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K0HSB2

- K0HSB2_CAMJU

UniProt

K0HSB2 - K0HSB2_CAMJU

Protein
Submitted name:

Isocitrate dehydrogenase

Gene

A911_02585

Organism
Campylobacter jejuni subsp. jejuni PT14
Status
Unreviewed - Annotation score: 1 out of 5- Protein predictedi
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    • History
      Entry version 12 (01 Oct 2014)
      Sequence version 1 (28 Nov 2012)
      Previous versions | rss
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    Functioni

    Cofactori

    Binds 1 magnesium or manganese ion per subunit.UniRule annotation

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Binding sitei142 – 1421SubstrateUniRule annotation
    Sitei252 – 2521Critical for catalysisUniRule annotation
    Metal bindingi345 – 3451Magnesium or manganese
    Sitei415 – 4151Critical for catalysisUniRule annotation
    Binding sitei538 – 5381SubstrateUniRule annotation
    Metal bindingi539 – 5391Magnesium or manganese
    Metal bindingi543 – 5431Magnesium or manganese

    GO - Molecular functioni

    1. isocitrate dehydrogenase (NADP+) activity Source: UniProtKB-EC
    2. metal ion binding Source: UniProtKB-KW

    GO - Biological processi

    1. tricarboxylic acid cycle Source: InterPro

    Keywords - Molecular functioni

    OxidoreductaseImported

    Keywords - Ligandi

    MagnesiumUniRule annotation, Metal-bindingUniRule annotation

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Isocitrate dehydrogenaseImported (EC:1.1.1.42Imported)
    Gene namesi
    ORF Names:A911_02585Imported
    OrganismiCampylobacter jejuni subsp. jejuni PT14Imported
    Taxonomic identifieri1201032 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaEpsilonproteobacteriaCampylobacteralesCampylobacteraceaeCampylobacter
    ProteomesiUP000006307: Chromosome

    Family & Domainsi

    Region

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Regioni129 – 1368Substrate bindingUniRule annotation

    Phylogenomic databases

    KOiK00031.

    Family and domain databases

    Gene3Di3.40.718.10. 3 hits.
    InterProiIPR004436. Isocitrate_DH_NADP_mono.
    IPR024084. IsoPropMal-DH-like_dom.
    [Graphical view]
    PfamiPF03971. IDH. 1 hit.
    [Graphical view]
    PIRSFiPIRSF009407. IDH_monmr. 1 hit.
    TIGRFAMsiTIGR00178. monomer_idh. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    K0HSB2-1 [UniParc]FASTAAdd to Basket

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    MQITYTLTDE SPALATYSFL PIVKAFLSRA HIGVKTSDIS LSGRILATFS    50
    EYLKEEQRCE DALELLGELV KRSDANLIKT PNISASIPQL KAAIKELQDK 100
    GYMLPNYPDE PKNDEELQIK TKYQKVLGSA VNPVLRQGNS DRRSTKAVKD 150
    YAKNNPYRVV EFNPNSKTRV SYMKEGDFFS NEKAVLIDQD CVANIEFTSV 200
    DGKKEILKEG LKLEKNEILD ATFMDVQKLQ EFYAKEIKAS KDDDVLFSLH 250
    LKATMMKVSD PILFGYAVKV FFKELFIEFQ DEFEKLGINP NNGLSELLSK 300
    IENSSKKDEI LKKYNEILAK SADISMVNSD KGITNLHVPS DVIVDASMPA 350
    MLKNGARLWD KEGKEKDTNA VIPDQTYATI YEAVIEDLHK NGTLNPSKLG 400
    SVSNVGLMAK KAQEYGSHDK TFVAKEEGTF KIVSNGKVLL EHKVRKGDIY 450
    RANQAKFDAV LNWIDLGIER SELSGAEAIF WLDSKRASNK IMITLVQNRL 500
    KEKGKNVAIL TPKEACLRSL ELIREGKDVI SITGNVLRDY LTDLFPILEL 550
    GTSAKMLSVV PMLNGGAMFE TGAGGSAPKQ VEQLVEENHL RWDSLGEFLA 600
    LQASLEFYVN KCGNHKAKVL AECLDEAIGE WLENNKAPSR KVKEDDNRTS 650
    HFYLAMYFAN HLARQASDME LQSFFKDIAL ELSSNEEKIR AEFNDAQGVK 700
    VDLGGYYKFD DEKANKIMRP SATFNAILEK IGQR 734
    Length:734
    Mass (Da):82,386
    Last modified:November 28, 2012 - v1
    Checksum:i0EF7141282A4ED03
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP003871 Genomic DNA. Translation: AFU42635.1.
    RefSeqiYP_006857608.1. NC_018709.2.

    Genome annotation databases

    EnsemblBacteriaiAFU42635; AFU42635; A911_02585.
    GeneIDi13790217.
    KEGGicjp:A911_02585.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP003871 Genomic DNA. Translation: AFU42635.1 .
    RefSeqi YP_006857608.1. NC_018709.2.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AFU42635 ; AFU42635 ; A911_02585 .
    GeneIDi 13790217.
    KEGGi cjp:A911_02585.

    Phylogenomic databases

    KOi K00031.

    Family and domain databases

    Gene3Di 3.40.718.10. 3 hits.
    InterProi IPR004436. Isocitrate_DH_NADP_mono.
    IPR024084. IsoPropMal-DH-like_dom.
    [Graphical view ]
    Pfami PF03971. IDH. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF009407. IDH_monmr. 1 hit.
    TIGRFAMsi TIGR00178. monomer_idh. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "Complete Genome Sequence of Universal Bacteriophage Host Strain Campylobacter jejuni subsp. jejuni PT14."
      Brathwaite K.J., Siringan P., Moreton J., Wilson R., Connerton I.F.
      Genome Announc. 1:e00969-13(2013) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: PT14Imported.

    Entry informationi

    Entry nameiK0HSB2_CAMJU
    AccessioniPrimary (citable) accession number: K0HSB2
    Entry historyi
    Integrated into UniProtKB/TrEMBL: November 28, 2012
    Last sequence update: November 28, 2012
    Last modified: October 1, 2014
    This is version 12 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteomeImported

    External Data

    Dasty 3