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Protein

Phosphoenolpyruvate carboxylase

Gene

ppc

Organism
Nocardia brasiliensis ATCC 700358
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.UniRule annotationSAAS annotation

Catalytic activityi

Phosphate + oxaloacetate = H2O + phosphoenolpyruvate + HCO3-.UniRule annotationSAAS annotation

Cofactori

Mg2+UniRule annotationSAAS annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei149 – 1491UniRule annotation
Active sitei585 – 5851UniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

LyaseUniRule annotationSAAS annotation

Keywords - Biological processi

Carbon dioxide fixationUniRule annotationSAAS annotation

Keywords - Ligandi

MagnesiumUniRule annotationSAAS annotation, PyruvateImported

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoenolpyruvate carboxylaseUniRule annotationSAAS annotation (EC:4.1.1.31UniRule annotationSAAS annotation)
Short name:
PEPCUniRule annotation
Short name:
PEPCaseUniRule annotation
Gene namesi
Name:ppcUniRule annotation
ORF Names:O3I_013180Imported
OrganismiNocardia brasiliensis ATCC 700358Imported
Taxonomic identifieri1133849 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaCorynebacterialesNocardiaceaeNocardia
ProteomesiUP000006304 Componenti: Chromosome

Interactioni

Subunit structurei

Homotetramer.UniRule annotation

Family & Domainsi

Sequence similaritiesi

Belongs to the PEPCase type 1 family.UniRule annotation

Phylogenomic databases

KOiK01595.

Family and domain databases

HAMAPiMF_00595. PEPcase_type1.
InterProiIPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view]
PfamiPF00311. PEPcase. 1 hit.
[Graphical view]
PRINTSiPR00150. PEPCARBXLASE.
SUPFAMiSSF51621. SSF51621. 1 hit.
PROSITEiPS00781. PEPCASE_1. 1 hit.
PS00393. PEPCASE_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

K0ESY9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGESTSEAQQ DAIRPLRDDI RFLGGVLGDT IRDHEGPEVF DLIEQVRIEA
60 70 80 90 100
FRVRRAEVDR SAVAEMLDGV DIAVALPLIR AFSYFVLLAN LAEDIQRDRR
110 120 130 140 150
RAAHEAAGEP PQDSSLAATY RKLDAAALDG AEVADLLADA LVSPVITAHP
160 170 180 190 200
TETRRRTVFD AQTRITELMR LRQRYTETER QRADFEQQIR RQVLSLWRTA
210 220 230 240 250
LIRLARLRIQ DEISVGLRYY DITLFDVIPA INAEVRAALR SRWPGVELLP
260 270 280 290 300
RPILRPGSWI GGDRDGNPYV TADVVRQAGQ QAATVAFSRY LRDLVELEKV
310 320 330 340 350
LALSVRLVPV TPAVAALAEA GYPEPATHAD EPYRRALHRI RGRLTATAVR
360 370 380 390 400
ALGEVPADGL DVGAEPYRTP QDVLDDLDAV DASLRASGDD LLADHRLAAL
410 420 430 440 450
RHAIETFGFH LQGLDMRQNS EIHEQVVAEL LAWAGVHADY ASLSEPERVE
460 470 480 490 500
LLAAELRTRR PLLGPHARLS ELARKEVDIV CAARDVVSTF GSEAVPNYII
510 520 530 540 550
SMCTSVSDML EAALLLKEGG LLDPGEPDGP PSCAVGIVPL FETIEDLAAG
560 570 580 590 600
AATLSAALDV PVYRDLVAAR GMRQEVMLGY SDSNKDGGYL AANWALYRAE
610 620 630 640 650
LELVEVARKS GIRLRLFHGR GGTVGRGGGR SYDAILAQPA GAVRGALRLT
660 670 680 690 700
EQGEVIAAKY AEPGAAHRNL ESLIAGTLES TLLDVEGLGP DAEPSYELMD
710 720 730 740 750
ELAERARAAY ARLVHDTPGF VEYFRQSTPV AEVGDLNIGS RPASRKPTNS
760 770 780 790 800
VADLRAIPWV MSWSQARVML PGWYGTGTAL EEWIGDDPQR LATLTDLYER
810 820 830 840 850
WPFFRTVLSN LAQVLAKSDL AIAARYAELV DDVALREQIF GMIKDEHART
860 870 880 890 900
IRMHAAVTGN DHLLADNPSL AESIHNRFPY LEPLNQMQVQ LLRRLRAGDD
910 920
SELVKRGILL TMNGLATALR NSG
Length:923
Mass (Da):101,363
Last modified:November 28, 2012 - v1
Checksum:iAA4CC828370A2740
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP003876 Genomic DNA. Translation: AFU00597.1.

Genome annotation databases

EnsemblBacteriaiAFU00597; AFU00597; O3I_013180.
KEGGinbr:O3I_013180.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP003876 Genomic DNA. Translation: AFU00597.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAFU00597; AFU00597; O3I_013180.
KEGGinbr:O3I_013180.

Phylogenomic databases

KOiK01595.

Family and domain databases

HAMAPiMF_00595. PEPcase_type1.
InterProiIPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view]
PfamiPF00311. PEPcase. 1 hit.
[Graphical view]
PRINTSiPR00150. PEPCARBXLASE.
SUPFAMiSSF51621. SSF51621. 1 hit.
PROSITEiPS00781. PEPCASE_1. 1 hit.
PS00393. PEPCASE_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: HUJEG-1Imported.

Entry informationi

Entry nameiK0ESY9_9NOCA
AccessioniPrimary (citable) accession number: K0ESY9
Entry historyi
Integrated into UniProtKB/TrEMBL: November 28, 2012
Last sequence update: November 28, 2012
Last modified: July 22, 2015
This is version 22 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.