP003877 Genomic DNA. Translation: AFU40856.1.
RefSeqYP_006851087.1. NC_018707.1.

3D structure databases

ProteinModelPortalK0HW25.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAFU40856; AFU40856; PAC1_05505.
GeneID13783090.
KEGGpacc:PAC1_05505.

Organism-specific databases

CMRSearch...

Phylogenomic databases

KOK00857.

Family and domain databases

HAMAPMF_00124. Thymidine_kinase.
InterProIPR027417. P-loop_NTPase.
IPR001267. Thymidine_kinase.
IPR020634. Thymidine_kinase_subgr.
[Graphical view]
PfamPF00265. TK. 1 hit.
[Graphical view]
PIRSFPIRSF035805. TK_cell. 1 hit.
SUPFAMSSF52540. SSF52540. 1 hit.
ProtoNetSearch...

Entry information

Entry nameK0HW25_PROAA
AccessionPrimary (citable) accession number: K0HW25
Entry history
Integrated into UniProtKB/TrEMBL: November 28, 2012
Last sequence update: November 28, 2012
Last modified: April 16, 2014
This is version 10 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)