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Protein
Submitted name:

Uncharacterized protein

Gene

HK1

Organism
Canis lupus familiaris (Dog) (Canis familiaris)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein inferred from homologyi

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

KinaseSAAS annotation, Transferase

Keywords - Biological processi

GlycolysisSAAS annotation

Keywords - Ligandi

ATP-bindingSAAS annotation, Nucleotide-binding

Enzyme and pathway databases

ReactomeiR-CFA-70153. Glucose transport.
R-CFA-70171. Glycolysis.

Names & Taxonomyi

Protein namesi
Submitted name:
Uncharacterized proteinImported
Gene namesi
Name:HK1Imported
OrganismiCanis lupus familiaris (Dog) (Canis familiaris)Imported
Taxonomic identifieri9615 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCarnivoraCaniformiaCanidaeCanis
Proteomesi
  • UP000002254 Componenti: Chromosome 4

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

PTM / Processingi

Proteomic databases

PaxDbiJ9PBL1.

Interactioni

Protein-protein interaction databases

STRINGi9615.ENSCAFP00000020540.

Structurei

3D structure databases

ProteinModelPortaliJ9PBL1.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini22 – 219198Hexokinase_1InterPro annotationAdd
BLAST
Domaini225 – 459235Hexokinase_2InterPro annotationAdd
BLAST
Domaini470 – 667198Hexokinase_1InterPro annotationAdd
BLAST
Domaini673 – 907235Hexokinase_2InterPro annotationAdd
BLAST

Sequence similaritiesi

Belongs to the hexokinase family.SAAS annotation

Phylogenomic databases

eggNOGiKOG1369. Eukaryota.
COG5026. LUCA.
GeneTreeiENSGT00390000017159.

Family and domain databases

InterProiIPR001312. Hexokinase.
IPR019807. Hexokinase_BS.
IPR022673. Hexokinase_C.
IPR022672. Hexokinase_N.
[Graphical view]
PANTHERiPTHR19443. PTHR19443. 1 hit.
PfamiPF00349. Hexokinase_1. 2 hits.
PF03727. Hexokinase_2. 2 hits.
[Graphical view]
PROSITEiPS00378. HEXOKINASE_1. 2 hits.
PS51748. HEXOKINASE_2. 2 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

J9PBL1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MIAAQLLAYY FTELKDDQVK KIDKYLYAMR LSDETLIDIM TRFKKEMKNG
60 70 80 90 100
LSRDFNPTAT VKMLPTFVRS IPDGSEKGDF IALDLGGSSF RILRVQVNHE
110 120 130 140 150
QNQNVHMESE IYDTPENIVH GSGSQLFDHV AECLGDFMEK KKIKDKKLPV
160 170 180 190 200
GFTFSFPCRQ SKIDEGILIT WTKKFKASGV EGMDVVKLLN KAIKKRGDYD
210 220 230 240 250
ANIVAVVNDT VGTMMTCGYD DQQCEVGLII GTGTNACYME ELRHIDLVEG
260 270 280 290 300
DEGRMCINTE WGAFGDDGSL EDIRTEFDRE IDRGSLNPGK QLFEKMVSGM
310 320 330 340 350
YLGELVRLIL VKMAKESLLF EGRITPELLT RGKLKTSDVS AIEKNKEGLH
360 370 380 390 400
NAKEILTRLG VEPSDDDCIS VQHVCTIVSF RSANLVAATL GAILNRLRDN
410 420 430 440 450
KGTPRLRTTV GVDGSLYKTH PQYARRFHKT LRRLVPDSDV RFLLSESGSG
460 470 480 490 500
KGAAMVTAVA YRLAEQHRQI EETLAHFRLT KDMLLEVKKR MRTEMDMGLR
510 520 530 540 550
KQTHEKAVVK MLPSFVRSTP DGTEHGDFLA LDLGGTNFRV LLVKIRSGKK
560 570 580 590 600
RTVEMHNKIY AIPIEIMQGT GEELFDHIVS CISDFLDYMG IKGPKMPLGF
610 620 630 640 650
TFSFPCKQTS LDAGILITWT KGFKATDCVG NDVATLLREA IKRREEFDLD
660 670 680 690 700
VVAVVNDTVG TMMTCAYEEP TCEVGLIVGT GSNACYMEEM KNVEMLEGND
710 720 730 740 750
GRMCINMEWG AFGDNGCLDD IRTIYDRLVD EYSLNAGKQR FEKMISGMYL
760 770 780 790 800
GEIVRNILID FTKKGFLFRG QISETLKTRG IFQTKYLSQI ESDRLALLQV
810 820 830 840 850
RAILQQLGLN STCDDSILVK TVCGVVSKRA AQLCGAGMAA VVDKIRENRG
860 870 880 890 900
LDHLNVTVGV DGTLYKLHPH FSRIMYQTVK ELSPKCNVSF LLSEDGSGKG
910
AALITAVGVR LREETSS
Length:917
Mass (Da):102,500
Last modified:October 31, 2012 - v1
Checksum:iF40B46635C89F515
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AAEX03002787 Genomic DNA. No translation available.
RefSeqiXP_536376.3. XM_536376.4.

Genome annotation databases

EnsembliENSCAFT00000045763; ENSCAFP00000043192; ENSCAFG00000013917.
GeneIDi479234.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AAEX03002787 Genomic DNA. No translation available.
RefSeqiXP_536376.3. XM_536376.4.

3D structure databases

ProteinModelPortaliJ9PBL1.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9615.ENSCAFP00000020540.

Proteomic databases

PaxDbiJ9PBL1.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSCAFT00000045763; ENSCAFP00000043192; ENSCAFG00000013917.
GeneIDi479234.

Organism-specific databases

CTDi3098.

Phylogenomic databases

eggNOGiKOG1369. Eukaryota.
COG5026. LUCA.
GeneTreeiENSGT00390000017159.

Enzyme and pathway databases

ReactomeiR-CFA-70153. Glucose transport.
R-CFA-70171. Glycolysis.

Family and domain databases

InterProiIPR001312. Hexokinase.
IPR019807. Hexokinase_BS.
IPR022673. Hexokinase_C.
IPR022672. Hexokinase_N.
[Graphical view]
PANTHERiPTHR19443. PTHR19443. 1 hit.
PfamiPF00349. Hexokinase_1. 2 hits.
PF03727. Hexokinase_2. 2 hits.
[Graphical view]
PROSITEiPS00378. HEXOKINASE_1. 2 hits.
PS51748. HEXOKINASE_2. 2 hits.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiJ9PBL1_CANLF
AccessioniPrimary (citable) accession number: J9PBL1
Entry historyi
Integrated into UniProtKB/TrEMBL: October 31, 2012
Last sequence update: October 31, 2012
Last modified: September 7, 2016
This is version 32 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.