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J7RFV2 (J7RFV2_BORP1) Unreviewed, UniProtKB/TrEMBL

Last modified July 9, 2014. Version 13. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Protein attributes

Sequence length387 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Function

Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids By similarity. HAMAP-Rule MF_01201

Catalytic activity

L-alanine = D-alanine. HAMAP-Rule MF_01201 SAAS SAAS020622

Cofactor

Pyridoxal phosphate By similarity. HAMAP-Rule MF_01201 SAAS SAAS020622

Pathway

Amino-acid biosynthesis; D-alanine biosynthesis; D-alanine from L-alanine: step 1/1. HAMAP-Rule MF_01201

Sequence similarities

Belongs to the alanine racemase family. HAMAP-Rule MF_01201 RuleBase RU004188

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Active site491Proton acceptor; specific for D-alanine By similarity HAMAP-Rule MF_01201
Active site2721Proton acceptor; specific for L-alanine By similarity HAMAP-Rule MF_01201
Binding site1441Substrate By similarity HAMAP-Rule MF_01201
Binding site3201Substrate; via amide nitrogen By similarity HAMAP-Rule MF_01201

Amino acid modifications

Modified residue491N6-(pyridoxal phosphate)lysine By similarity HAMAP-Rule MF_01201

Sequences

Sequence LengthMass (Da)Tools
J7RFV2 [UniParc].

Last modified October 31, 2012. Version 1.
Checksum: 1BBEF8845C6AD15A

FASTA38741,211
        10         20         30         40         50         60 
MPLASDPFDA PIPGLHACID PIAVAHNLEV LRQRLGVGVD GPRIWATVKA DAYGHGLHNV 

        70         80         90        100        110        120 
LPGLRAADGI AVRHLHEAHQ CRRVGWSGPI MVYAGLTHER EAALLTLQQL HLVITDMTQL 

       130        140        150        160        170        180 
EWLPGKPLYS CAPWVWLRYI GATRLGGLDA SEYRCAYARC RELQQHGALR GVGHLNHYAN 

       190        200        210        220        230        240 
AASVGDLERE HADFEACIRG LPGPVSTCNS AAACVLPTMA ARTDWVRPGL ALYGVSPIPG 

       250        260        270        280        290        300 
RAGRDLGLRP AMTLRSTLCA TQNLPAGASV GYGCTFVADQ PMALGLVRCG YGDGYPHNPR 

       310        320        330        340        350        360 
ASFPVQVDGV LTRTVGRISM DLMAVDLRPI PAAARGAPVV LWGSPQLPVE HIAHAAGTIA 

       370        380 
AELLTGLTAR VPLMRADHAA LLRGPPA 

« Hide

References

[1]"Comparative genomics of the classical Bordetella subspecies: the evolution and exchange of virulence-associated diversity amongst closely related pathogens."
Park J., Zhang Y., Buboltz A.M., Zhang X., Schuster S.C., Ahuja U., Liu M., Miller J.F., Sebaihia M., Bentley S.D., Parkhill J., Harvill E.T.
BMC Genomics 13:545-545(2012) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 9797 / DSM 5571 / NCTC 10739 / 18323.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
HE965805 Genomic DNA. Translation: CCJ62265.1.
RefSeqYP_006625550.1. NC_018518.1.

3D structure databases

ProteinModelPortalJ7RFV2.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaCCJ62265; CCJ62265; BN118_0840.
GeneID13801130.
KEGGbper:BN118_0840.

Organism-specific databases

CMRSearch...

Phylogenomic databases

KOK01775.

Enzyme and pathway databases

UniPathwayUPA00042; UER00497.

Family and domain databases

Gene3D2.40.37.10. 1 hit.
3.20.20.10. 1 hit.
HAMAPMF_01201. Ala_racemase.
InterProIPR000821. Ala_racemase.
IPR009006. Ala_racemase/Decarboxylase_C.
IPR011079. Ala_racemase_C.
IPR001608. Ala_racemase_N.
IPR020622. Ala_racemase_pyridoxalP-BS.
IPR029066. PLP-binding_barrel.
[Graphical view]
PfamPF00842. Ala_racemase_C. 1 hit.
PF01168. Ala_racemase_N. 1 hit.
[Graphical view]
PRINTSPR00992. ALARACEMASE.
SMARTSM01005. Ala_racemase_C. 1 hit.
[Graphical view]
SUPFAMSSF50621. SSF50621. 1 hit.
SSF51419. SSF51419. 1 hit.
TIGRFAMsTIGR00492. alr. 1 hit.
PROSITEPS00395. ALANINE_RACEMASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameJ7RFV2_BORP1
AccessionPrimary (citable) accession number: J7RFV2
Entry history
Integrated into UniProtKB/TrEMBL: October 31, 2012
Last sequence update: October 31, 2012
Last modified: July 9, 2014
This is version 13 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)