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K0HSB2

- K0HSB2_CAMJU

UniProt

K0HSB2 - K0HSB2_CAMJU

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Protein
Submitted name: Isocitrate dehydrogenase
Gene
A911_02585
Organism
Campylobacter jejuni subsp. jejuni PT14
Status
Unreviewed - Annotation score: 2 out of 5 - Protein predictedi

Functioni

Cofactori

Binds 1 magnesium or manganese ion per subunit By similarity.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei142 – 1421Substrate By similarityUniRule annotation
Sitei252 – 2521Critical for catalysis By similarityUniRule annotation
Metal bindingi345 – 3451Magnesium or manganese By similarityUniRule annotation
Sitei415 – 4151Critical for catalysis By similarityUniRule annotation
Binding sitei538 – 5381Substrate By similarityUniRule annotation
Metal bindingi539 – 5391Magnesium or manganese By similarityUniRule annotation
Metal bindingi543 – 5431Magnesium or manganese By similarityUniRule annotation

GO - Molecular functioni

  1. isocitrate dehydrogenase (NADP+) activity Source: UniProtKB-EC
  2. metal ion binding Source: UniProtKB-KW

GO - Biological processi

  1. tricarboxylic acid cycle Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

OxidoreductaseImported

Keywords - Ligandi

MagnesiumUniRule annotation, Metal-bindingUniRule annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Isocitrate dehydrogenaseImported (EC:1.1.1.42Imported)
Gene namesi
ORF Names:A911_02585Imported
OrganismiCampylobacter jejuni subsp. jejuni PT14Imported
Taxonomic identifieri1201032 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaEpsilonproteobacteriaCampylobacteralesCampylobacteraceaeCampylobacter
ProteomesiUP000006307: Chromosome

Family & Domainsi

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni129 – 1368Substrate binding By similarityUniRule annotation

Phylogenomic databases

KOiK00031.

Family and domain databases

Gene3Di3.40.718.10. 3 hits.
InterProiIPR004436. Isocitrate_DH_NADP_mono.
IPR024084. IsoPropMal-DH-like_dom.
[Graphical view]
PfamiPF03971. IDH. 1 hit.
[Graphical view]
PIRSFiPIRSF009407. IDH_monmr. 1 hit.
TIGRFAMsiTIGR00178. monomer_idh. 1 hit.

Sequencei

Sequence statusi: Complete.

K0HSB2-1 [UniParc]FASTAAdd to Basket

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MQITYTLTDE SPALATYSFL PIVKAFLSRA HIGVKTSDIS LSGRILATFS    50
EYLKEEQRCE DALELLGELV KRSDANLIKT PNISASIPQL KAAIKELQDK 100
GYMLPNYPDE PKNDEELQIK TKYQKVLGSA VNPVLRQGNS DRRSTKAVKD 150
YAKNNPYRVV EFNPNSKTRV SYMKEGDFFS NEKAVLIDQD CVANIEFTSV 200
DGKKEILKEG LKLEKNEILD ATFMDVQKLQ EFYAKEIKAS KDDDVLFSLH 250
LKATMMKVSD PILFGYAVKV FFKELFIEFQ DEFEKLGINP NNGLSELLSK 300
IENSSKKDEI LKKYNEILAK SADISMVNSD KGITNLHVPS DVIVDASMPA 350
MLKNGARLWD KEGKEKDTNA VIPDQTYATI YEAVIEDLHK NGTLNPSKLG 400
SVSNVGLMAK KAQEYGSHDK TFVAKEEGTF KIVSNGKVLL EHKVRKGDIY 450
RANQAKFDAV LNWIDLGIER SELSGAEAIF WLDSKRASNK IMITLVQNRL 500
KEKGKNVAIL TPKEACLRSL ELIREGKDVI SITGNVLRDY LTDLFPILEL 550
GTSAKMLSVV PMLNGGAMFE TGAGGSAPKQ VEQLVEENHL RWDSLGEFLA 600
LQASLEFYVN KCGNHKAKVL AECLDEAIGE WLENNKAPSR KVKEDDNRTS 650
HFYLAMYFAN HLARQASDME LQSFFKDIAL ELSSNEEKIR AEFNDAQGVK 700
VDLGGYYKFD DEKANKIMRP SATFNAILEK IGQR 734
Length:734
Mass (Da):82,386
Last modified:November 28, 2012 - v1
Checksum:i0EF7141282A4ED03
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP003871 Genomic DNA. Translation: AFU42635.1.
RefSeqiYP_006857608.1. NC_018709.2.

Genome annotation databases

EnsemblBacteriaiAFU42635; AFU42635; A911_02585.
GeneIDi13790217.
KEGGicjp:A911_02585.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP003871 Genomic DNA. Translation: AFU42635.1 .
RefSeqi YP_006857608.1. NC_018709.2.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AFU42635 ; AFU42635 ; A911_02585 .
GeneIDi 13790217.
KEGGi cjp:A911_02585.

Phylogenomic databases

KOi K00031.

Family and domain databases

Gene3Di 3.40.718.10. 3 hits.
InterProi IPR004436. Isocitrate_DH_NADP_mono.
IPR024084. IsoPropMal-DH-like_dom.
[Graphical view ]
Pfami PF03971. IDH. 1 hit.
[Graphical view ]
PIRSFi PIRSF009407. IDH_monmr. 1 hit.
TIGRFAMsi TIGR00178. monomer_idh. 1 hit.
ProtoNeti Search...

Publicationsi

  1. "Complete Genome Sequence of Universal Bacteriophage Host Strain Campylobacter jejuni subsp. jejuni PT14."
    Brathwaite K.J., Siringan P., Moreton J., Wilson R., Connerton I.F.
    Genome Announc. 1:e00969-13(2013) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: PT14Imported.

Entry informationi

Entry nameiK0HSB2_CAMJU
AccessioniPrimary (citable) accession number: K0HSB2
Entry historyi
Integrated into UniProtKB/TrEMBL: November 28, 2012
Last sequence update: November 28, 2012
Last modified: September 3, 2014
This is version 11 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome

External Data

Dasty 3

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