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Protein

Phosphoenolpyruvate carboxylase

Gene

ppc

Organism
Alteromonas macleodii (strain Balearic Sea AD45)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.UniRule annotationSAAS annotation

Catalytic activityi

Phosphate + oxaloacetate = H2O + phosphoenolpyruvate + HCO3-.UniRule annotationSAAS annotation

Cofactori

Mg2+UniRule annotationSAAS annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei133 – 1331UniRule annotation
Active sitei538 – 5381UniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

LyaseUniRule annotationSAAS annotation

Keywords - Biological processi

Carbon dioxide fixationUniRule annotationSAAS annotation

Keywords - Ligandi

MagnesiumUniRule annotationSAAS annotation, PyruvateImported

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoenolpyruvate carboxylaseUniRule annotationSAAS annotation (EC:4.1.1.31UniRule annotationSAAS annotation)
Short name:
PEPCUniRule annotation
Short name:
PEPCaseUniRule annotation
Gene namesi
Name:ppcUniRule annotation
Ordered Locus Names:AMBAS45_16775Imported
OrganismiAlteromonas macleodii (strain Balearic Sea AD45)Imported
Taxonomic identifieri1004787 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaAlteromonadalesAlteromonadaceaeAlteromonas
ProteomesiUP000006308 Componenti: Chromosome

Interactioni

Subunit structurei

Homotetramer.UniRule annotation

Family & Domainsi

Sequence similaritiesi

Belongs to the PEPCase type 1 family.UniRule annotation

Phylogenomic databases

KOiK01595.
OMAiWGFAVIE.

Family and domain databases

HAMAPiMF_00595. PEPcase_type1.
InterProiIPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view]
PfamiPF00311. PEPcase. 1 hit.
[Graphical view]
PRINTSiPR00150. PEPCARBXLASE.
SUPFAMiSSF51621. SSF51621. 1 hit.
PROSITEiPS00781. PEPCASE_1. 1 hit.
PS00393. PEPCASE_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

K0EK95-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MQTHYDAELK DTVRYLGKTL GETIKNQLGQ EWLDRIEKIR KGGRASYQGD
60 70 80 90 100
ATCSEELKET FKTMSDSDLL TVGRAFAQFL NLGNIAEQEY NAAMNVDASI
110 120 130 140 150
DALFKHLDKA ELTAEKVQDA VAKLNIDLVL TAHPTEVTRR TLIHKHKELA
160 170 180 190 200
NCLQAIHQES LSDVERKKIE TRIADLIAQA WHTEEIRSVR PTPVDEARWG
210 220 230 240 250
FSVIENSLWE AVPDFMRELD GRLNEDYDVS LPLDSSPVQF SSWMGGDRDG
260 270 280 290 300
NPFVTSKVTE QVLLLARKRA AKLFAIDLDR LQVELSMYDC NDALREKVGD
310 320 330 340 350
ANEPYRALLR PLVDKFITTR DGISDYLAGK NPDTSNWVES DDELIEPLML
360 370 380 390 400
CYQSLLDCGM QVVANGLLLD TIRRARVFGI HLLRLDVRQD SERHADVFSE
410 420 430 440 450
LTRYLGLGDY AQWSEADKQA FLLRELGSKR PLFPAQWDAS DDVKEVLDTC
460 470 480 490 500
KVIAKHSKHG FGIYIISMAS EPSDVMAVQL LLQESGVDWP MPVAPLFETL
510 520 530 540 550
DDLNNSPDVM RKLLSIDWYR GYVKGRQFVM IGYSDSAKDA GALAAGWAQY
560 570 580 590 600
QSQEALVAIA DEFDVSLTLF HGRGGTIGRG GLPAHAAIYS QPPGSLDGGF
610 620 630 640 650
RVTEQGETIR YKFGMPKLAK RSLGIYASAI IEAMLFPPPA PKEEWRELIT
660 670 680 690 700
AMAAQGRDNY RATVRHDKEF VPYFRVATPE QELGKLPLGS RPAKRKPQGG
710 720 730 740 750
IESLRAIPWI FAWAQTRLVL PSWLGVMRAI DSVKTPENEK VVNEMFSEWP
760 770 780 790 800
FYRSRLSMLD MVFHKADPRI SEAYDERLVP KELKHFGEAL RSELKESISS
810 820 830 840 850
LLAITGDGDI MKNDPQGKES MEIRAGYLQP LHYLQIELLD RIRKAGDDAQ
860 870
NTSLERAMMV TIAGIAIGMR NTG
Length:873
Mass (Da):98,207
Last modified:November 28, 2012 - v1
Checksum:i9E0C088827E0CFA2
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP003873 Genomic DNA. Translation: AFT96814.1.
RefSeqiWP_014980368.1. NC_018679.1.

Genome annotation databases

EnsemblBacteriaiAFT96814; AFT96814; AMBAS45_16775.
KEGGiamb:AMBAS45_16775.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP003873 Genomic DNA. Translation: AFT96814.1.
RefSeqiWP_014980368.1. NC_018679.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAFT96814; AFT96814; AMBAS45_16775.
KEGGiamb:AMBAS45_16775.

Phylogenomic databases

KOiK01595.
OMAiWGFAVIE.

Family and domain databases

HAMAPiMF_00595. PEPcase_type1.
InterProiIPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view]
PfamiPF00311. PEPcase. 1 hit.
[Graphical view]
PRINTSiPR00150. PEPCARBXLASE.
SUPFAMiSSF51621. SSF51621. 1 hit.
PROSITEiPS00781. PEPCASE_1. 1 hit.
PS00393. PEPCASE_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Genomes of surface isolates of Alteromonas macleodii: the life of a widespread marine opportunistic copiotroph."
    Lopez-Perez M., Gonzaga A., Martin-Cuadrado A.B., Onyshchenko O., Ghavidel A., Ghai R., Rodriguez-Valera F.
    Sci. Rep. 2:696-696(2012) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Balearic Sea AD45Imported.

Entry informationi

Entry nameiK0EK95_ALTMB
AccessioniPrimary (citable) accession number: K0EK95
Entry historyi
Integrated into UniProtKB/TrEMBL: November 28, 2012
Last sequence update: November 28, 2012
Last modified: July 22, 2015
This is version 20 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.