Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

K0ETG7

- K0ETG7_9NOCA

UniProt

K0ETG7 - K0ETG7_9NOCA

Protein

Alanine racemase

Gene

alr

Organism
Nocardia brasiliensis ATCC 700358
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 14 (01 Oct 2014)
      Sequence version 1 (28 Nov 2012)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.UniRule annotation

    Catalytic activityi

    L-alanine = D-alanine.UniRule annotation

    Cofactori

    Pyridoxal phosphate.UniRule annotationSAAS annotation

    Pathwayi

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei31 – 311Proton acceptor; specific for D-alanineUniRule annotation
    Binding sitei129 – 1291SubstrateUniRule annotation
    Active sitei258 – 2581Proton acceptor; specific for L-alanineUniRule annotation
    Binding sitei306 – 3061Substrate; via amide nitrogenUniRule annotation

    GO - Molecular functioni

    1. alanine racemase activity Source: UniProtKB-HAMAP
    2. pyridoxal phosphate binding Source: UniProtKB-HAMAP

    GO - Biological processi

    1. D-alanine biosynthetic process Source: UniProtKB-UniPathway

    Keywords - Molecular functioni

    IsomeraseUniRule annotationSAAS annotationImported

    Keywords - Ligandi

    Pyridoxal phosphateUniRule annotationSAAS annotation

    Enzyme and pathway databases

    UniPathwayiUPA00042; UER00497.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Alanine racemaseUniRule annotation (EC:5.1.1.1UniRule annotation)
    Gene namesi
    Name:alrImported
    ORF Names:O3I_004990Imported
    OrganismiNocardia brasiliensis ATCC 700358Imported
    Taxonomic identifieri1133849 [NCBI]
    Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeActinomycetalesCorynebacterineaeNocardiaceaeNocardia
    ProteomesiUP000006304: Chromosome

    PTM / Processingi

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Modified residuei31 – 311N6-(pyridoxal phosphate)lysineUniRule annotation

    Structurei

    3D structure databases

    ProteinModelPortaliK0ETG7.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the alanine racemase family.UniRule annotation

    Phylogenomic databases

    KOiK01775.

    Family and domain databases

    Gene3Di2.40.37.10. 1 hit.
    3.20.20.10. 1 hit.
    HAMAPiMF_01201. Ala_racemase.
    InterProiIPR000821. Ala_racemase.
    IPR009006. Ala_racemase/Decarboxylase_C.
    IPR011079. Ala_racemase_C.
    IPR001608. Ala_racemase_N.
    IPR029066. PLP-binding_barrel.
    [Graphical view]
    PfamiPF00842. Ala_racemase_C. 1 hit.
    PF01168. Ala_racemase_N. 1 hit.
    [Graphical view]
    PRINTSiPR00992. ALARACEMASE.
    SMARTiSM01005. Ala_racemase_C. 1 hit.
    [Graphical view]
    SUPFAMiSSF50621. SSF50621. 1 hit.
    SSF51419. SSF51419. 1 hit.
    TIGRFAMsiTIGR00492. alr. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    K0ETG7-1 [UniParc]FASTAAdd to Basket

    « Hide

    METVVDLDAI AHNVRILREL AGDAAVMAVV KADGYNHGAV EVGKAALAAG    50
    AAELGVTTIA EAVRLREAGI TAPILSWLNN SAADYAAAIG ADIEIGVSSL 100
    DHLRAVAAAT EQTGRTATVS LKVDTGLNRN GLSPVEYPQA LAELRTLVDA 150
    QAMRFRALFS HLANADEPAH PVNDMQRDRF LEAIAVAKEH GLEPELVHLA 200
    NSPATLTRPD LAFDMVRPGI AMYGHSPVAE DFGLRPAMTF QARVALVKQV 250
    AAGEGVSYGH TWYAPRDTTV ALIPVGYADG VFRPLSGRFE VWLGGARRPN 300
    VGRVCMDQFV VDLGDNAANV REGDMAVLFG GGPGEPRAQE WADLLGTIHY 350
    EVVCSPRGRS VRRYVGGGR 369
    Length:369
    Mass (Da):39,203
    Last modified:November 28, 2012 - v1
    Checksum:iAADE0AB67DF4ABB5
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP003876 Genomic DNA. Translation: AFT98960.1.
    RefSeqiWP_014981817.1. NC_018681.1.
    YP_006805935.1. NC_018681.1.

    Genome annotation databases

    EnsemblBacteriaiAFT98960; AFT98960; O3I_004990.
    GeneIDi13734076.
    KEGGinbr:O3I_004990.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP003876 Genomic DNA. Translation: AFT98960.1 .
    RefSeqi WP_014981817.1. NC_018681.1.
    YP_006805935.1. NC_018681.1.

    3D structure databases

    ProteinModelPortali K0ETG7.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AFT98960 ; AFT98960 ; O3I_004990 .
    GeneIDi 13734076.
    KEGGi nbr:O3I_004990.

    Phylogenomic databases

    KOi K01775.

    Enzyme and pathway databases

    UniPathwayi UPA00042 ; UER00497 .

    Family and domain databases

    Gene3Di 2.40.37.10. 1 hit.
    3.20.20.10. 1 hit.
    HAMAPi MF_01201. Ala_racemase.
    InterProi IPR000821. Ala_racemase.
    IPR009006. Ala_racemase/Decarboxylase_C.
    IPR011079. Ala_racemase_C.
    IPR001608. Ala_racemase_N.
    IPR029066. PLP-binding_barrel.
    [Graphical view ]
    Pfami PF00842. Ala_racemase_C. 1 hit.
    PF01168. Ala_racemase_N. 1 hit.
    [Graphical view ]
    PRINTSi PR00992. ALARACEMASE.
    SMARTi SM01005. Ala_racemase_C. 1 hit.
    [Graphical view ]
    SUPFAMi SSF50621. SSF50621. 1 hit.
    SSF51419. SSF51419. 1 hit.
    TIGRFAMsi TIGR00492. alr. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: HUJEG-1Imported.

    Entry informationi

    Entry nameiK0ETG7_9NOCA
    AccessioniPrimary (citable) accession number: K0ETG7
    Entry historyi
    Integrated into UniProtKB/TrEMBL: November 28, 2012
    Last sequence update: November 28, 2012
    Last modified: October 1, 2014
    This is version 14 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3