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Protein
Submitted name:

Monomeric isocitrate dehydrogenase

Gene

B739_1889

Organism
Riemerella anatipestifer RA-CH-1
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein predictedi

Functioni

Cofactori

Mg2+UniRule annotation, Mn2+UniRule annotationNote: Binds 1 Mg(2+) or Mn2+ ion per subunit.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei145 – 1451SubstrateUniRule annotation
Sitei255 – 2551Critical for catalysisUniRule annotation
Metal bindingi348 – 3481Magnesium or manganeseUniRule annotation
Sitei418 – 4181Critical for catalysisUniRule annotation
Binding sitei545 – 5451SubstrateUniRule annotation
Metal bindingi546 – 5461Magnesium or manganeseUniRule annotation
Metal bindingi550 – 5501Magnesium or manganeseUniRule annotation

GO - Molecular functioni

  1. isocitrate dehydrogenase (NADP+) activity Source: InterPro
  2. metal ion binding Source: UniProtKB-KW

GO - Biological processi

  1. tricarboxylic acid cycle Source: InterPro
Complete GO annotation...

Keywords - Ligandi

MagnesiumUniRule annotation, Metal-bindingUniRule annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Monomeric isocitrate dehydrogenaseImported
Gene namesi
ORF Names:B739_1889Imported
OrganismiRiemerella anatipestifer RA-CH-1Imported
Taxonomic identifieri1228997 [NCBI]
Taxonomic lineageiBacteriaBacteroidetesFlavobacteriiaFlavobacterialesFlavobacteriaceaeRiemerella
ProteomesiUP000006276: Chromosome

Family & Domainsi

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni132 – 1398Substrate bindingUniRule annotation

Phylogenomic databases

KOiK00031.

Family and domain databases

Gene3Di3.40.718.10. 3 hits.
InterProiIPR004436. Isocitrate_DH_NADP_mono.
IPR024084. IsoPropMal-DH-like_dom.
[Graphical view]
PfamiPF03971. IDH. 1 hit.
[Graphical view]
PIRSFiPIRSF009407. IDH_monmr. 1 hit.
TIGRFAMsiTIGR00178. monomer_idh. 1 hit.

Sequencei

Sequence statusi: Complete.

J9R9T1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSTAKIYYTL TDEAPMLATH SFLPIVKAFT KSADIQIEVP DISLSGRILA
60 70 80 90 100
NFPEVLTEEQ RILDALTQLG ELATKPEANI IKLPNISASI PQLNEAIEEL
110 120 130 140 150
QKKGFNVPNY PAEPKTEEEK EIKAKYAKVL GSAVNPVLRE GNSDRRAPKA
160 170 180 190 200
VKNYAKANPH RIGEWKSDSK TDVAHMNQGD FYGTETSTTV EKDGKFKIVF
210 220 230 240 250
FGNDGSEKVL KDYASLQAGE IIDSSVMNIK ALKTFVKEAI QEAKSRNVLL
260 270 280 290 300
SAHLKATMMK VSDPIIFGAI VETFFQEVFE KYAETFKSLD VNPNDGLASL
310 320 330 340 350
YDKIAGIAQE ADIKADIERV LNESSRVAMV NSDKGITNFH VPSDVIVDAS
360 370 380 390 400
MAALVRGGGK MWNKDGQEED TLAIIPDRSY AGFYQAVIDD MKANGKLDPT
410 420 430 440 450
TMGSVPNVGL MAKKAEEYGS HDKTFQMEAE GTVKVLNENN EVLLEQKVEA
460 470 480 490 500
GDIFRMCQTK DAPIQDWVKL AVNRSRLSDT PAIFWLDKGR AHDREVIKKV
510 520 530 540 550
EQYLKNYDTQ GLDIKILDVK DAMSETLKRA REGKDTISVS GNVLRDYLTD
560 570 580 590 600
LFPILELGTS AKMLSIVPLM NGGGLFETGA GGSAPKHIEQ FIEEGYLRWD
610 620 630 640 650
SLGEFLALQA SLEHLAQTQN NTKAQVLADA LDEANAKFLA NDKSPARKIG
660 670 680 690 700
SIDNRGSHFY LALYWAEALA AQTQDSELST LFQPIAKEMQ ENEAKINEEL
710 720 730
IASQGKAQDI EGYYRPNEDK TYAAMRPSVT LNQIIDRI
Length:738
Mass (Da):81,660
Last modified:November 28, 2012 - v1
Checksum:i5C19A1856AAA51E2
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP003787 Genomic DNA. Translation: AFR36472.1.
RefSeqiWP_014938741.1. NC_018609.1.
YP_006724372.1. NC_018609.1.

Genome annotation databases

EnsemblBacteriaiAFR36472; AFR36472; B739_1889.
GeneIDi13716411.
KEGGirag:B739_1889.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP003787 Genomic DNA. Translation: AFR36472.1.
RefSeqiWP_014938741.1. NC_018609.1.
YP_006724372.1. NC_018609.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAFR36472; AFR36472; B739_1889.
GeneIDi13716411.
KEGGirag:B739_1889.

Phylogenomic databases

KOiK00031.

Family and domain databases

Gene3Di3.40.718.10. 3 hits.
InterProiIPR004436. Isocitrate_DH_NADP_mono.
IPR024084. IsoPropMal-DH-like_dom.
[Graphical view]
PfamiPF03971. IDH. 1 hit.
[Graphical view]
PIRSFiPIRSF009407. IDH_monmr. 1 hit.
TIGRFAMsiTIGR00178. monomer_idh. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. "Riemerella anatipestifer vaccine strains."
    Chun C.A., Shu W.M., Kang Z.D., Jia W.X.
    Submitted (SEP-2012) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: RA-CH-1Imported.

Entry informationi

Entry nameiJ9R9T1_RIEAN
AccessioniPrimary (citable) accession number: J9R9T1
Entry historyi
Integrated into UniProtKB/TrEMBL: November 28, 2012
Last sequence update: November 28, 2012
Last modified: March 4, 2015
This is version 14 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.