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J9WL12

- J9WL12_9MYCO

UniProt

J9WL12 - J9WL12_9MYCO

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Protein

Phosphoenolpyruvate carboxylase

Gene

ppc

Organism
Mycobacterium indicus pranii MTCC 9506
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.UniRule annotation

Catalytic activityi

Phosphate + oxaloacetate = H2O + phosphoenolpyruvate + HCO3-.UniRule annotationSAAS annotation

Cofactori

Magnesium.UniRule annotationSAAS annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei164 – 1641UniRule annotation
Active sitei596 – 5961UniRule annotation

GO - Molecular functioni

  1. magnesium ion binding Source: UniProtKB-HAMAP
  2. phosphoenolpyruvate carboxylase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. carbon fixation Source: UniProtKB-HAMAP
  2. oxaloacetate metabolic process Source: UniProtKB-HAMAP
  3. tricarboxylic acid cycle Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

LyaseUniRule annotationSAAS annotation

Keywords - Biological processi

Carbon dioxide fixationUniRule annotationSAAS annotation

Keywords - Ligandi

MagnesiumUniRule annotationSAAS annotation, PyruvateImported

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoenolpyruvate carboxylaseUniRule annotation (EC:4.1.1.31UniRule annotation)
Short name:
PEPCUniRule annotation
Short name:
PEPCaseUniRule annotation
Gene namesi
Name:ppcUniRule annotation
ORF Names:MIP_04787Imported
OrganismiMycobacterium indicus pranii MTCC 9506Imported
Taxonomic identifieri1232724 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeActinomycetalesCorynebacterineaeMycobacteriaceaeMycobacteriumMycobacterium avium complex (MAC)
ProteomesiUP000007329: Chromosome

Interactioni

Subunit structurei

Homotetramer.UniRule annotation

Family & Domainsi

Sequence similaritiesi

Belongs to the PEPCase type 1 family.UniRule annotation

Phylogenomic databases

KOiK01595.

Family and domain databases

HAMAPiMF_00595. PEPcase_type1.
InterProiIPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view]
PfamiPF00311. PEPcase. 1 hit.
[Graphical view]
PRINTSiPR00150. PEPCARBXLASE.
SUPFAMiSSF51621. SSF51621. 1 hit.
PROSITEiPS00781. PEPCASE_1. 1 hit.
PS00393. PEPCASE_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

J9WL12-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MADASEAPED TLEPIGAVQR TPVGREATEP MRADIRLLGA ILGDTVREQN
60 70 80 90 100
GREVFELVER ARVESFRVRR SEIDRAELAR MFFRIDIHQA IPVIRAFSHF
110 120 130 140 150
ALLANVAEDI HRERRRAVHV AAGEPPPDST LAATYAKLDE AQLDSDTVAD
160 170 180 190 200
ALKGAVVAPV ITAHPTETRR RTVFVTQHRI TELMRLHAEG HAETDDGRNI
210 220 230 240 250
ELELRRQVLT LWQTALIRLS RLQITDEIEV GLRYYAAAFF KVIPQVNAEV
260 270 280 290 300
RDALRARWPD ADLFDEPMLQ PGSWIGGDRD GNPNVTADVV RQATGSAAFT
310 320 330 340 350
ALAHYLAELT ALEQELSMSA RLVSVTPALT ELAGGCAEKA RADEPYRRAA
360 370 380 390 400
RVIRARLSAT SAAILDRTPQ QVLDLGLPPY ETPAELGADL DTIDESLRGH
410 420 430 440 450
GSALLADDRL ALLREGVRVF GFHLCGLDMR QNSDAHEEVI GELLAWAGVH
460 470 480 490 500
PDYRSLPEDE RVELLAAELG TRRPLVADDA QLSDLARGEL DVVRAAAQAI
510 520 530 540 550
KRYGPSAVPN YVISMCRSVS DVLEAAILLK EAGLIDASGA EPYCPVGISP
560 570 580 590 600
LFETIDDLHN GATILHAMLE LPIYRALVAA RGETQEVMLG YSDSNKDGGY
610 620 630 640 650
LASSWAVYRA ELALVEVARK TGIRLRLFHG RGGTVGRGGG PSYEAILAQP
660 670 680 690 700
PGAVNGSLRL TEQGEVIAAK YAEPQAAQRN LESLLAATLE STLLDVEGLG
710 720 730 740 750
DAAEPAYAVL DEVAVLAQRA YAELVHDTPG FVDYFMASTP VSEIGSLNIG
760 770 780 790 800
SRPTSRKPTE SISDLRAIPW VLAWSQSRVM LPGWYGTGSA FEQWIAAGPQ
810 820 830 840 850
SEAERVSILH DLYQRWPFFR SVLSNLAQVL AKSDLGLAAR YAELVDDEEL
860 870 880 890 900
RRRVFGKIVD EHGRTIAMHK LITGQDNLLA DNPALARSVF NRFPYLEPLN
910 920 930
HLQVELLRRY RSGDDDELVQ RGILLTMNGL ASALRNSG
Length:938
Mass (Da):102,754
Last modified:November 28, 2012 - v1
Checksum:i3040797639A5ADF0
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP002275 Genomic DNA. Translation: AFS15237.1.
RefSeqiYP_006730326.1. NC_018612.1.

Genome annotation databases

EnsemblBacteriaiAFS15237; AFS15237; MIP_04787.
GeneIDi13660753.
KEGGimid:MIP_04787.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP002275 Genomic DNA. Translation: AFS15237.1 .
RefSeqi YP_006730326.1. NC_018612.1.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AFS15237 ; AFS15237 ; MIP_04787 .
GeneIDi 13660753.
KEGGi mid:MIP_04787.

Phylogenomic databases

KOi K01595.

Family and domain databases

HAMAPi MF_00595. PEPcase_type1.
InterProi IPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view ]
Pfami PF00311. PEPcase. 1 hit.
[Graphical view ]
PRINTSi PR00150. PEPCARBXLASE.
SUPFAMi SSF51621. SSF51621. 1 hit.
PROSITEi PS00781. PEPCASE_1. 1 hit.
PS00393. PEPCASE_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Molecular analysis of a leprosy immunotherapeutic bacillus provides insights into Mycobacterium evolution."
    Ahmed N., Saini V., Raghuvanshi S., Khurana J.P., Tyagi A.K., Tyagi A.K., Hasnain S.E.
    PLoS ONE 2:E968-E968(2007) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  2. "Massive gene acquisitions in Mycobacterium indicus pranii provide a perspective on mycobacterial evolution."
    Saini V., Raghuvanshi S., Khurana J.P., Ahmed N., Hasnain S.E., Tyagi A.K., Tyagi A.K.
    Nucleic Acids Res. 40:10832-10850(2012) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Entry informationi

Entry nameiJ9WL12_9MYCO
AccessioniPrimary (citable) accession number: J9WL12
Entry historyi
Integrated into UniProtKB/TrEMBL: November 28, 2012
Last sequence update: November 28, 2012
Last modified: October 29, 2014
This is version 13 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

External Data

Dasty 3