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Protein

Elongation factor Tu

Gene

tuf1

Organism
Clostridium acidurici (strain ATCC 7906 / DSM 604 / KCTC 5404 / 9a)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.UniRule annotation

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi19 – 268GTPUniRule annotation
Nucleotide bindingi82 – 865GTPUniRule annotation
Nucleotide bindingi137 – 1404GTPUniRule annotation

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

Elongation factorUniRule annotationImported

Keywords - Biological processi

Protein biosynthesis

Keywords - Ligandi

GTP-bindingUniRule annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Elongation factor TuUniRule annotation
Short name:
EF-TuUniRule annotation
Gene namesi
Name:tuf1Imported
Synonyms:tufUniRule annotation, tuf2Imported
Ordered Locus Names:Curi_c22650Imported, Curi_c22790Imported
OrganismiClostridium acidurici (strain ATCC 7906 / DSM 604 / KCTC 5404 / 9a)Imported
Taxonomic identifieri1128398 [NCBI]
Taxonomic lineageiBacteriaFirmicutesClostridiaClostridialesGottschalkia
ProteomesiUP000006094 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

CytoplasmUniRule annotation

Interactioni

Subunit structurei

Monomer.UniRule annotation

Family & Domainsi

Sequence similaritiesi

Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.UniRule annotation

Phylogenomic databases

KOiK02358.
OMAiGMVICKP.

Family and domain databases

Gene3Di3.40.50.300. 1 hit.
HAMAPiMF_00118_B. EF_Tu_B.
InterProiIPR031157. G_TR_CS.
IPR027417. P-loop_NTPase.
IPR005225. Small_GTP-bd_dom.
IPR000795. TF_GTP-bd_dom.
IPR009000. Transl_B-barrel.
IPR009001. Transl_elong_EF1A/Init_IF2_C.
IPR004161. Transl_elong_EFTu/EF1A_2.
IPR004541. Transl_elong_EFTu/EF1A_bac/org.
IPR004160. Transl_elong_EFTu/EF1A_C.
[Graphical view]
PfamiPF03144. GTP_EFTU_D2. 1 hit.
PF03143. GTP_EFTU_D3. 1 hit.
[Graphical view]
PRINTSiPR00315. ELONGATNFCT.
SUPFAMiSSF50447. SSF50447. 1 hit.
SSF50465. SSF50465. 1 hit.
SSF52540. SSF52540. 1 hit.
TIGRFAMsiTIGR00485. EF-Tu. 1 hit.
TIGR00231. small_GTP. 1 hit.
PROSITEiPS00301. G_TR_1. 1 hit.
PS51722. G_TR_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

K0AZP3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGKAKFERSK PHVNIGTIGH VDHGKTTLTA AITTVLHARL GTGEGIAYDN
60 70 80 90 100
IDKAPEERER GITISTSHVE YETENRHYAH VDCPGHADYV KNMITGAAQM
110 120 130 140 150
DGAILVCSAA DGPMPQTREH ILLSRQVGVP TIVVFLNKAD MVNDEELIEL
160 170 180 190 200
VEMEVRELLS EYEFDGDNTP IVVGSALKAL EDPSSEWGDK ILELMAAVDE
210 220 230 240 250
TIPTPERDTD KAFLMPVEDI FSITGRGTVA TGKVERGVLK VQDNVEIVGI
260 270 280 290 300
AEESRTVVCT GIEMFRKLLD DAQAGDNIGA LLRGVQREDI QRGQVLAKPG
310 320 330 340 350
SITPHTHFEA EVYVLNKEEG GRHTPFFDGY RPQFYFRTTD VTGSIKLEEG
360 370 380 390
VEMVMPGDNA KFTIELISPI AMEEGLRFAV REGGRTVGSG VISKILK
Length:397
Mass (Da):43,486
Last modified:November 28, 2012 - v1
Checksum:i868B3C7DA3BCE40D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP003326 Genomic DNA. Translation: AFS79268.1.
CP003326 Genomic DNA. Translation: AFS79282.1.
RefSeqiWP_014968404.1. NC_018664.1.

Genome annotation databases

EnsemblBacteriaiAFS79268; AFS79268; Curi_c22650.
AFS79282; AFS79282; Curi_c22790.
KEGGicad:Curi_c22650.
cad:Curi_c22790.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP003326 Genomic DNA. Translation: AFS79268.1.
CP003326 Genomic DNA. Translation: AFS79282.1.
RefSeqiWP_014968404.1. NC_018664.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAFS79268; AFS79268; Curi_c22650.
AFS79282; AFS79282; Curi_c22790.
KEGGicad:Curi_c22650.
cad:Curi_c22790.

Phylogenomic databases

KOiK02358.
OMAiGMVICKP.

Family and domain databases

Gene3Di3.40.50.300. 1 hit.
HAMAPiMF_00118_B. EF_Tu_B.
InterProiIPR031157. G_TR_CS.
IPR027417. P-loop_NTPase.
IPR005225. Small_GTP-bd_dom.
IPR000795. TF_GTP-bd_dom.
IPR009000. Transl_B-barrel.
IPR009001. Transl_elong_EF1A/Init_IF2_C.
IPR004161. Transl_elong_EFTu/EF1A_2.
IPR004541. Transl_elong_EFTu/EF1A_bac/org.
IPR004160. Transl_elong_EFTu/EF1A_C.
[Graphical view]
PfamiPF03144. GTP_EFTU_D2. 1 hit.
PF03143. GTP_EFTU_D3. 1 hit.
[Graphical view]
PRINTSiPR00315. ELONGATNFCT.
SUPFAMiSSF50447. SSF50447. 1 hit.
SSF50465. SSF50465. 1 hit.
SSF52540. SSF52540. 1 hit.
TIGRFAMsiTIGR00485. EF-Tu. 1 hit.
TIGR00231. small_GTP. 1 hit.
PROSITEiPS00301. G_TR_1. 1 hit.
PS51722. G_TR_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "The purine-utilizing bacterium Clostridium acidurici 9a: a genome-guided metabolic reconsideration."
    Hartwich K., Poehlein A., Daniel R.
    PLoS ONE 7:E51662-E51662(2012) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 9aImported and ATCC 7906 / DSM 604 / KCTC 5404 / 9aImported.

Entry informationi

Entry nameiK0AZP3_CLOA9
AccessioniPrimary (citable) accession number: K0AZP3
Entry historyi
Integrated into UniProtKB/TrEMBL: November 28, 2012
Last sequence update: November 28, 2012
Last modified: July 22, 2015
This is version 22 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.