K0APS1 (K0APS1_ECO1C) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Alanine racemase RuleBase RU000608
EC=5.1.1.1 RuleBase RU000608

Gene names

Name:	dadX EMBL AFS74822.1
Ordered Locus Names:	O3K_14710 EMBL AFS74822.1

Organism

Escherichia coli O104:H4 (strain 2011C-3493) [Complete proteome] [HAMAP] EMBL AFS74822.1

Taxonomic identifier

1133852 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Escherichia › Escherichia coli › Escherichia coli O104:H4

Protein attributes

Sequence length	356 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	L-alanine = D-alanine. SAAS SAAS020622 RuleBase RU000608
Cofactor	Pyridoxal phosphate By similarity. SAAS SAAS020622 RuleBase RU000608
Pathway	Amino-acid biosynthesis; D-alanine biosynthesis; D-alanine from L-alanine: step 1/1. SAAS SAAS020622
Sequence similarities	Belongs to the alanine racemase family. RuleBase RU004188

Ontologies

Keywords
Ligand	Pyridoxal phosphate SAAS SAAS020622 RuleBase RU000608
Molecular function	Isomerase SAAS SAAS020622 RuleBase RU000608 EMBL AFS74822.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	D-alanine biosynthetic process Inferred from electronic annotation. Source: UniProtKB-UniPathway
Molecular_function	alanine racemase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	K0APS1 [UniParc]. Last modified November 28, 2012. Version 1. Checksum: 817FAA44C8B3ED70	FASTA	356	38,871
	10 20 30 40 50 60 MTRPIQASLD LQALKQNLSI VRQAAPHARV WSVVKANAYG HGIERIWSAL GATDGFALLN 70 80 90 100 110 120 LEEAITLRER GWKGPILMLE GFFHAQDLEI YDQHRLTTCV HSNWQLKALQ NARLKAPLDI 130 140 150 160 170 180 YLKVNSGMNR LGFQPDRVLT VWQQLRAMAN VGEMTLMSHF AEAEHPDGIS SAMARIEQAA 190 200 210 220 230 240 EGLECRRSLS NSAATLWHPE AHFDWVRPGI ILYGASPSGQ WRDIANTGLR PVMTLSSEII 250 260 270 280 290 300 GVQTLKAGER VGYGGRYTAR DEQRIGIVAA GYADGYPRHA PTGTPVLVDG VRTMTVGTVS 310 320 330 340 350 MDMLAVDLTP CPQAGIGTPV ELWGKEIKID DVAAAAGTVG YELMCALALR VPVVTV

References

[1]

"Genomic comparison of Escherichia coli O104:H4 isolates from 2009 and 2011 reveals plasmid, and prophage heterogeneity, including Shiga toxin encoding phage stx2." Threat Characterization Consortium Ahmed S.A., Awosika J., Baldwin C., Bishop-Lilly K.A., Biswas B., Broomall S., Chain P.S., Chertkov O., Chokoshvili O., Coyne S., Davenport K., Detter J.C., Dorman W., Erkkila T.H., Folster J.P., Frey K.G., George M., Gleasner C. , Henry M., Hill K.K., Hubbard K., Insalaco J., Johnson S., Kitzmiller A., Krepps M., Lo C.C., Luu T., McNew L.A., Minogue T., Munk C.A., Osborne B., Patel M., Reitenga K.G., Rosenzweig C.N., Shea A., Shen X., Strockbine N., Tarr C., Teshima H., van Gieson E., Verratti K., Wolcott M., Xie G., Sozhamannan S., Gibbons H.S. PLoS ONE 7:E48228-E48228(2012) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: 2011C-3493 EMBL AFS74822.1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP003289 Genomic DNA. Translation: AFS74822.1.
RefSeq	YP_006779623.1. NC_018658.1.
3D structure databases
ProteinModelPortal	K0APS1.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	13700998.
KEGG	esl:O3K_14710.
Organism-specific databases
CMR	Search...
Phylogenomic databases
KO	K01775.
OMA	GQWQDIA.
Enzyme and pathway databases
UniPathway	UPA00042; UER00497.
Family and domain databases
Gene3D	2.40.37.10. 1 hit.
HAMAP	MF_01201. Ala_racemase.
InterPro	IPR000821. Ala_racemase. IPR009006. Ala_racemase/Decarboxylase_C. IPR011079. Ala_racemase_C. IPR001608. Ala_racemase_N. IPR020622. Ala_racemase_pyridoxalP-BS. [Graphical view]
Pfam	PF00842. Ala_racemase_C. 1 hit. PF01168. Ala_racemase_N. 1 hit. [Graphical view]
PRINTS	PR00992. ALARACEMASE.
SMART	SM01005. Ala_racemase_C. 1 hit. [Graphical view]
SUPFAM	SSF50621. Racem_decarbox_C. 1 hit.
TIGRFAMs	TIGR00492. alr. 1 hit.
PROSITE	PS00395. ALANINE_RACEMASE. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

K0APS1_ECO1C

Accession

Primary (citable) accession number: K0APS1

Entry history

Integrated into UniProtKB/TrEMBL:	November 28, 2012
Last sequence update:	November 28, 2012
Last modified:	March 6, 2013
This is version 4 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)