ID   J9Z200_HUMAN            Unreviewed;        89 AA.
AC   J9Z200;
DT   28-NOV-2012, integrated into UniProtKB/TrEMBL.
DT   28-NOV-2012, sequence version 1.
DT   27-MAR-2024, entry version 20.
DE   SubName: Full=MHC class II antigen {ECO:0000313|EMBL:AFS49949.1};
DE   Flags: Fragment;
GN   Name=HLA-DRB1 {ECO:0000313|EMBL:AFS49949.1};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|EMBL:AFS49949.1};
RN   [1] {ECO:0000313|EMBL:AFS49949.1}
RP   NUCLEOTIDE SEQUENCE.
RX   PubMed=23126463; DOI=10.1111/tan.12021;
RA   Kim K.M., Sung H.Y., Kang M.S., Huh J.Y.;
RT   "Identification of two novel HLA alleles: HLA-DRB1*12:03:03 and HLA-
RT   DRB1*13:143.";
RL   Tissue Antigens 81:58-59(2013).
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DR   EMBL; JX315459; AFS49949.1; -; Genomic_DNA.
DR   AlphaFoldDB; J9Z200; -.
DR   PeptideAtlas; J9Z200; -.
DR   ChiTaRS; HLA-DRB1; human.
DR   GO; GO:0042613; C:MHC class II protein complex; IEA:InterPro.
DR   GO; GO:0019882; P:antigen processing and presentation; IEA:InterPro.
DR   GO; GO:0006955; P:immune response; IEA:InterPro.
DR   InterPro; IPR011162; MHC_I/II-like_Ag-recog.
DR   InterPro; IPR014745; MHC_II_a/b_N.
DR   InterPro; IPR000353; MHC_II_b_N.
DR   PANTHER; PTHR19944:SF99; HLA CLASS II HISTOCOMPATIBILITY ANTIGEN, DR BETA 3 CHAIN; 1.
DR   PANTHER; PTHR19944; MHC CLASS II-RELATED; 1.
DR   Pfam; PF00969; MHC_II_beta; 1.
DR   SMART; SM00921; MHC_II_beta; 1.
DR   SUPFAM; SSF54452; MHC antigen-recognition domain; 1.
PE   4: Predicted;
KW   Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW   Signal {ECO:0000256|ARBA:ARBA00022729}.
FT   DOMAIN          8..82
FT                   /note="MHC class II beta chain N-terminal"
FT                   /evidence="ECO:0000259|SMART:SM00921"
FT   NON_TER         1
FT                   /evidence="ECO:0000313|EMBL:AFS49949.1"
FT   NON_TER         89
FT                   /evidence="ECO:0000313|EMBL:AFS49949.1"
SQ   SEQUENCE   89 AA;  10758 MW;  E4C1292C39B3C873 CRC64;
     RFLEYSTSEC HFFNGTERVR FLDRYFHNQE ENVRFDSDVG EFRAVTELGR PDAEYWNSQK
     DILEDERAAV DTYCRHNYGF GESFTVQRR
//