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K0ETG7

- K0ETG7_9NOCA

UniProt

K0ETG7 - K0ETG7_9NOCA

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Protein

Alanine racemase

Gene

alr

Organism
Nocardia brasiliensis ATCC 700358
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.UniRule annotation

Catalytic activityi

L-alanine = D-alanine.UniRule annotation

Cofactori

Pyridoxal phosphate.UniRule annotationSAAS annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei31 – 311Proton acceptor; specific for D-alanineUniRule annotation
Binding sitei129 – 1291SubstrateUniRule annotation
Active sitei258 – 2581Proton acceptor; specific for L-alanineUniRule annotation
Binding sitei306 – 3061Substrate; via amide nitrogenUniRule annotation

GO - Molecular functioni

  1. alanine racemase activity Source: UniProtKB-HAMAP
  2. pyridoxal phosphate binding Source: UniProtKB-HAMAP

GO - Biological processi

  1. D-alanine biosynthetic process Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

IsomeraseUniRule annotationSAAS annotation

Keywords - Ligandi

Pyridoxal phosphateUniRule annotationSAAS annotation

Enzyme and pathway databases

UniPathwayiUPA00042; UER00497.

Names & Taxonomyi

Protein namesi
Recommended name:
Alanine racemaseUniRule annotation (EC:5.1.1.1UniRule annotation)
Gene namesi
Name:alrImported
ORF Names:O3I_004990Imported
OrganismiNocardia brasiliensis ATCC 700358Imported
Taxonomic identifieri1133849 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeActinomycetalesCorynebacterineaeNocardiaceaeNocardia
ProteomesiUP000006304: Chromosome

PTM / Processingi

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei31 – 311N6-(pyridoxal phosphate)lysineUniRule annotation

Structurei

3D structure databases

ProteinModelPortaliK0ETG7.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the alanine racemase family.UniRule annotation

Phylogenomic databases

KOiK01775.

Family and domain databases

Gene3Di2.40.37.10. 1 hit.
3.20.20.10. 1 hit.
HAMAPiMF_01201. Ala_racemase.
InterProiIPR000821. Ala_racemase.
IPR009006. Ala_racemase/Decarboxylase_C.
IPR011079. Ala_racemase_C.
IPR001608. Ala_racemase_N.
IPR029066. PLP-binding_barrel.
[Graphical view]
PfamiPF00842. Ala_racemase_C. 1 hit.
PF01168. Ala_racemase_N. 1 hit.
[Graphical view]
PRINTSiPR00992. ALARACEMASE.
SMARTiSM01005. Ala_racemase_C. 1 hit.
[Graphical view]
SUPFAMiSSF50621. SSF50621. 1 hit.
SSF51419. SSF51419. 1 hit.
TIGRFAMsiTIGR00492. alr. 1 hit.

Sequencei

Sequence statusi: Complete.

K0ETG7-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
METVVDLDAI AHNVRILREL AGDAAVMAVV KADGYNHGAV EVGKAALAAG
60 70 80 90 100
AAELGVTTIA EAVRLREAGI TAPILSWLNN SAADYAAAIG ADIEIGVSSL
110 120 130 140 150
DHLRAVAAAT EQTGRTATVS LKVDTGLNRN GLSPVEYPQA LAELRTLVDA
160 170 180 190 200
QAMRFRALFS HLANADEPAH PVNDMQRDRF LEAIAVAKEH GLEPELVHLA
210 220 230 240 250
NSPATLTRPD LAFDMVRPGI AMYGHSPVAE DFGLRPAMTF QARVALVKQV
260 270 280 290 300
AAGEGVSYGH TWYAPRDTTV ALIPVGYADG VFRPLSGRFE VWLGGARRPN
310 320 330 340 350
VGRVCMDQFV VDLGDNAANV REGDMAVLFG GGPGEPRAQE WADLLGTIHY
360
EVVCSPRGRS VRRYVGGGR
Length:369
Mass (Da):39,203
Last modified:November 28, 2012 - v1
Checksum:iAADE0AB67DF4ABB5
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP003876 Genomic DNA. Translation: AFT98960.1.
RefSeqiWP_014981817.1. NC_018681.1.
YP_006805935.1. NC_018681.1.

Genome annotation databases

EnsemblBacteriaiAFT98960; AFT98960; O3I_004990.
GeneIDi13734076.
KEGGinbr:O3I_004990.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP003876 Genomic DNA. Translation: AFT98960.1 .
RefSeqi WP_014981817.1. NC_018681.1.
YP_006805935.1. NC_018681.1.

3D structure databases

ProteinModelPortali K0ETG7.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AFT98960 ; AFT98960 ; O3I_004990 .
GeneIDi 13734076.
KEGGi nbr:O3I_004990.

Phylogenomic databases

KOi K01775.

Enzyme and pathway databases

UniPathwayi UPA00042 ; UER00497 .

Family and domain databases

Gene3Di 2.40.37.10. 1 hit.
3.20.20.10. 1 hit.
HAMAPi MF_01201. Ala_racemase.
InterProi IPR000821. Ala_racemase.
IPR009006. Ala_racemase/Decarboxylase_C.
IPR011079. Ala_racemase_C.
IPR001608. Ala_racemase_N.
IPR029066. PLP-binding_barrel.
[Graphical view ]
Pfami PF00842. Ala_racemase_C. 1 hit.
PF01168. Ala_racemase_N. 1 hit.
[Graphical view ]
PRINTSi PR00992. ALARACEMASE.
SMARTi SM01005. Ala_racemase_C. 1 hit.
[Graphical view ]
SUPFAMi SSF50621. SSF50621. 1 hit.
SSF51419. SSF51419. 1 hit.
TIGRFAMsi TIGR00492. alr. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: HUJEG-1Imported.

Entry informationi

Entry nameiK0ETG7_9NOCA
AccessioniPrimary (citable) accession number: K0ETG7
Entry historyi
Integrated into UniProtKB/TrEMBL: November 28, 2012
Last sequence update: November 28, 2012
Last modified: October 29, 2014
This is version 15 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3