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J9Z2K9

- J9Z2K9_9PROT

UniProt

J9Z2K9 - J9Z2K9_9PROT

Protein

Alanine racemase

Gene

HIMB59_00013440

Organism
alpha proteobacterium HIMB59
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 15 (01 Oct 2014)
      Sequence version 1 (28 Nov 2012)
      Previous versions | rss
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    • Comment

    Functioni

    Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.UniRule annotation

    Catalytic activityi

    L-alanine = D-alanine.UniRule annotationSAAS annotation

    Cofactori

    Pyridoxal phosphate.UniRule annotationSAAS annotation

    Pathwayi

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei37 – 371Proton acceptor; specific for D-alanineUniRule annotation
    Binding sitei133 – 1331SubstrateUniRule annotation
    Active sitei251 – 2511Proton acceptor; specific for L-alanineUniRule annotation
    Binding sitei299 – 2991Substrate; via amide nitrogenUniRule annotation

    GO - Molecular functioni

    1. alanine racemase activity Source: UniProtKB-HAMAP
    2. pyridoxal phosphate binding Source: UniProtKB-HAMAP

    GO - Biological processi

    1. D-alanine biosynthetic process Source: UniProtKB-UniPathway

    Keywords - Molecular functioni

    IsomeraseUniRule annotationSAAS annotation

    Keywords - Ligandi

    Pyridoxal phosphateUniRule annotationSAAS annotation

    Enzyme and pathway databases

    UniPathwayiUPA00042; UER00497.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Alanine racemaseUniRule annotation (EC:5.1.1.1UniRule annotation)
    Gene namesi
    ORF Names:HIMB59_00013440Imported
    Organismialpha proteobacterium HIMB59Imported
    Taxonomic identifieri744985 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaSAR11 cluster
    ProteomesiUP000006097: Chromosome

    PTM / Processingi

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Modified residuei37 – 371N6-(pyridoxal phosphate)lysineUniRule annotation

    Structurei

    3D structure databases

    ProteinModelPortaliJ9Z2K9.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the alanine racemase family.UniRule annotation

    Phylogenomic databases

    KOiK01775.

    Family and domain databases

    Gene3Di2.40.37.10. 1 hit.
    3.20.20.10. 1 hit.
    HAMAPiMF_01201. Ala_racemase.
    InterProiIPR000821. Ala_racemase.
    IPR009006. Ala_racemase/Decarboxylase_C.
    IPR011079. Ala_racemase_C.
    IPR001608. Ala_racemase_N.
    IPR020622. Ala_racemase_pyridoxalP-BS.
    IPR029066. PLP-binding_barrel.
    [Graphical view]
    PfamiPF00842. Ala_racemase_C. 1 hit.
    PF01168. Ala_racemase_N. 1 hit.
    [Graphical view]
    PRINTSiPR00992. ALARACEMASE.
    SMARTiSM01005. Ala_racemase_C. 1 hit.
    [Graphical view]
    SUPFAMiSSF50621. SSF50621. 1 hit.
    SSF51419. SSF51419. 1 hit.
    TIGRFAMsiTIGR00492. alr. 1 hit.
    PROSITEiPS00395. ALANINE_RACEMASE. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    J9Z2K9-1 [UniParc]FASTAAdd to Basket

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    MKKLDNKQIY INRQYLINNY DILKKKAENS KIMSVIKGDA YGHGIQQCSD    50
    VLEKNGCNHF YVARLDDAIS LRKKHQKKIN IYLLSGTISK EICGYIKRYE 100
    ITPIINNLKQ LEIFNRFIPH TKFVLHFDTG MNRLGFKIEE INQIKELSIL 150
    KNVQFLMTHL SSADEQNIKE CRFQLNQLKR INKLFNKPLS IANSSGIFLG 200
    KSFHLNYVRP GKSLYGINPF LKKSFGLKGV MSIYAPILQI TSIKKGQTVG 250
    YSKTFKAKKN IKVATVDFGY SDGYLRSGSN RTKVFIDGII CNVLGRVSMD 300
    LITIDVSNVD ENSLYLGKPV EILGENQSCE DLALELGTNE HEVLISLGKN 350
    SKKVYI 356
    Length:356
    Mass (Da):40,519
    Last modified:November 28, 2012 - v1
    Checksum:iDF4B7BF28D2E72D5
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP003801 Genomic DNA. Translation: AFS49520.1.
    RefSeqiWP_014955351.1. NC_018644.1.
    YP_006758697.1. NC_018644.1.

    Genome annotation databases

    EnsemblBacteriaiAFS49520; AFS49520; HIMB59_00013440.
    GeneIDi13676120.
    KEGGiapc:HIMB59_00013440.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP003801 Genomic DNA. Translation: AFS49520.1 .
    RefSeqi WP_014955351.1. NC_018644.1.
    YP_006758697.1. NC_018644.1.

    3D structure databases

    ProteinModelPortali J9Z2K9.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AFS49520 ; AFS49520 ; HIMB59_00013440 .
    GeneIDi 13676120.
    KEGGi apc:HIMB59_00013440.

    Phylogenomic databases

    KOi K01775.

    Enzyme and pathway databases

    UniPathwayi UPA00042 ; UER00497 .

    Family and domain databases

    Gene3Di 2.40.37.10. 1 hit.
    3.20.20.10. 1 hit.
    HAMAPi MF_01201. Ala_racemase.
    InterProi IPR000821. Ala_racemase.
    IPR009006. Ala_racemase/Decarboxylase_C.
    IPR011079. Ala_racemase_C.
    IPR001608. Ala_racemase_N.
    IPR020622. Ala_racemase_pyridoxalP-BS.
    IPR029066. PLP-binding_barrel.
    [Graphical view ]
    Pfami PF00842. Ala_racemase_C. 1 hit.
    PF01168. Ala_racemase_N. 1 hit.
    [Graphical view ]
    PRINTSi PR00992. ALARACEMASE.
    SMARTi SM01005. Ala_racemase_C. 1 hit.
    [Graphical view ]
    SUPFAMi SSF50621. SSF50621. 1 hit.
    SSF51419. SSF51419. 1 hit.
    TIGRFAMsi TIGR00492. alr. 1 hit.
    PROSITEi PS00395. ALANINE_RACEMASE. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE.
      Strain: HIMB59Imported.

    Entry informationi

    Entry nameiJ9Z2K9_9PROT
    AccessioniPrimary (citable) accession number: J9Z2K9
    Entry historyi
    Integrated into UniProtKB/TrEMBL: November 28, 2012
    Last sequence update: November 28, 2012
    Last modified: October 1, 2014
    This is version 15 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3