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Protein

Phosphoenolpyruvate carboxylase

Gene

ppcA

Organism
Leuconostoc gelidum (strain JB7)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalyzes the irreversible beta-carboxylation of phosphoenolpyruvate (PEP) to form oxaloacetate (OAA), a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.UniRule annotation

Catalytic activityi

Phosphate + oxaloacetate = H2O + phosphoenolpyruvate + HCO3-.UniRule annotation

Cofactori

Mg2+UniRule annotation

GO - Molecular functioni

  1. magnesium ion binding Source: UniProtKB-HAMAP
  2. phosphoenolpyruvate carboxylase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. carbon fixation Source: UniProtKB-HAMAP
  2. oxaloacetate metabolic process Source: UniProtKB-HAMAP
  3. tricarboxylic acid cycle Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

LyaseUniRule annotationImported

Keywords - Biological processi

Carbon dioxide fixationUniRule annotation

Keywords - Ligandi

MagnesiumUniRule annotation, PyruvateImported

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoenolpyruvate carboxylaseUniRule annotation (EC:4.1.1.31UniRule annotation)
Short name:
PEPCUniRule annotation
Short name:
PEPCaseUniRule annotation
Gene namesi
Name:ppcAUniRule annotation
Ordered Locus Names:C269_02420Imported
OrganismiLeuconostoc gelidum (strain JB7)Imported
Taxonomic identifieri1229756 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliLactobacillalesLeuconostocaceaeLeuconostoc
ProteomesiUP000006279 Componenti: Chromosome

Interactioni

Subunit structurei

Homotetramer.UniRule annotation

Family & Domainsi

Sequence similaritiesi

Belongs to the PEPCase type 2 family.UniRule annotation

Phylogenomic databases

KOiK01595.

Family and domain databases

HAMAPiMF_01904. PEPcase_type2.
InterProiIPR007566. PEP_COase_arc-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view]
PfamiPF14010. PEPcase_2. 1 hit.
[Graphical view]
PIRSFiPIRSF006677. UCP006677. 1 hit.
SUPFAMiSSF51621. SSF51621. 1 hit.
TIGRFAMsiTIGR02751. PEPCase_arch. 1 hit.

Sequencei

Sequence statusi: Complete.

J9YEZ4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTQRKFPTIM GTQHPDNANA PFWDASQQPF ISAYREMNEA FENFSELNVD
60 70 80 90 100
EYMWDWEGKH ADAAVIDRLF STEYDYFKTN QIGRDKFLTF RFPNIWEEKG
110 120 130 140 150
YSLMQAMTAI LSSEDFAHDL GFDQRPLFEA ILPMAQRADQ LLEMQILFEK
160 170 180 190 200
LANFKSVEFT KTDKNTPYIE MIPLFEDFNT QLHAPEILKE YLKLHEEHFG
210 220 230 240 250
FRPKYLRVFL AGSDSALTAG FMSSITGNKL AIARLHEFAK EENIDIYPIS
260 270 280 290 300
GTGSAIFRGG LSPHRIDRYV TEFPGVRTAT VQSAFRYDFP LADVQQAITE
310 320 330 340 350
LKEKLPNAEP LKISANDQKI LAEVAEESAR FYADTLDQLI PDMQPIFKAF
360 370 380 390 400
PKRRDRRQHV GVLGYSRSVD GIELPRAINF TGSFYSIGIP PEFIGFGRAL
410 420 430 440 450
ANLNADHLSV FVRNYPSMKK DFRELAGYIN LDALEILKTQ SPAWSEVEQD
460 470 480 490 500
IMTLKAIFNL EIGPHNREQQ QHAEIALQVV QIKDGAPVAT TALINRMAQL

RHFLG
Length:505
Mass (Da):57,781
Last modified:November 27, 2012 - v1
Checksum:i41F7D2A591888D48
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP003839 Genomic DNA. Translation: AFS39927.1.
RefSeqiWP_010016142.1. NC_018631.1.
YP_006744813.1. NC_018631.1.

Genome annotation databases

EnsemblBacteriaiAFS39927; AFS39927; C269_02420.
KEGGilge:C269_02420.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP003839 Genomic DNA. Translation: AFS39927.1.
RefSeqiWP_010016142.1. NC_018631.1.
YP_006744813.1. NC_018631.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAFS39927; AFS39927; C269_02420.
KEGGilge:C269_02420.

Phylogenomic databases

KOiK01595.

Family and domain databases

HAMAPiMF_01904. PEPcase_type2.
InterProiIPR007566. PEP_COase_arc-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view]
PfamiPF14010. PEPcase_2. 1 hit.
[Graphical view]
PIRSFiPIRSF006677. UCP006677. 1 hit.
SUPFAMiSSF51621. SSF51621. 1 hit.
TIGRFAMsiTIGR02751. PEPCase_arch. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. "Complete genome sequence of Leuconostoc gelidum strain JB7, isolated from Kimchi."
    Jung J.Y., Lee S.H., Jeon C.O.
    J. Bacteriol. 194:6665-6665(2011) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: JB7Imported.

Entry informationi

Entry nameiJ9YEZ4_LEUGJ
AccessioniPrimary (citable) accession number: J9YEZ4
Entry historyi
Integrated into UniProtKB/TrEMBL: November 27, 2012
Last sequence update: November 27, 2012
Last modified: March 31, 2015
This is version 16 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.