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Protein

Phosphoenolpyruvate carboxylase

Gene

ppc

Organism
Morganella morganii subsp. morganii KT
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.UniRule annotation

Catalytic activityi

Phosphate + oxaloacetate = H2O + phosphoenolpyruvate + HCO3-.UniRule annotationSAAS annotation

Cofactori

Mg2+UniRule annotationSAAS annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei137 – 1371UniRule annotation
Active sitei544 – 5441UniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

LyaseUniRule annotationSAAS annotation

Keywords - Biological processi

Carbon dioxide fixationUniRule annotationSAAS annotation

Keywords - Ligandi

MagnesiumUniRule annotationSAAS annotation, PyruvateImported

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoenolpyruvate carboxylaseUniRule annotationSAAS annotation (EC:4.1.1.31UniRule annotationSAAS annotation)
Short name:
PEPCUniRule annotation
Short name:
PEPCaseUniRule annotation
Gene namesi
Name:ppcUniRule annotation
ORF Names:MU9_593Imported
OrganismiMorganella morganii subsp. morganii KTImported
Taxonomic identifieri1124991 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeMorganella
ProteomesiUP000011834 Componenti: Chromosome

Interactioni

Subunit structurei

Homotetramer.UniRule annotation

Family & Domainsi

Sequence similaritiesi

Belongs to the PEPCase type 1 family.UniRule annotation

Phylogenomic databases

KOiK01595.

Family and domain databases

HAMAPiMF_00595. PEPcase_type1.
InterProiIPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view]
PfamiPF00311. PEPcase. 1 hit.
[Graphical view]
PRINTSiPR00150. PEPCARBXLASE.
SUPFAMiSSF51621. SSF51621. 1 hit.
PROSITEiPS00781. PEPCASE_1. 1 hit.
PS00393. PEPCASE_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

J7SKH2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNQQYSAMRS NVSMLGKLLG DTIKEAQGEH ILEKVESIRK LSKASQAGNE
60 70 80 90 100
IQRQKLLMTL QNLSNEELLP VARAFNQFLN LTNVAEQYHS ISPHGEAASN
110 120 130 140 150
PVALAALFDQ LKAKNFTNEE MRKAVDELSI ELVLTAHPTE IARRTLIHKL
160 170 180 190 200
VAVNTCLAQL DHDDLADYEH DRIMRRLRQL VAQAWHTDEI RKDRPTPLDE
210 220 230 240 250
AKWGFAVVEN SLWEGVPAFL REFNEQLEAS LDYNLSVEAT PIRFTSWMGG
260 270 280 290 300
DRDGNPNVTA DITRRVLTLS RWKAADLFYN DIQVLVSELS MSECTPELRE
310 320 330 340 350
RVGEDAAEPY RVITKQLRAR LKSTLDYLER CLAGEPAIKP DNLLTDNEEL
360 370 380 390 400
WEPLYLCYRS LVECGMKIIA NGQLLDTLRR IRCFGLQLVR IDVRQESTRH
410 420 430 440 450
TEALSELTQY LGLGDYAAWP EEEKQEFLLR ELQSKRPLVP QNWECSNETR
460 470 480 490 500
EVFDTCRVIA ESPENSVASY VISMAKVPSD VLAVKLLLKE SGSPVTLPVA
510 520 530 540 550
PLFETLDDLN NAESVITRLL SIDWYRNLIN DRQMVMIGYS DSAKDAGVMA
560 570 580 590 600
ASWAQYRAQD ALIKVCAREG VTLTLFHGRG GTIGRGGAPA HAALLSQPPG
610 620 630 640 650
SLKGGLRVTE QGEMIRFKFG LPQVTISSLA MYASASLEAN LLPPPEPKPE
660 670 680 690 700
WAAIMDRLSD ISCEMYRDYV REQPDFVPYF RAATPEQELG KLPLGSRPAK
710 720 730 740 750
RRPTGGVETL RAIPWIFAWS QNRLMLPAWL GAGAALKTAV DEGNRAMLEV
760 770 780 790 800
MYYQWPFFRT RIGMLEMVFA KVDLWLAEYY DQRLVEPRLW PLGAKLREQL
810 820 830 840 850
SQDIKSVLMI SKDEQLMADL PWIAESIALR NVYTDPLNVL QAELLHRSRE
860 870
CDQSDPQVEQ ALMVTIAGIA AGMRNTG
Length:877
Mass (Da):98,987
Last modified:October 31, 2012 - v1
Checksum:iAC6E4CB063EFEFF7
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP004345 Genomic DNA. Translation: AGG29639.1.
RefSeqiWP_004236599.1. NC_020418.1.

Genome annotation databases

EnsemblBacteriaiAGG29639; AGG29639; MU9_593.
KEGGimmk:MU9_593.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP004345 Genomic DNA. Translation: AGG29639.1.
RefSeqiWP_004236599.1. NC_020418.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAGG29639; AGG29639; MU9_593.
KEGGimmk:MU9_593.

Phylogenomic databases

KOiK01595.

Family and domain databases

HAMAPiMF_00595. PEPcase_type1.
InterProiIPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view]
PfamiPF00311. PEPcase. 1 hit.
[Graphical view]
PRINTSiPR00150. PEPCARBXLASE.
SUPFAMiSSF51621. SSF51621. 1 hit.
PROSITEiPS00781. PEPCASE_1. 1 hit.
PS00393. PEPCASE_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Whole-genome sequencing and identification of Morganella morganii KT pathogenicity-related genes."
    Chen Y.T., Peng H.L., Shia W.C., Hsu F.R., Ken C.F., Tsao Y.M., Chen C.H., Liu C.E., Hsieh M.F., Chen H.C., Tang C.Y., Ku T.H.
    BMC Genomics 13:S4-S4(2012) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: KTImported.

Entry informationi

Entry nameiJ7SKH2_MORMO
AccessioniPrimary (citable) accession number: J7SKH2
Entry historyi
Integrated into UniProtKB/TrEMBL: October 31, 2012
Last sequence update: October 31, 2012
Last modified: May 27, 2015
This is version 22 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.