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Protein

Thymidine kinase

Gene

tdk

Organism
Lactobacillus buchneri CD034
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + thymidine = ADP + thymidine 5'-phosphate.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei117Proton acceptorUniRule annotation1
Metal bindingi174ZincUniRule annotation1
Metal bindingi177ZincUniRule annotation1
Metal bindingi211ZincUniRule annotation1
Metal bindingi214ZincUniRule annotation1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi40 – 47ATPUniRule annotation8
Nucleotide bindingi116 – 119ATPUniRule annotation4

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionKinaseUniRule annotationImported, Transferase
Biological processDNA synthesisUniRule annotation
LigandATP-bindingUniRule annotation, Metal-bindingUniRule annotation, Nucleotide-binding, ZincUniRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Thymidine kinaseUniRule annotation (EC:2.7.1.21UniRule annotation)
Gene namesi
Name:tdkUniRule annotationImported
ORF Names:LBUCD034_0986Imported
OrganismiLactobacillus buchneri CD034Imported
Taxonomic identifieri1071400 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliLactobacillalesLactobacillaceaeLactobacillus
Proteomesi
  • UP000007332 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

CytoplasmUniRule annotation

Interactioni

Subunit structurei

Homotetramer.UniRule annotation

Family & Domainsi

Sequence similaritiesi

Belongs to the thymidine kinase family.UniRule annotation

Phylogenomic databases

KOiK00857
OrthoDBiPOG091H0659

Family and domain databases

HAMAPiMF_00124 Thymidine_kinase, 1 hit
InterProiView protein in InterPro
IPR027417 P-loop_NTPase
IPR001267 Thymidine_kinase
IPR020633 Thymidine_kinase_CS
PANTHERiPTHR11441 PTHR11441, 1 hit
PfamiView protein in Pfam
PF00265 TK, 1 hit
PIRSFiPIRSF035805 TK_cell, 1 hit
SUPFAMiSSF52540 SSF52540, 1 hit
PROSITEiView protein in PROSITE
PS00603 TK_CELLULAR_TYPE, 1 hit

Sequencei

Sequence statusi: Complete.

J9W4U7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRVLANFLII IDFQNFFCIM EEKLLRKKVD ILAQLFYRYG AMNSGKTIEI
60 70 80 90 100
IKVAHNYEEQ NKSVIIMTSA LDTREKQGMI ESRIGLERKA EPIREDTNVF
110 120 130 140 150
DLVQELNPHA SCILIDEAQF LKKKHVMELA RIVDELNVPV MAFGLKNDFQ
160 170 180 190 200
NNLFEGSKYL LLYADKIEEM KTICWFCGKK AIMNLRFHNG EPVYEGEQIQ
210 220
MGGNESYYPV CRKHYYNPPI K
Length:221
Mass (Da):25,829
Last modified:November 28, 2012 - v1
Checksum:i1872649C9212D512
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP003043 Genomic DNA Translation: AFS00030.1

Genome annotation databases

EnsemblBacteriaiAFS00030; AFS00030; LBUCD034_0986
KEGGilbn:LBUCD034_0986
PATRICifig|1071400.3.peg.940

Similar proteinsi

Entry informationi

Entry nameiJ9W4U7_LACBU
AccessioniPrimary (citable) accession number: J9W4U7
Entry historyiIntegrated into UniProtKB/TrEMBL: November 28, 2012
Last sequence update: November 28, 2012
Last modified: March 28, 2018
This is version 30 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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