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Protein

Xylose isomerase

Gene

xylA

Organism
Lactobacillus buchneri CD034
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

D-xylopyranose = D-xylulose.UniRule annotationSAAS annotation

Cofactori

Mg2+UniRule annotationNote: Binds 2 magnesium ions per subunit.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei100 – 1001UniRule annotation
Active sitei103 – 1031UniRule annotation
Metal bindingi231 – 2311Magnesium 1UniRule annotation
Metal bindingi267 – 2671Magnesium 1UniRule annotation
Metal bindingi267 – 2671Magnesium 2UniRule annotation
Metal bindingi270 – 2701Magnesium 2UniRule annotation
Metal bindingi295 – 2951Magnesium 1UniRule annotation
Metal bindingi306 – 3061Magnesium 2UniRule annotation
Metal bindingi308 – 3081Magnesium 2UniRule annotation
Metal bindingi339 – 3391Magnesium 1UniRule annotation

GO - Molecular functioni

  1. magnesium ion binding Source: UniProtKB-HAMAP
  2. xylose isomerase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. D-xylose metabolic process Source: UniProtKB-HAMAP
  2. pentose-phosphate shunt Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

IsomeraseUniRule annotation

Keywords - Biological processi

Carbohydrate metabolism, Pentose shuntUniRule annotation, Xylose metabolismUniRule annotation

Keywords - Ligandi

MagnesiumUniRule annotationSAAS annotation, Metal-bindingUniRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Xylose isomeraseUniRule annotation (EC:5.3.1.5UniRule annotation)
Gene namesi
Name:xylAUniRule annotationImported
ORF Names:LBUCD034_0429Imported
OrganismiLactobacillus buchneri CD034Imported
Taxonomic identifieri1071400 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliLactobacillalesLactobacillaceaeLactobacillus
ProteomesiUP000007332: Chromosome

Subcellular locationi

Cytoplasm UniRule annotationSAAS annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

CytoplasmUniRule annotationSAAS annotation

Interactioni

Subunit structurei

Homotetramer.UniRule annotationSAAS annotation

Structurei

3D structure databases

ProteinModelPortaliJ9VZ63.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the xylose isomerase family.UniRule annotation

Phylogenomic databases

KOiK01805.

Family and domain databases

Gene3Di3.20.20.150. 1 hit.
HAMAPiMF_00455. Xylose_isom_A.
InterProiIPR013022. Xyl_isomerase-like_TIM-brl.
IPR013452. Xylose_isom_bac.
IPR001998. Xylose_isomerase.
[Graphical view]
PfamiPF01261. AP_endonuc_2. 1 hit.
[Graphical view]
PRINTSiPR00688. XYLOSISMRASE.
SUPFAMiSSF51658. SSF51658. 1 hit.
TIGRFAMsiTIGR02630. xylose_isom_A. 1 hit.
PROSITEiPS51415. XYLOSE_ISOMERASE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

J9VZ63-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MSYWNVDKIK YVGTGEKKSG LGFQYYNPDE VVGGKKMRDW LRFAVAYWHT
60 70 80 90 100
FDQRLVDPFG DGTAIRPYDK YTDPMDQALA KVDAAFEFYD KLGVDFLCFH
110 120 130 140 150
DRDLAPEGDT LRETNRNLDK VVDKIVENQK TSGMKVLWNT SNLFTNPRFV
160 170 180 190 200
EGAGTSPYAD IFAYSAAQLK HSLEIGKRVG SENYVFWGGR EGYESLWNTD
210 220 230 240 250
MKREQEHAAK LFHMAKDYAN EIGFDAQMLL EPKPKEPTTH QYDFDAATTI
260 270 280 290 300
AFMKEYGLDK DFKLNLEGNH ANLAGHTYQH EIRVAREAGL LGSLDANQGD
310 320 330 340 350
KLIGWDIDEY PSNLYETTAA MTEVVENGSI GPRGGLNFDA KPRRSSFEPN
360 370 380 390 400
DLFYGHIVGM DSFAAGLRVA VAMKNDGVLD DIVKNRYSSF DSGIGADIES
410 420 430 440
GKASMADLEN YSLDKTQKDL RDATHSDHLE EIKDTINHYI IQTLK
Length:445
Mass (Da):50,266
Last modified:November 28, 2012 - v1
Checksum:i52DEC5B25A793D73
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP003043 Genomic DNA. Translation: AFR99528.1.
RefSeqiYP_006725111.1. NC_018610.1.

Genome annotation databases

EnsemblBacteriaiAFR99528; AFR99528; LBUCD034_0429.
GeneIDi13655415.
KEGGilbn:LBUCD034_0429.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP003043 Genomic DNA. Translation: AFR99528.1.
RefSeqiYP_006725111.1. NC_018610.1.

3D structure databases

ProteinModelPortaliJ9VZ63.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAFR99528; AFR99528; LBUCD034_0429.
GeneIDi13655415.
KEGGilbn:LBUCD034_0429.

Phylogenomic databases

KOiK01805.

Family and domain databases

Gene3Di3.20.20.150. 1 hit.
HAMAPiMF_00455. Xylose_isom_A.
InterProiIPR013022. Xyl_isomerase-like_TIM-brl.
IPR013452. Xylose_isom_bac.
IPR001998. Xylose_isomerase.
[Graphical view]
PfamiPF01261. AP_endonuc_2. 1 hit.
[Graphical view]
PRINTSiPR00688. XYLOSISMRASE.
SUPFAMiSSF51658. SSF51658. 1 hit.
TIGRFAMsiTIGR02630. xylose_isom_A. 1 hit.
PROSITEiPS51415. XYLOSE_ISOMERASE. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Insights into the completely annotated genome of Lactobacillus buchneri CD034, a strain isolated from stable grass silage."
    Heinl S., Wibberg D., Eikmeyer F., Szczepanowski R., Blom J., Linke B., Goesmann A., Grabherr R., Schwab H., Puhler A., Schluter A.
    J. Biotechnol. 161:153-166(2012) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: CD034Imported.

Entry informationi

Entry nameiJ9VZ63_LACBU
AccessioniPrimary (citable) accession number: J9VZ63
Entry historyi
Integrated into UniProtKB/TrEMBL: November 28, 2012
Last sequence update: November 28, 2012
Last modified: February 4, 2015
This is version 18 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.