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Protein
Submitted name:

Apolipoprotein E

Gene

APOE

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Biological processLipid transportSAAS annotation, Transport

Names & Taxonomyi

Protein namesi
Submitted name:
Apolipoprotein EImported
Gene namesi
Name:APOEImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

SecretedSAAS annotation

PTM / Processingi

Keywords - PTMi

LipoproteinImported

Proteomic databases

PeptideAtlasiJ9ZVQ3

Structurei

3D structure databases

SMRiJ9ZVQ3
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili77 – 97Sequence analysisAdd BLAST21
Coiled coili165 – 199Sequence analysisAdd BLAST35

Sequence similaritiesi

Belongs to the apolipoprotein A1/A4/E family.SAAS annotation

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

eggNOGiENOG410IVK0 Eukaryota
ENOG4111MYC LUCA

Family and domain databases

InterProiView protein in InterPro
IPR000074 ApoA_E
PfamiView protein in Pfam
PF01442 Apolipoprotein, 1 hit

Sequencei

Sequence statusi: Fragment.

J9ZVQ3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
ALMDETMKEL KAYKSELEEQ LTPVAEETRA RLSKELQAAQ ARLGADMEDV
60 70 80 90 100
CGRLVQYRGE VQAMLGQSTE ELRVRLASHL RKLRKRLLRD ADDLQKRLAV
110 120 130 140 150
YQAGAREGAE RGLSAIRERL GPLVEQGRVR AATVGSLAGQ PLQERAQAWG
160 170 180 190 200
ERLRARMEEM GSRTRDRLDE VKEQVAEVRA KLEEQAQQIR LQAEAFQARL
210 220 230
KSWFEPLVED MQRQWAGLVE KVQAAVGTSA APVPSDNH
Length:238
Mass (Da):26,852
Last modified:November 28, 2012 - v1
Checksum:iA665283C8BAAE034
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei1Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
JX467472 Genomic DNA Translation: AFS60672.1
UniGeneiHs.654439

Similar proteinsi

Entry informationi

Entry nameiJ9ZVQ3_HUMAN
AccessioniPrimary (citable) accession number: J9ZVQ3
Entry historyiIntegrated into UniProtKB/TrEMBL: November 28, 2012
Last sequence update: November 28, 2012
Last modified: January 31, 2018
This is version 36 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

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