ID   K0AAA4_EXIAB            Unreviewed;       321 AA.
AC   K0AAA4;
DT   28-NOV-2012, integrated into UniProtKB/TrEMBL.
DT   28-NOV-2012, sequence version 1.
DT   27-MAR-2024, entry version 57.
DE   SubName: Full=Alanine racemase {ECO:0000313|EMBL:AFS69626.1};
GN   Name=alr {ECO:0000313|EMBL:AFS69626.1};
GN   OrderedLocusNames=Eab7_0468 {ECO:0000313|EMBL:AFS69626.1};
OS   Exiguobacterium antarcticum (strain B7).
OC   Bacteria; Bacillota; Bacilli; Bacillales;
OC   Bacillales Family XII. Incertae Sedis; Exiguobacterium.
OX   NCBI_TaxID=1087448 {ECO:0000313|EMBL:AFS69626.1, ECO:0000313|Proteomes:UP000006274};
RN   [1] {ECO:0000313|EMBL:AFS69626.1, ECO:0000313|Proteomes:UP000006274}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=B7 {ECO:0000313|Proteomes:UP000006274};
RX   PubMed=23144424; DOI=10.1128/JB.01791-12;
RA   Carneiro A.R., Ramos R.T., Dall'Agnol H., Pinto A.C., de Castro Soares S.,
RA   Santos A.R., Guimaraes L.C., Almeida S.S., Barauna R.A., das Gracas D.A.,
RA   Franco L.C., Ali A., Hassan S.S., Nunes C.I., Barbosa M.S., Fiaux K.K.,
RA   Aburjaile F.F., Barbosa E.G., Bakhtiar S.M., Vilela D., Nobrega F.,
RA   Dos Santos A.L., Carepo M.S., Azevedo V., Schneider M.P., Pellizari V.H.,
RA   Silva A.;
RT   "Genome sequence of Exiguobacterium antarcticum B7, isolated from a biofilm
RT   in Ginger Lake, King George Island, Antarctica.";
RL   J. Bacteriol. 194:6689-6690(2012).
CC   -!- COFACTOR:
CC       Name=pyridoxal 5'-phosphate; Xref=ChEBI:CHEBI:597326;
CC         Evidence={ECO:0000256|ARBA:ARBA00001933,
CC         ECO:0000256|PIRSR:PIRSR600821-50};
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DR   EMBL; CP003063; AFS69626.1; -; Genomic_DNA.
DR   AlphaFoldDB; K0AAA4; -.
DR   STRING; 1087448.Eab7_0468; -.
DR   KEGG; ean:Eab7_0468; -.
DR   PATRIC; fig|1087448.3.peg.473; -.
DR   eggNOG; COG0787; Bacteria.
DR   HOGENOM; CLU_028393_2_1_9; -.
DR   Proteomes; UP000006274; Chromosome.
DR   GO; GO:0008784; F:alanine racemase activity; IEA:InterPro.
DR   GO; GO:0006522; P:alanine metabolic process; IEA:InterPro.
DR   CDD; cd00430; PLPDE_III_AR; 1.
DR   Gene3D; 3.20.20.10; Alanine racemase; 1.
DR   InterPro; IPR000821; Ala_racemase.
DR   InterPro; IPR009006; Ala_racemase/Decarboxylase_C.
DR   InterPro; IPR011079; Ala_racemase_C.
DR   InterPro; IPR001608; Ala_racemase_N.
DR   InterPro; IPR029066; PLP-binding_barrel.
DR   NCBIfam; TIGR00492; alr; 1.
DR   PANTHER; PTHR30511; ALANINE RACEMASE; 1.
DR   PANTHER; PTHR30511:SF0; ALANINE RACEMASE, CATABOLIC-RELATED; 1.
DR   Pfam; PF00842; Ala_racemase_C; 1.
DR   Pfam; PF01168; Ala_racemase_N; 1.
DR   PRINTS; PR00992; ALARACEMASE.
DR   SMART; SM01005; Ala_racemase_C; 1.
DR   SUPFAM; SSF50621; Alanine racemase C-terminal domain-like; 1.
DR   SUPFAM; SSF51419; PLP-binding barrel; 1.
PE   4: Predicted;
KW   Isomerase {ECO:0000256|ARBA:ARBA00023235};
KW   Pyridoxal phosphate {ECO:0000256|ARBA:ARBA00022898,
KW   ECO:0000256|PIRSR:PIRSR600821-50}.
FT   DOMAIN          200..321
FT                   /note="Alanine racemase C-terminal"
FT                   /evidence="ECO:0000259|SMART:SM01005"
FT   BINDING         95
FT                   /ligand="substrate"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR600821-52"
FT   BINDING         268
FT                   /ligand="substrate"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR600821-52"
FT   MOD_RES         3
FT                   /note="N6-(pyridoxal phosphate)lysine"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR600821-50"
SQ   SEQUENCE   321 AA;  35799 MW;  34AE777F6ABF7544 CRC64;
     MVKNNAYNLG MIEMVATLME AGVRHFAVAE VYEAIEIKTN FPDSYVLAMN PASHFKEVRL
     HGVALGIPSL DWLTRHQADL SGIELHLKVN VGMNRFGVSS LQEALSVLET VCEQDLALTG
     LYTHFPLADE PGADHDGQVE RFLEITDVLR TKQSFPYIHA ENSATIVKHD PRLAFCNYVR
     PGIFLFGYSP IEKMDWLIPS LRMTTEVVEI RQVEAGEHVG YGTSYTAPET IRVAVLPVGY
     GDGVVRGRSS LPVIINGKRY PIISKLFMSH TFIAIDSTVQ IGDKVVLYGD GIEIDDITRT
     GTANNSEQMC ARSWRLTHRY L
//