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K0C4Y6

- K0C4Y6_CYCSP

UniProt

K0C4Y6 - K0C4Y6_CYCSP

Protein
Submitted name:

Isocitrate dehydrogenase

Gene

Q91_1570

Organism
Cycloclasticus sp. (strain P1)
Status
Unreviewed - Annotation score: 1 out of 5- Protein predictedi
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    • History
      Entry version 11 (01 Oct 2014)
      Sequence version 1 (28 Nov 2012)
      Previous versions | rss
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    Functioni

    Cofactori

    Binds 1 magnesium or manganese ion per subunit.UniRule annotation

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Binding sitei147 – 1471SubstrateUniRule annotation
    Sitei257 – 2571Critical for catalysisUniRule annotation
    Metal bindingi352 – 3521Magnesium or manganese
    Sitei422 – 4221Critical for catalysisUniRule annotation
    Binding sitei549 – 5491SubstrateUniRule annotation
    Metal bindingi550 – 5501Magnesium or manganese
    Metal bindingi554 – 5541Magnesium or manganese

    GO - Molecular functioni

    1. isocitrate dehydrogenase (NADP+) activity Source: InterPro
    2. metal ion binding Source: UniProtKB-KW

    GO - Biological processi

    1. tricarboxylic acid cycle Source: InterPro

    Keywords - Ligandi

    MagnesiumUniRule annotation, Metal-bindingUniRule annotation

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Isocitrate dehydrogenaseImported
    Gene namesi
    Ordered Locus Names:Q91_1570Imported
    OrganismiCycloclasticus sp. (strain P1)Imported
    Taxonomic identifieri385025 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaThiotrichalesPiscirickettsiaceaeCycloclasticus
    ProteomesiUP000006282: Chromosome

    Family & Domainsi

    Region

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Regioni134 – 1418Substrate bindingUniRule annotation

    Phylogenomic databases

    KOiK00031.

    Family and domain databases

    Gene3Di3.40.718.10. 3 hits.
    InterProiIPR004436. Isocitrate_DH_NADP_mono.
    IPR024084. IsoPropMal-DH-like_dom.
    [Graphical view]
    PfamiPF03971. IDH. 1 hit.
    [Graphical view]
    PIRSFiPIRSF009407. IDH_monmr. 1 hit.
    TIGRFAMsiTIGR00178. monomer_idh. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    K0C4Y6-1 [UniParc]FASTAAdd to Basket

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    MTVKKSKIIY TLTDEAPLLA TASFLPIVEA FAGAAGIDVE VSDISLASRV    50
    LATFADQLPD DQKVPDALSE LGRLTQNPET NIIKLPNISA SVPQLKAIIN 100
    ELQGKGFDIP NYPEDPQTDE EKALQQKYGK VLGSAVNPVL REGNSDRRAP 150
    KAVKEYAKKN PHSMGKWSQA SRTHVSHMRS GDFYSSEKSL TLDKACKVNI 200
    EFVAKNGEVT VLKKGLALQE GEIIDSMFMS KKQLCAYLED EMNDAKETGV 250
    MFSFHVKATM MKVSHPIVFG HAVKVYYKDL FEKHGKLFDE LGVNPNDGLS 300
    SVYEHIEKLP ASIKEEILSD MHACYEKRPE LAMVDSAKGI SNLHTPNEVI 350
    VDASMPAMIR AGGKMWGPDG KMKDTKAVMP ESTFARIYQE IINFCKTHGE 400
    FDPTTMGTVP NVGLMAQKAE EYGSHDKTFE MKADGSTRIV DEEGNVLLEM 450
    DVEEGDIWRM CQVKDAPIQD WVKLAVKRAR LSNTPAVFWL DKYRPHENEL 500
    IKKVEKYLKD HDLTGVDIKI KSQTRAMRYT LERILRGKDT ISVTGNILRD 550
    YLTDLFPILE LGTSAKMLSI VPLMAGGGLF ETGAGGSAPK HVKQLIEENH 600
    LRWDSLGEFL ALCASLEHTA ISDDNAKAAV LAKTLDEATA KLLDTGKSPS 650
    RKTGELDNRG SHFYLALYWA QALAEQTEDE ALQAHFQPLA ASLTENEEKI 700
    VGTLTTEQWH AVDIGGYYKP DVDKVREVMR PSEIFNEALA SLK 743
    Length:743
    Mass (Da):82,427
    Last modified:November 28, 2012 - v1
    Checksum:iC6EC019216DC833D
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP003230 Genomic DNA. Translation: AFT67605.1.
    RefSeqiYP_006838108.1. NC_018697.1.

    Genome annotation databases

    EnsemblBacteriaiAFT67605; AFT67605; Q91_1570.
    GeneIDi13772762.
    KEGGicyq:Q91_1570.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP003230 Genomic DNA. Translation: AFT67605.1 .
    RefSeqi YP_006838108.1. NC_018697.1.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AFT67605 ; AFT67605 ; Q91_1570 .
    GeneIDi 13772762.
    KEGGi cyq:Q91_1570.

    Phylogenomic databases

    KOi K00031.

    Family and domain databases

    Gene3Di 3.40.718.10. 3 hits.
    InterProi IPR004436. Isocitrate_DH_NADP_mono.
    IPR024084. IsoPropMal-DH-like_dom.
    [Graphical view ]
    Pfami PF03971. IDH. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF009407. IDH_monmr. 1 hit.
    TIGRFAMsi TIGR00178. monomer_idh. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "Complete genome sequence of the pyrene-degrading bacterium Cycloclasticus sp. strain P1."
      Lai Q., Li W., Wang B., Yu Z., Shao Z.
      J. Bacteriol. 194:6677-6677(2012) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: P1Imported.

    Entry informationi

    Entry nameiK0C4Y6_CYCSP
    AccessioniPrimary (citable) accession number: K0C4Y6
    Entry historyi
    Integrated into UniProtKB/TrEMBL: November 28, 2012
    Last sequence update: November 28, 2012
    Last modified: October 1, 2014
    This is version 11 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3