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J7RXX5

- J7RXX5_STREE

UniProt

J7RXX5 - J7RXX5_STREE

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Protein

Elongation factor Tu

Gene

tufA

Organism
Streptococcus pneumoniae SPNA45
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.UniRule annotation

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi19 – 268GTPUniRule annotation
Nucleotide bindingi84 – 885GTPUniRule annotation
Nucleotide bindingi139 – 1424GTPUniRule annotation

GO - Molecular functioni

  1. GTPase activity Source: InterPro
  2. GTP binding Source: UniProtKB-HAMAP
  3. translation elongation factor activity Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Elongation factorUniRule annotation

Keywords - Biological processi

Protein biosynthesis

Keywords - Ligandi

GTP-bindingUniRule annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Elongation factor TuUniRule annotation
Short name:
EF-TuUniRule annotation
Gene namesi
Name:tufAImported
Synonyms:tufUniRule annotation
ORF Names:SPNA45_00729Imported
OrganismiStreptococcus pneumoniae SPNA45Imported
Taxonomic identifieri869309 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliLactobacillalesStreptococcaceaeStreptococcus
ProteomesiUP000003992: Chromosome

Subcellular locationi

Cytoplasm UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

CytoplasmUniRule annotation

PTM / Processingi

Proteomic databases

PRIDEiJ7RXX5.

Interactioni

Subunit structurei

Monomer.UniRule annotation

Structurei

3D structure databases

ProteinModelPortaliJ7RXX5.
SMRiJ7RXX5. Positions 2-396.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.UniRule annotation

Phylogenomic databases

KOiK02358.

Family and domain databases

Gene3Di3.40.50.300. 1 hit.
HAMAPiMF_00118_B. EF_Tu_B.
InterProiIPR000795. EF_GTP-bd_dom.
IPR027417. P-loop_NTPase.
IPR005225. Small_GTP-bd_dom.
IPR009000. Transl_B-barrel.
IPR009001. Transl_elong_EF1A/Init_IF2_C.
IPR004161. Transl_elong_EFTu/EF1A_2.
IPR004541. Transl_elong_EFTu/EF1A_bac/org.
IPR004160. Transl_elong_EFTu/EF1A_C.
[Graphical view]
PfamiPF00009. GTP_EFTU. 1 hit.
PF03144. GTP_EFTU_D2. 1 hit.
PF03143. GTP_EFTU_D3. 1 hit.
[Graphical view]
PRINTSiPR00315. ELONGATNFCT.
SUPFAMiSSF50447. SSF50447. 1 hit.
SSF50465. SSF50465. 1 hit.
SSF52540. SSF52540. 1 hit.
TIGRFAMsiTIGR00485. EF-Tu. 1 hit.
TIGR00231. small_GTP. 1 hit.
PROSITEiPS00301. EFACTOR_GTP. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

J7RXX5-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MAKEKYDRSK PHVNIGTIGH VDHGKTTLTA AITTVLARRL PSSVNQPKDY
60 70 80 90 100
ASIDAAPEER ERGITINTAH VEYETEKRHY AHIDAPGHAD YVKNMITGAA
110 120 130 140 150
QMDGAILVVA STDGPMPQTR EHILLSRQVG VKHLIVFMNK VDLVDDEELL
160 170 180 190 200
ELVEMEIRDL LSEYDFPGDD LPVIQGSALK ALEGDSKYED IVMELMNTVD
210 220 230 240 250
EYIPEPERDT DKPLLLPVED VFSITGRGTV ASGRIDRGIV KVNDEIEIVG
260 270 280 290 300
IKEETQKAVV TGVEMFRKQL DEGLAGDNVG VLLRGVQRDE IERGQVIAKP
310 320 330 340 350
GSINPHTKFK GEVYILTKEE GGRHTPFFNN YRPQFYFRTT DVTGSIELPA
360 370 380 390
GTEMVMPGDN VTIDVELIHP IAVEQGTTFS IREGGRTVGS GMVTEIEA
Length:398
Mass (Da):43,971
Last modified:October 31, 2012 - v1
Checksum:i5CB2F8F5FA5101A0
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
HE983624 Genomic DNA. Translation: CCM08017.1.
RefSeqiYP_006701196.1. NC_018594.1.

Genome annotation databases

EnsemblBacteriaiCCM08017; CCM08017; SPNA45_00729.
GeneIDi13652077.
KEGGisnu:SPNA45_00729.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
HE983624 Genomic DNA. Translation: CCM08017.1 .
RefSeqi YP_006701196.1. NC_018594.1.

3D structure databases

ProteinModelPortali J7RXX5.
SMRi J7RXX5. Positions 2-396.
ModBasei Search...
MobiDBi Search...

Proteomic databases

PRIDEi J7RXX5.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai CCM08017 ; CCM08017 ; SPNA45_00729 .
GeneIDi 13652077.
KEGGi snu:SPNA45_00729.

Phylogenomic databases

KOi K02358.

Family and domain databases

Gene3Di 3.40.50.300. 1 hit.
HAMAPi MF_00118_B. EF_Tu_B.
InterProi IPR000795. EF_GTP-bd_dom.
IPR027417. P-loop_NTPase.
IPR005225. Small_GTP-bd_dom.
IPR009000. Transl_B-barrel.
IPR009001. Transl_elong_EF1A/Init_IF2_C.
IPR004161. Transl_elong_EFTu/EF1A_2.
IPR004541. Transl_elong_EFTu/EF1A_bac/org.
IPR004160. Transl_elong_EFTu/EF1A_C.
[Graphical view ]
Pfami PF00009. GTP_EFTU. 1 hit.
PF03144. GTP_EFTU_D2. 1 hit.
PF03143. GTP_EFTU_D3. 1 hit.
[Graphical view ]
PRINTSi PR00315. ELONGATNFCT.
SUPFAMi SSF50447. SSF50447. 1 hit.
SSF50465. SSF50465. 1 hit.
SSF52540. SSF52540. 1 hit.
TIGRFAMsi TIGR00485. EF-Tu. 1 hit.
TIGR00231. small_GTP. 1 hit.
PROSITEi PS00301. EFACTOR_GTP. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Structure and dynamics of the pan-genome of Streptococcus pneumoniae and closely related species."
    Donati C., Hiller N.L., Tettelin H., Muzzi A., Croucher N.J., Angiuoli S.V., Oggioni M., Dunning Hotopp J.C., Hu F.Z., Riley D., Covacci A., Mitchell T.J., Bentley S.D., Kilian M., Ehrlich G.D., Rappuoli R., Moxon E.R., Masignani V.
    Submitted (SEP-2012) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: A45Imported.
  2. Aslett M.
    Submitted (SEP-2012) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: A45Imported.

Entry informationi

Entry nameiJ7RXX5_STREE
AccessioniPrimary (citable) accession number: J7RXX5
Entry historyi
Integrated into UniProtKB/TrEMBL: October 31, 2012
Last sequence update: October 31, 2012
Last modified: October 29, 2014
This is version 16 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

External Data

Dasty 3