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J9ZF19

- J9ZF19_LEPFM

UniProt

J9ZF19 - J9ZF19_LEPFM

Protein

Alanine racemase

Gene

LFML04_2348

Organism
Leptospirillum ferriphilum (strain ML-04)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 13 (01 Oct 2014)
      Sequence version 1 (28 Nov 2012)
      Previous versions | rss
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    Functioni

    Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.UniRule annotation

    Catalytic activityi

    L-alanine = D-alanine.UniRule annotationSAAS annotation

    Cofactori

    Pyridoxal phosphate.UniRule annotationSAAS annotation

    Pathwayi

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei52 – 521Proton acceptor; specific for D-alanineUniRule annotation
    Binding sitei148 – 1481SubstrateUniRule annotation
    Active sitei288 – 2881Proton acceptor; specific for L-alanineUniRule annotation
    Binding sitei336 – 3361Substrate; via amide nitrogenUniRule annotation

    GO - Molecular functioni

    1. alanine racemase activity Source: UniProtKB-HAMAP
    2. pyridoxal phosphate binding Source: UniProtKB-HAMAP

    GO - Biological processi

    1. D-alanine biosynthetic process Source: UniProtKB-UniPathway

    Keywords - Molecular functioni

    IsomeraseUniRule annotationSAAS annotation

    Keywords - Ligandi

    Pyridoxal phosphateUniRule annotationSAAS annotation

    Enzyme and pathway databases

    UniPathwayiUPA00042; UER00497.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Alanine racemaseUniRule annotation (EC:5.1.1.1UniRule annotation)
    Gene namesi
    Ordered Locus Names:LFML04_2348Imported
    OrganismiLeptospirillum ferriphilum (strain ML-04)Imported
    Taxonomic identifieri1048260 [NCBI]
    Taxonomic lineageiBacteriaNitrospiraeNitrospiralesNitrospiraceaeLeptospirillum
    ProteomesiUP000006177: Chromosome

    PTM / Processingi

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Modified residuei52 – 521N6-(pyridoxal phosphate)lysineUniRule annotation

    Structurei

    3D structure databases

    ProteinModelPortaliJ9ZF19.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the alanine racemase family.UniRule annotation

    Phylogenomic databases

    KOiK01775.

    Family and domain databases

    Gene3Di2.40.37.10. 1 hit.
    3.20.20.10. 1 hit.
    HAMAPiMF_01201. Ala_racemase.
    InterProiIPR000821. Ala_racemase.
    IPR009006. Ala_racemase/Decarboxylase_C.
    IPR011079. Ala_racemase_C.
    IPR001608. Ala_racemase_N.
    IPR020622. Ala_racemase_pyridoxalP-BS.
    IPR029066. PLP-binding_barrel.
    [Graphical view]
    PfamiPF00842. Ala_racemase_C. 1 hit.
    PF01168. Ala_racemase_N. 1 hit.
    [Graphical view]
    PRINTSiPR00992. ALARACEMASE.
    SMARTiSM01005. Ala_racemase_C. 1 hit.
    [Graphical view]
    SUPFAMiSSF50621. SSF50621. 1 hit.
    SSF51419. SSF51419. 1 hit.
    TIGRFAMsiTIGR00492. alr. 1 hit.
    PROSITEiPS00395. ALANINE_RACEMASE. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    J9ZF19-1 [UniParc]FASTAAdd to Basket

    « Hide

    MESESSLIEI PGYAGRDLSR SRLIVDLDAL SNNLEWIRSR LPSSIEILPV    50
    VKADAYGHGM LPVAKNFVEK GVPALGVMGL EEGVRLRKAE ISAKVIVMGG 100
    ILPSELEDCI AFGLTPVIHN CELLEAALDL SRKMEVHIHL KFDVGMGRLG 150
    FLPEDISWVC DKIGMESSLR IEGVMSHFPE GEKISETSRQ IGIFGCMVDE 200
    LWDRGALCDR PFVIHLANSA AFLSGQYSVT DKKNRAWEKY ARYWIRPGIL 250
    LYGIPVDPLP LPGLKPAMEI QARLISLKTL SEGSRISYGG TLSLSRKTRV 300
    GVLGMGYADG LPRELSNWGW ASRMGQKFPF LGRVCMDMVM VDVTDAESPV 350
    CLGDWMTVLG NGEDSSMSAW DIAGRIRSIP YEIVCRMGNR SPRFYSRKAS 400
    SSENFG 406
    Length:406
    Mass (Da):44,851
    Last modified:November 28, 2012 - v1
    Checksum:iACABD93C1AC26550
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP002919 Genomic DNA. Translation: AFS54538.1.
    RefSeqiYP_006767498.1. NC_018649.1.

    Genome annotation databases

    EnsemblBacteriaiAFS54538; AFS54538; LFML04_2348.
    GeneIDi13688421.
    KEGGilfi:LFML04_2348.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP002919 Genomic DNA. Translation: AFS54538.1 .
    RefSeqi YP_006767498.1. NC_018649.1.

    3D structure databases

    ProteinModelPortali J9ZF19.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AFS54538 ; AFS54538 ; LFML04_2348 .
    GeneIDi 13688421.
    KEGGi lfi:LFML04_2348.

    Phylogenomic databases

    KOi K01775.

    Enzyme and pathway databases

    UniPathwayi UPA00042 ; UER00497 .

    Family and domain databases

    Gene3Di 2.40.37.10. 1 hit.
    3.20.20.10. 1 hit.
    HAMAPi MF_01201. Ala_racemase.
    InterProi IPR000821. Ala_racemase.
    IPR009006. Ala_racemase/Decarboxylase_C.
    IPR011079. Ala_racemase_C.
    IPR001608. Ala_racemase_N.
    IPR020622. Ala_racemase_pyridoxalP-BS.
    IPR029066. PLP-binding_barrel.
    [Graphical view ]
    Pfami PF00842. Ala_racemase_C. 1 hit.
    PF01168. Ala_racemase_N. 1 hit.
    [Graphical view ]
    PRINTSi PR00992. ALARACEMASE.
    SMARTi SM01005. Ala_racemase_C. 1 hit.
    [Graphical view ]
    SUPFAMi SSF50621. SSF50621. 1 hit.
    SSF51419. SSF51419. 1 hit.
    TIGRFAMsi TIGR00492. alr. 1 hit.
    PROSITEi PS00395. ALANINE_RACEMASE. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Complete genome of Leptospirillum ferriphilum ML-04 provides insight into its physiology and environmental adaptation."
      Mi S., Song J., Lin J., Che Y., Zheng H., Lin J.
      J. Microbiol. 49:890-901(2011) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ML-04Imported.

    Entry informationi

    Entry nameiJ9ZF19_LEPFM
    AccessioniPrimary (citable) accession number: J9ZF19
    Entry historyi
    Integrated into UniProtKB/TrEMBL: November 28, 2012
    Last sequence update: November 28, 2012
    Last modified: October 1, 2014
    This is version 13 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3