Skip Header

You are using a version of Internet Explorer that may not display all features of this website. Please upgrade to a modern browser.
Contribute Send feedback
Read comments (?) or add your own

J9QZP8 (J9QZP8_RIEAN) Unreviewed, UniProtKB/TrEMBL

Last modified February 19, 2014. Version 9. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein namesRecommended name:
D-alanine--D-alanine ligase HAMAP-Rule MF_00047

EC=6.3.2.4 HAMAP-Rule MF_00047
Alternative name(s):
D-Ala-D-Ala ligase HAMAP-Rule MF_00047
D-alanylalanine synthetase HAMAP-Rule MF_00047
Gene names
Name:ddl HAMAP-Rule MF_00047
ORF Names:B739_0293 EMBL AFR34899.1
OrganismRiemerella anatipestifer RA-CH-1 [Complete proteome] EMBL AFR34899.1
Taxonomic identifier1228997 [NCBI]
Taxonomic lineageBacteriaBacteroidetesFlavobacteriiaFlavobacterialesFlavobacteriaceaeRiemerella

Protein attributes

Sequence length327 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Cell wall formation By similarity. HAMAP-Rule MF_00047 SAAS SAAS005905

Catalytic activity

ATP + 2 D-alanine = ADP + phosphate + D-alanyl-D-alanine. HAMAP-Rule MF_00047 SAAS SAAS005905

Cofactor

Binds 2 magnesium or manganese ions per subunit By similarity. HAMAP-Rule MF_00047 SAAS SAAS005905

Pathway

Cell wall biogenesis; peptidoglycan biosynthesis. HAMAP-Rule MF_00047 SAAS SAAS005905

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00047 SAAS SAAS005905.

Sequence similarities

Belongs to the D-alanine--D-alanine ligase family. HAMAP-Rule MF_00047

Contains 1 ATP-grasp domain. HAMAP-Rule MF_00047

Contains ATP-grasp domain. SAAS SAAS005905

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Domain123 – 322200ATP-grasp By similarity HAMAP-Rule MF_00047
Nucleotide binding151 – 20656ATP By similarity HAMAP-Rule MF_00047

Sites

Metal binding2771Magnesium or manganese 1 By similarity HAMAP-Rule MF_00047
Metal binding2891Magnesium or manganese 1 By similarity HAMAP-Rule MF_00047
Metal binding2891Magnesium or manganese 2 By similarity HAMAP-Rule MF_00047
Metal binding2911Magnesium or manganese 2 By similarity HAMAP-Rule MF_00047

Sequences

Sequence LengthMass (Da)Tools
J9QZP8 [UniParc].

Last modified November 28, 2012. Version 1.
Checksum: EC8DC8648D5C8D47

FASTA32736,391
        10         20         30         40         50         60 
MSKKNIAVVM GGYSDEYKVS LKSGQLIYDS LDRDLYNVYK VVVLKEGWFY LDENEAKLPI 

        70         80         90        100        110        120 
QKGDFSVNLP SGEVLRFDVC FNTIHGTPGE NGVLQAYWDA IGQKYTGCDF YQSALTFNKK 

       130        140        150        160        170        180 
DTLAVLAKYG IPSAKSFYIK KGEAYDKDEI INELKLPLFV KPNQSGSSLG ISKVKEASEF 

       190        200        210        220        230        240 
EAALEKAFLE DDEVLVESFL DGMEVSVGVL DYKGETIVLG ITEIIPETEF FDYEAKYQGA 

       250        260        270        280        290        300 
SQEITPARLD EATKLRVEEV AKRAYNSLGM KGFSRSEYII MGGVPYMLEM NTNPGFSPAS 

       310        320 
ILPQQARIYG ISIKDLCGNE VEKALAK 

« Hide

References

[1]"Riemerella anatipestifer vaccine strains."
Chun C.A., Shu W.M., Kang Z.D., Jia W.X.
Submitted (SEP-2012) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE.
Strain: RA-CH-1 EMBL AFR34899.1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP003787 Genomic DNA. Translation: AFR34899.1.
RefSeqYP_006722798.1. NC_018609.1.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAFR34899; AFR34899; B739_0293.
GeneID13716783.
KEGGrag:B739_0293.

Organism-specific databases

CMRSearch...

Phylogenomic databases

KOK01921.

Enzyme and pathway databases

UniPathwayUPA00219.

Family and domain databases

Gene3D3.30.1490.20. 1 hit.
3.30.470.20. 2 hits.
3.40.50.20. 1 hit.
HAMAPMF_00047. Dala_Dala_lig.
InterProIPR011761. ATP-grasp.
IPR013815. ATP_grasp_subdomain_1.
IPR013816. ATP_grasp_subdomain_2.
IPR000291. D-Ala_lig_Van_CS.
IPR005905. D_ala_D_ala.
IPR011095. Dala_Dala_lig_C.
IPR011127. Dala_Dala_lig_N.
IPR016185. PreATP-grasp_dom.
[Graphical view]
PANTHERPTHR23132. PTHR23132. 1 hit.
PfamPF07478. Dala_Dala_lig_C. 1 hit.
PF01820. Dala_Dala_lig_N. 1 hit.
[Graphical view]
SUPFAMSSF52440. SSF52440. 1 hit.
TIGRFAMsTIGR01205. D_ala_D_alaTIGR. 1 hit.
PROSITEPS50975. ATP_GRASP. 1 hit.
PS00843. DALA_DALA_LIGASE_1. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameJ9QZP8_RIEAN
AccessionPrimary (citable) accession number: J9QZP8
Entry history
Integrated into UniProtKB/TrEMBL: November 28, 2012
Last sequence update: November 28, 2012
Last modified: February 19, 2014
This is version 9 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)