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K0HN77 (K0HN77_PROAA) Unreviewed, UniProtKB/TrEMBL

Last modified July 9, 2014. Version 13. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Protein attributes

Sequence length375 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Function

Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids By similarity. HAMAP-Rule MF_01201

Catalytic activity

L-alanine = D-alanine. RuleBase RU004247 SAAS SAAS020622 HAMAP-Rule MF_01201

Cofactor

Pyridoxal phosphate By similarity. SAAS SAAS020622 HAMAP-Rule MF_01201

Pathway

Amino-acid biosynthesis; D-alanine biosynthesis; D-alanine from L-alanine: step 1/1. RuleBase RU004247 HAMAP-Rule MF_01201

Sequence similarities

Belongs to the alanine racemase family. RuleBase RU004188 HAMAP-Rule MF_01201

Ontologies

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Active site381Proton acceptor; specific for D-alanine By similarity HAMAP-Rule MF_01201
Active site2661Proton acceptor; specific for L-alanine By similarity HAMAP-Rule MF_01201
Binding site1371Substrate By similarity HAMAP-Rule MF_01201
Binding site3141Substrate; via amide nitrogen By similarity HAMAP-Rule MF_01201

Amino acid modifications

Modified residue381N6-(pyridoxal phosphate)lysine By similarity HAMAP-Rule MF_01201

Sequences

Sequence LengthMass (Da)Tools
K0HN77 [UniParc].

Last modified November 28, 2012. Version 1.
Checksum: C56EBAE89371B404

FASTA37540,162
        10         20         30         40         50         60 
MPRCPSPSHA IIDLSAIAAN LAVVRKRAGD RKVLFAVKAD AYGHGAVEVS RYVEKHRYAD 

        70         80         90        100        110        120 
WLAVATVAEG QELVEAGITL PILKLSPAHP WDMDAAITSG IRLTVVDFDT LEAVSKAAVR 

       130        140        150        160        170        180 
LGITAKIHIA VDSGMGRIGL RPECLAELTA AADRAKGVEV EGVFTHLPIS DVPEGAEFTR 

       190        200        210        220        230        240 
REIDTFMTAV SLIETHRGPF PLVHLANSGA ILGHDLGKTS MVRAGIVGYG YDPNPHADRA 

       250        260        270        280        290        300 
DLHPALSWIS HVTFVKTVSV GDTIGYGRTW TASETTKIAT VPVGYADGLS RGLSNKGHVL 

       310        320        330        340        350        360 
IRGSVHPIVG RICMDQFMVD LGPDSNVTVG DEVVLIGTQE DETLTADDMA ELLGTISYEI 

       370 
TCAISKRVDR YWVGQ 

« Hide

References

[1]"Complete Genome Sequence of a Propionibacterium acnes Isolate from a Sarcoidosis Patient."
Minegishi K., Aikawa C., Furukawa A., Watanabe T., Nakano T., Ogura Y., Ohtsubo Y., Kurokawa K., Hayashi T., Maruyama F., Nakagawa I., Eishi Y.
Genome Announc. 1:E00016-12(2013) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE.
Strain: C1 EMBL AFU42067.1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP003877 Genomic DNA. Translation: AFU42067.1.
RefSeqYP_006852298.1. NC_018707.1.

3D structure databases

ProteinModelPortalK0HN77.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAFU42067; AFU42067; PAC1_11655.
GeneID13784339.
KEGGpacc:PAC1_11655.

Organism-specific databases

CMRSearch...

Phylogenomic databases

KOK01775.

Enzyme and pathway databases

UniPathwayUPA00042; UER00497.

Family and domain databases

Gene3D2.40.37.10. 1 hit.
3.20.20.10. 1 hit.
HAMAPMF_01201. Ala_racemase.
InterProIPR000821. Ala_racemase.
IPR009006. Ala_racemase/Decarboxylase_C.
IPR011079. Ala_racemase_C.
IPR001608. Ala_racemase_N.
IPR020622. Ala_racemase_pyridoxalP-BS.
IPR029066. PLP-binding_barrel.
[Graphical view]
PfamPF00842. Ala_racemase_C. 1 hit.
PF01168. Ala_racemase_N. 1 hit.
[Graphical view]
PRINTSPR00992. ALARACEMASE.
SMARTSM01005. Ala_racemase_C. 1 hit.
[Graphical view]
SUPFAMSSF50621. SSF50621. 1 hit.
SSF51419. SSF51419. 1 hit.
TIGRFAMsTIGR00492. alr. 1 hit.
PROSITEPS00395. ALANINE_RACEMASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameK0HN77_PROAA
AccessionPrimary (citable) accession number: K0HN77
Entry history
Integrated into UniProtKB/TrEMBL: November 28, 2012
Last sequence update: November 28, 2012
Last modified: July 9, 2014
This is version 13 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)