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K0AEU4

- K0AEU4_EXIAB

UniProt

K0AEU4 - K0AEU4_EXIAB

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Protein
Alanine racemase
Gene
alr2, Eab7_2619
Organism
Exiguobacterium antarcticum (strain B7)
Status
Unreviewed - Annotation score: 2 out of 5 - Experimental evidence at protein leveli

Functioni

Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids By similarity.UniRule annotation

Catalytic activityi

L-alanine = D-alanine.UniRule annotationSAAS annotations

Cofactori

Pyridoxal phosphate By similarity.UniRule annotationSAAS annotations

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei35 – 351Proton acceptor; specific for D-alanine By similarityUniRule annotation
Binding sitei132 – 1321Substrate By similarityUniRule annotation
Active sitei259 – 2591Proton acceptor; specific for L-alanine By similarityUniRule annotation
Binding sitei306 – 3061Substrate; via amide nitrogen By similarityUniRule annotation

GO - Molecular functioni

  1. alanine racemase activity Source: UniProtKB-HAMAP
  2. pyridoxal phosphate binding Source: UniProtKB-HAMAP

GO - Biological processi

  1. D-alanine biosynthetic process Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

IsomeraseUniRule annotationSAAS annotations

Keywords - Ligandi

Pyridoxal phosphateUniRule annotationSAAS annotations

Enzyme and pathway databases

UniPathwayiUPA00042; UER00497.

Names & Taxonomyi

Protein namesi
Recommended name:
Alanine racemaseUniRule annotation (EC:5.1.1.1UniRule annotation)
Gene namesi
Name:alr2Imported
Ordered Locus Names:Eab7_2619Imported
OrganismiExiguobacterium antarcticum (strain B7)Imported
Taxonomic identifieri1087448 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesBacillales Family XII. Incertae SedisExiguobacterium
ProteomesiUP000006274: Chromosome

PTM / Processingi

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei35 – 351N6-(pyridoxal phosphate)lysine By similarityUniRule annotation

Structurei

3D structure databases

ProteinModelPortaliK0AEU4.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

KOiK01775.

Family and domain databases

Gene3Di2.40.37.10. 1 hit.
3.20.20.10. 1 hit.
HAMAPiMF_01201. Ala_racemase.
InterProiIPR000821. Ala_racemase.
IPR009006. Ala_racemase/Decarboxylase_C.
IPR011079. Ala_racemase_C.
IPR001608. Ala_racemase_N.
IPR020622. Ala_racemase_pyridoxalP-BS.
IPR029066. PLP-binding_barrel.
[Graphical view]
PfamiPF00842. Ala_racemase_C. 1 hit.
PF01168. Ala_racemase_N. 1 hit.
[Graphical view]
PRINTSiPR00992. ALARACEMASE.
SMARTiSM01005. Ala_racemase_C. 1 hit.
[Graphical view]
SUPFAMiSSF50621. SSF50621. 1 hit.
SSF51419. SSF51419. 1 hit.
TIGRFAMsiTIGR00492. alr. 1 hit.
PROSITEiPS00395. ALANINE_RACEMASE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

K0AEU4-1 [UniParc]FASTAAdd to Basket

« Hide

MYRPTWIEID REAIAHNVRE IKARMGHQSM MAVVKADGYG HGAITVAEIA    50
LANGAEMLAV ALLEEAIELR EAGIQAPILM LEALLPEHAP IASNYDVAVP 100
VFSAEWLREA KQHLTEIDHL RLHIKVDSGM GRLGLQTLDE LDAVLKELDP 150
DLMELDGIYT HFATADELTS RLFEKQQTVF LRFVERVPGI RYIHASNSAA 200
AIRLAGQEPC NVVRIGIALY GALPSDEMSS YYDFLQPAFS LKSRLMQVKH 250
VEPGQTISYG ATYTAPTDEW IGTVPIGYAD GWSRKFQGYA LIVDGTPCEI 300
VGRVCMDRLM IRLPRAYPVG TEVTLIGRGA PIDEAAHWLG TINYEVLCQF 350
SKRVPRI 357
Length:357
Mass (Da):39,657
Last modified:November 28, 2012 - v1
Checksum:iD19F9829E9489A4F
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP003063 Genomic DNA. Translation: AFS71704.1.
RefSeqiWP_014971521.1. NC_018665.1.
YP_006792312.1. NC_018665.1.

Genome annotation databases

EnsemblBacteriaiAFS71704; AFS71704; Eab7_2619.
GeneIDi13713482.
KEGGiean:Eab7_2619.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP003063 Genomic DNA. Translation: AFS71704.1 .
RefSeqi WP_014971521.1. NC_018665.1.
YP_006792312.1. NC_018665.1.

3D structure databases

ProteinModelPortali K0AEU4.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AFS71704 ; AFS71704 ; Eab7_2619 .
GeneIDi 13713482.
KEGGi ean:Eab7_2619.

Phylogenomic databases

KOi K01775.

Enzyme and pathway databases

UniPathwayi UPA00042 ; UER00497 .

Family and domain databases

Gene3Di 2.40.37.10. 1 hit.
3.20.20.10. 1 hit.
HAMAPi MF_01201. Ala_racemase.
InterProi IPR000821. Ala_racemase.
IPR009006. Ala_racemase/Decarboxylase_C.
IPR011079. Ala_racemase_C.
IPR001608. Ala_racemase_N.
IPR020622. Ala_racemase_pyridoxalP-BS.
IPR029066. PLP-binding_barrel.
[Graphical view ]
Pfami PF00842. Ala_racemase_C. 1 hit.
PF01168. Ala_racemase_N. 1 hit.
[Graphical view ]
PRINTSi PR00992. ALARACEMASE.
SMARTi SM01005. Ala_racemase_C. 1 hit.
[Graphical view ]
SUPFAMi SSF50621. SSF50621. 1 hit.
SSF51419. SSF51419. 1 hit.
TIGRFAMsi TIGR00492. alr. 1 hit.
PROSITEi PS00395. ALANINE_RACEMASE. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: B7.

Entry informationi

Entry nameiK0AEU4_EXIAB
AccessioniPrimary (citable) accession number: K0AEU4
Entry historyi
Integrated into UniProtKB/TrEMBL: November 28, 2012
Last sequence update: November 28, 2012
Last modified: September 3, 2014
This is version 16 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome

External Data

Dasty 3

Similar proteinsi