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J9Z2K9

- J9Z2K9_9PROT

UniProt

J9Z2K9 - J9Z2K9_9PROT

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Protein

Alanine racemase

Gene
HIMB59_00013440
Organism
alpha proteobacterium HIMB59
Status
Unreviewed - Annotation score: 2 out of 5 - Experimental evidence at protein leveli

Functioni

Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids By similarity.UniRule annotation

Catalytic activityi

L-alanine = D-alanine.UniRule annotationSAAS annotations

Cofactori

Pyridoxal phosphate By similarity.UniRule annotationSAAS annotations

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei37 – 371Proton acceptor; specific for D-alanine By similarityUniRule annotation
Binding sitei133 – 1331Substrate By similarityUniRule annotation
Active sitei251 – 2511Proton acceptor; specific for L-alanine By similarityUniRule annotation
Binding sitei299 – 2991Substrate; via amide nitrogen By similarityUniRule annotation

GO - Molecular functioni

  1. alanine racemase activity Source: UniProtKB-HAMAP
  2. pyridoxal phosphate binding Source: UniProtKB-HAMAP

GO - Biological processi

  1. D-alanine biosynthetic process Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

IsomeraseUniRule annotationSAAS annotations

Keywords - Ligandi

Pyridoxal phosphateUniRule annotationSAAS annotations

Enzyme and pathway databases

UniPathwayiUPA00042; UER00497.

Names & Taxonomyi

Protein namesi
Recommended name:
Alanine racemaseUniRule annotation (EC:5.1.1.1UniRule annotation)
Gene namesi
ORF Names:HIMB59_00013440Imported
Organismialpha proteobacterium HIMB59Imported
Taxonomic identifieri744985 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaSAR11 cluster
ProteomesiUP000006097: Chromosome

PTM / Processingi

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei37 – 371N6-(pyridoxal phosphate)lysine By similarityUniRule annotation

Structurei

3D structure databases

ProteinModelPortaliJ9Z2K9.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

KOiK01775.

Family and domain databases

Gene3Di2.40.37.10. 1 hit.
3.20.20.10. 1 hit.
HAMAPiMF_01201. Ala_racemase.
InterProiIPR000821. Ala_racemase.
IPR009006. Ala_racemase/Decarboxylase_C.
IPR011079. Ala_racemase_C.
IPR001608. Ala_racemase_N.
IPR020622. Ala_racemase_pyridoxalP-BS.
IPR029066. PLP-binding_barrel.
[Graphical view]
PfamiPF00842. Ala_racemase_C. 1 hit.
PF01168. Ala_racemase_N. 1 hit.
[Graphical view]
PRINTSiPR00992. ALARACEMASE.
SMARTiSM01005. Ala_racemase_C. 1 hit.
[Graphical view]
SUPFAMiSSF50621. SSF50621. 1 hit.
SSF51419. SSF51419. 1 hit.
TIGRFAMsiTIGR00492. alr. 1 hit.
PROSITEiPS00395. ALANINE_RACEMASE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

J9Z2K9-1 [UniParc]FASTAAdd to Basket

« Hide

MKKLDNKQIY INRQYLINNY DILKKKAENS KIMSVIKGDA YGHGIQQCSD    50
VLEKNGCNHF YVARLDDAIS LRKKHQKKIN IYLLSGTISK EICGYIKRYE 100
ITPIINNLKQ LEIFNRFIPH TKFVLHFDTG MNRLGFKIEE INQIKELSIL 150
KNVQFLMTHL SSADEQNIKE CRFQLNQLKR INKLFNKPLS IANSSGIFLG 200
KSFHLNYVRP GKSLYGINPF LKKSFGLKGV MSIYAPILQI TSIKKGQTVG 250
YSKTFKAKKN IKVATVDFGY SDGYLRSGSN RTKVFIDGII CNVLGRVSMD 300
LITIDVSNVD ENSLYLGKPV EILGENQSCE DLALELGTNE HEVLISLGKN 350
SKKVYI 356
Length:356
Mass (Da):40,519
Last modified:November 28, 2012 - v1
Checksum:iDF4B7BF28D2E72D5
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP003801 Genomic DNA. Translation: AFS49520.1.
RefSeqiWP_014955351.1. NC_018644.1.
YP_006758697.1. NC_018644.1.

Genome annotation databases

EnsemblBacteriaiAFS49520; AFS49520; HIMB59_00013440.
GeneIDi13676120.
KEGGiapc:HIMB59_00013440.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP003801 Genomic DNA. Translation: AFS49520.1 .
RefSeqi WP_014955351.1. NC_018644.1.
YP_006758697.1. NC_018644.1.

3D structure databases

ProteinModelPortali J9Z2K9.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AFS49520 ; AFS49520 ; HIMB59_00013440 .
GeneIDi 13676120.
KEGGi apc:HIMB59_00013440.

Phylogenomic databases

KOi K01775.

Enzyme and pathway databases

UniPathwayi UPA00042 ; UER00497 .

Family and domain databases

Gene3Di 2.40.37.10. 1 hit.
3.20.20.10. 1 hit.
HAMAPi MF_01201. Ala_racemase.
InterProi IPR000821. Ala_racemase.
IPR009006. Ala_racemase/Decarboxylase_C.
IPR011079. Ala_racemase_C.
IPR001608. Ala_racemase_N.
IPR020622. Ala_racemase_pyridoxalP-BS.
IPR029066. PLP-binding_barrel.
[Graphical view ]
Pfami PF00842. Ala_racemase_C. 1 hit.
PF01168. Ala_racemase_N. 1 hit.
[Graphical view ]
PRINTSi PR00992. ALARACEMASE.
SMARTi SM01005. Ala_racemase_C. 1 hit.
[Graphical view ]
SUPFAMi SSF50621. SSF50621. 1 hit.
SSF51419. SSF51419. 1 hit.
TIGRFAMsi TIGR00492. alr. 1 hit.
PROSITEi PS00395. ALANINE_RACEMASE. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: HIMB59Imported.

Entry informationi

Entry nameiJ9Z2K9_9PROT
AccessioniPrimary (citable) accession number: J9Z2K9
Entry historyi
Integrated into UniProtKB/TrEMBL: November 28, 2012
Last sequence update: November 28, 2012
Last modified: September 3, 2014
This is version 14 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome

External Data

Dasty 3