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Protein

Phosphoenolpyruvate carboxylase

Gene

ppc

Organism
alpha proteobacterium HIMB5
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.UniRule annotationSAAS annotation

Catalytic activityi

Phosphate + oxaloacetate = H2O + phosphoenolpyruvate + HCO3-.UniRule annotationSAAS annotation

Cofactori

Mg2+UniRule annotationSAAS annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei154 – 1541UniRule annotation
Active sitei559 – 5591UniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

LyaseUniRule annotationSAAS annotation

Keywords - Biological processi

Carbon dioxide fixationUniRule annotationSAAS annotation

Keywords - Ligandi

MagnesiumUniRule annotationSAAS annotation, PyruvateImported

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoenolpyruvate carboxylaseUniRule annotationSAAS annotation (EC:4.1.1.31UniRule annotationSAAS annotation)
Short name:
PEPCUniRule annotation
Short name:
PEPCaseUniRule annotation
Gene namesi
Name:ppcUniRule annotation
ORF Names:HIMB5_00003710Imported
Organismialpha proteobacterium HIMB5Imported
Taxonomic identifieri859653 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaSAR11 cluster
ProteomesiUP000006098 Componenti: Chromosome

Interactioni

Subunit structurei

Homotetramer.UniRule annotation

Family & Domainsi

Sequence similaritiesi

Belongs to the PEPCase type 1 family.UniRule annotation

Phylogenomic databases

KOiK01595.

Family and domain databases

HAMAPiMF_00595. PEPcase_type1.
InterProiIPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view]
PfamiPF00311. PEPcase. 1 hit.
[Graphical view]
PRINTSiPR00150. PEPCARBXLASE.
SUPFAMiSSF51621. SSF51621. 1 hit.
PROSITEiPS00781. PEPCASE_1. 1 hit.
PS00393. PEPCASE_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

J9YVY3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKKRDLYYDR IPTKFLREDI RLLGKILGDV LKEQEGGKFF KLVEDIRLLS
60 70 80 90 100
KPSLNNYGSK NPHDRLSNKI KNLNSETIFK LTRAFNHFCN LMNLAEAHDT
110 120 130 140 150
SHTLNEIEQN KNKKTKSLFI EEIFKNFFKN KLIPNKKIYD LAQNLKIGVV
160 170 180 190 200
LTAHPTEVKR RTLIQKYANL IELLEQRYLY KNFQKKINEI DKALYSEITI
210 220 230 240 250
IWKTDDIKRS KPSPLDEARW GLAIIEDSLW DTIPRVYKRL NKIFKKNYGK
260 270 280 290 300
DLPRSFNPIE FGSWMGGDRD GNPNVTSKVT EKVILFSRWQ AAKLYERELT
310 320 330 340 350
KLIQDLSMQN CSSKIKKISK NSFEPYRVYL RPIRDKIRST YINIEEHLNK
360 370 380 390 400
NKKLNNDLLF KDKYELINVL RDVRKSLNEN NDKRIGNSVL LDLLRRARCF
410 420 430 440 450
GINLAKLDIR QESSRHSLLV SEILRNNLRI KFENFDENKK VQLLSKLITD
460 470 480 490 500
KKGLKNLKLK NKLNKEVWNT FEVISKQPIE CLGAYVISMT SSSSDILNVY
510 520 530 540 550
YLQKLAKISQ PLRVVPLLET LDDLKNGKKI MEKLFSLSWY RKLIKNKQEV
560 570 580 590 600
MIGYSDSSKD AGKLSSSWNQ YKVEEELRNI AKKYKISLTF FHGRGGSPGR
610 620 630 640 650
GGGPIQSTLK SQPSNTVNGK IRITDQGEVI QQKYGYKPLA EYNLCSYIGS
660 670 680 690 700
VMEATLNPPP KSKPQWRSLI ERMTELSTAS YRRSINANEE FIRYFKTVTP
710 720 730 740 750
HKALGKLSIG SRPTKRKNVD NIQSLRAIPW VFAWTQIRLL LPAWLGTSEA
760 770 780 790 800
LRYAGIKKFK NVLNDMQINW PFFSSTMDIL DMVISKVDPE ISIIYENNLA
810 820 830 840 850
DDKLRRVGKK LRFQFDQLVK LHKKITPKEI LNERKKFRKS LYVRNNYTEV
860 870 880 890
LNVLQAKIMG KLNSKKLSNL DRKFLEDALM TSIAGISAAI KNTG
Length:894
Mass (Da):104,022
Last modified:November 28, 2012 - v1
Checksum:i9B62E6CDD48A01AE
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP003809 Genomic DNA. Translation: AFS47140.1.
RefSeqiWP_014952972.1. NC_018643.1.
YP_006756317.1. NC_018643.1.

Genome annotation databases

EnsemblBacteriaiAFS47140; AFS47140; HIMB5_00003710.
KEGGiapm:HIMB5_00003710.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP003809 Genomic DNA. Translation: AFS47140.1.
RefSeqiWP_014952972.1. NC_018643.1.
YP_006756317.1. NC_018643.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAFS47140; AFS47140; HIMB5_00003710.
KEGGiapm:HIMB5_00003710.

Phylogenomic databases

KOiK01595.

Family and domain databases

HAMAPiMF_00595. PEPcase_type1.
InterProiIPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view]
PfamiPF00311. PEPcase. 1 hit.
[Graphical view]
PRINTSiPR00150. PEPCARBXLASE.
SUPFAMiSSF51621. SSF51621. 1 hit.
PROSITEiPS00781. PEPCASE_1. 1 hit.
PS00393. PEPCASE_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: HIMB5Imported.

Entry informationi

Entry nameiJ9YVY3_9PROT
AccessioniPrimary (citable) accession number: J9YVY3
Entry historyi
Integrated into UniProtKB/TrEMBL: November 28, 2012
Last sequence update: November 28, 2012
Last modified: June 24, 2015
This is version 20 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.