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J7S1R4 (J7S1R4_CAMJE) Unreviewed, UniProtKB/TrEMBL

Last modified May 1, 2013. Version 7. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Protein attributes

Sequence length346 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Cell wall formation By similarity. SAAS SAAS005905 HAMAP-Rule MF_00047

Catalytic activity

ATP + 2 D-alanine = ADP + phosphate + D-alanyl-D-alanine. SAAS SAAS005905 HAMAP-Rule MF_00047

Cofactor

Binds 2 magnesium or manganese ions per subunit By similarity. SAAS SAAS005905 HAMAP-Rule MF_00047

Pathway

Cell wall biogenesis; peptidoglycan biosynthesis. SAAS SAAS005905 HAMAP-Rule MF_00047

Subcellular location

Cytoplasm By similarity SAAS SAAS005905 HAMAP-Rule MF_00047.

Sequence similarities

Belongs to the D-alanine--D-alanine ligase family. HAMAP-Rule MF_00047

Contains 1 ATP-grasp domain. SAAS SAAS005905 HAMAP-Rule MF_00047

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Domain133 – 327195ATP-grasp By similarity HAMAP-Rule MF_00047
Nucleotide binding159 – 21153ATP By similarity HAMAP-Rule MF_00047

Sites

Metal binding2841Magnesium or manganese 1 By similarity HAMAP-Rule MF_00047
Metal binding2961Magnesium or manganese 1 By similarity HAMAP-Rule MF_00047
Metal binding2961Magnesium or manganese 2 By similarity HAMAP-Rule MF_00047
Metal binding2981Magnesium or manganese 2 By similarity HAMAP-Rule MF_00047

Sequences

Sequence LengthMass (Da)Tools
J7S1R4 [UniParc].

Last modified October 31, 2012. Version 1.
Checksum: 50296AD08284B473

FASTA34639,908
        10         20         30         40         50         60 
MKFAILFGGN SYEHEISIVS AVVLKKVINQ NLEFIFCDEE RRFYHIPSEK MNSKTFSTKA 

        70         80         90        100        110        120 
YKKEKELFIK QGGFFSKGFL KENKLECECV INLIHGRDGE DGKIAALFEF YSIKFIGPRL 

       130        140        150        160        170        180 
EASVLSFNKE LTKLYAKSVG VKTLDYTILR KNQNSKEKLS FPCIIKPARL GSSIGISIVK 

       190        200        210        220        230        240 
DEKDLEYAKD VGFEFDNDLV VEEFKNNIKE YNLAGCMIND EFVFSIIEEP KKKEFLDFEQ 

       250        260        270        280        290        300 
KYLSFSGHNE LIEADLSEEL KEKLKDSFKK IYNPLFKGAL IRCDFFILDN EIYLNEINPN 

       310        320        330        340 
PGSLANYLFK DFNTTLNALA DQISLEKMIK INYNFLHSIN GQKGKL 

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References

[1]"Complete Genome Sequence of a Variant of Campylobacter jejuni NCTC 11168."
Revez J., Schott T., Rossi M., Hanninen M.L.
J. Bacteriol. 194:6298-6299(2012)
Cited for: NUCLEOTIDE SEQUENCE.
Strain: NCTC 11168-BN148 EMBL CCK66903.1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
HE978252 Genomic DNA. Translation: CCK66903.1.
RefSeqYP_006632954.1. NC_018521.1.

3D structure databases

ProteinModelPortalJ7S1R4.
SMRJ7S1R4. Positions 1-323.
ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaCCK66903; CCK66903; BN148_0798c.
GeneID13532025.
KEGGcjb:BN148_0798c.

Phylogenomic databases

KOK01921.
OMAIMIRASD.

Enzyme and pathway databases

UniPathwayUPA00219.

Family and domain databases

Gene3D3.30.1490.20. 1 hit.
3.30.470.20. 2 hits.
3.40.50.20. 1 hit.
HAMAPMF_00047. Dala_Dala_lig.
InterProIPR011761. ATP-grasp.
IPR013815. ATP_grasp_subdomain_1.
IPR013816. ATP_grasp_subdomain_2.
IPR000291. D-Ala_lig_Van_CS.
IPR005905. D_ala_D_ala.
IPR011095. Dala_Dala_lig_C.
IPR011127. Dala_Dala_lig_N.
IPR016185. PreATP-grasp_dom.
[Graphical view]
PANTHERPTHR23132. PTHR23132. 1 hit.
PfamPF07478. Dala_Dala_lig_C. 1 hit.
PF01820. Dala_Dala_lig_N. 1 hit.
[Graphical view]
SUPFAMSSF52440. PreATP-grasp-like. 1 hit.
TIGRFAMsTIGR01205. D_ala_D_alaTIGR. 1 hit.
PROSITEPS50975. ATP_GRASP. 1 hit.
PS00843. DALA_DALA_LIGASE_1. 1 hit.
PS00844. DALA_DALA_LIGASE_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameJ7S1R4_CAMJE
AccessionPrimary (citable) accession number: J7S1R4
Entry history
Integrated into UniProtKB/TrEMBL: October 31, 2012
Last sequence update: October 31, 2012
Last modified: May 1, 2013
This is version 7 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)