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K0ETG7 (K0ETG7_9NOCA) Unreviewed, UniProtKB/TrEMBL

Last modified May 29, 2013. Version 5. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Alanine racemase HAMAP-Rule MF_01201
EC=5.1.1.1 HAMAP-Rule MF_01201
Gene names
Name:alr EMBL AFT98960.1
ORF Names:O3I_004990 EMBL AFT98960.1
OrganismNocardia brasiliensis ATCC 700358 EMBL AFT98960.1
Taxonomic identifier1133849 [NCBI]
Taxonomic lineageBacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Nocardiaceae › Nocardia ›

Protein attributes

Sequence length369 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids By similarity. HAMAP-Rule MF_01201

Catalytic activity

L-alanine = D-alanine. HAMAP-Rule MF_01201

Cofactor

Pyridoxal phosphate By similarity. HAMAP-Rule MF_01201 SAAS SAAS000821

Pathway

Amino-acid biosynthesis; D-alanine biosynthesis; D-alanine from L-alanine: step 1/1. HAMAP-Rule MF_01201

Sequence similarities

Belongs to the alanine racemase family. HAMAP-Rule MF_01201 RuleBase RU004188

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Active site311Proton acceptor; specific for D-alanine By similarity HAMAP-Rule MF_01201
Active site2581Proton acceptor; specific for L-alanine By similarity HAMAP-Rule MF_01201
Binding site1291Substrate By similarity HAMAP-Rule MF_01201
Binding site3061Substrate; via amide nitrogen By similarity HAMAP-Rule MF_01201

Amino acid modifications

Modified residue311N6-(pyridoxal phosphate)lysine By similarity HAMAP-Rule MF_01201

Sequences

Sequence LengthMass (Da)Tools
K0ETG7 [UniParc].

Last modified November 28, 2012. Version 1.
Checksum: AADE0AB67DF4ABB5

FASTA36939,203
        10         20         30         40         50         60 
METVVDLDAI AHNVRILREL AGDAAVMAVV KADGYNHGAV EVGKAALAAG AAELGVTTIA 

        70         80         90        100        110        120 
EAVRLREAGI TAPILSWLNN SAADYAAAIG ADIEIGVSSL DHLRAVAAAT EQTGRTATVS 

       130        140        150        160        170        180 
LKVDTGLNRN GLSPVEYPQA LAELRTLVDA QAMRFRALFS HLANADEPAH PVNDMQRDRF 

       190        200        210        220        230        240 
LEAIAVAKEH GLEPELVHLA NSPATLTRPD LAFDMVRPGI AMYGHSPVAE DFGLRPAMTF 

       250        260        270        280        290        300 
QARVALVKQV AAGEGVSYGH TWYAPRDTTV ALIPVGYADG VFRPLSGRFE VWLGGARRPN 

       310        320        330        340        350        360 
VGRVCMDQFV VDLGDNAANV REGDMAVLFG GGPGEPRAQE WADLLGTIHY EVVCSPRGRS 


VRRYVGGGR

« Hide

References

[1]"Complete genome sequence of Nocardia brasiliensis HUJEG-1."
Vera-Cabrera L., Ortiz-Lopez R., Elizondo-Gonzalez R., Perez-Maya A.A., Ocampo-Candiani J.
J. Bacteriol. 194:2761-2762(2012) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE.
Strain: HUJEG-1 EMBL AFT98960.1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP003876 Genomic DNA. Translation: AFT98960.1.
RefSeqYP_006805935.1. NC_018681.1.

3D structure databases

ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAFT98960; AFT98960; O3I_004990.
GeneID13734076.
KEGGnbr:O3I_004990.

Phylogenomic databases

KOK01775.

Enzyme and pathway databases

UniPathwayUPA00042; UER00497.

Family and domain databases

Gene3D2.40.37.10. 1 hit.
HAMAPMF_01201. Ala_racemase.
InterProIPR000821. Ala_racemase.
IPR009006. Ala_racemase/Decarboxylase_C.
IPR011079. Ala_racemase_C.
IPR001608. Ala_racemase_N.
[Graphical view]
PfamPF00842. Ala_racemase_C. 1 hit.
PF01168. Ala_racemase_N. 1 hit.
[Graphical view]
PRINTSPR00992. ALARACEMASE.
SMARTSM01005. Ala_racemase_C. 1 hit.
[Graphical view]
SUPFAMSSF50621. Racem_decarbox_C. 1 hit.
TIGRFAMsTIGR00492. alr. 1 hit.
ProtoNetSearch...

Entry information

Entry nameK0ETG7_9NOCA
AccessionPrimary (citable) accession number: K0ETG7
Entry history
Integrated into UniProtKB/TrEMBL: November 28, 2012
Last sequence update: November 28, 2012
Last modified: May 29, 2013
This is version 5 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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