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Protein

ATP-dependent RNA helicase RhlE

Gene

rhlE

Organism
Escherichia coli
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

DEAD-box RNA helicase involved in ribosome assembly. Has RNA-dependent ATPase activity and unwinds double-stranded RNA.UniRule annotation

Catalytic activityi

ATP + H2O = ADP + phosphate.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionHelicaseUniRule annotationImported, Hydrolase
Biological processRibosome biogenesisUniRule annotation
LigandATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
ATP-dependent RNA helicase RhlEUniRule annotation (EC:3.6.4.13UniRule annotation)
Gene namesi
Name:rhlEUniRule annotationImported
ORF Names:A8C65_10105Imported, A9R57_22115Imported, AC789_1c08310Imported, ACN002_0829Imported, ACU57_05775Imported, AM266_20870Imported, AUQ13_15340Imported, B1K96_12305Imported, BHS81_04860Imported, BHS87_04235Imported, BJJ90_17895Imported, BMT91_14960Imported, BN17_05961Imported, BUE81_13710Imported, BVL39_24530Imported, BW690_02975Imported, BZL31_11445Imported, C2U48_06065Imported, CA593_25135Imported, CR534_18215Imported, CR538_17445Imported, CRM83_11380Imported, CRT55_20740Imported, CU078_06850Imported, CWS33_06755Imported, CXB56_19720Imported, EC1094V2_3083Imported, EC3234A_13c00160Imported, EL75_2997Imported, EL79_3087Imported, EL80_3048Imported, ERS085365_01677Imported, ERS085374_03879Imported, ERS085416_03983Imported, ERS139211_03961Imported, ERS150873_00286Imported, HW43_07695Imported, PGD_02537Imported, RG28_00545Imported, RK56_000585Imported, RX35_02486Imported, SK85_00799Imported, WQ89_21215Imported
OrganismiEscherichia coliImported
Taxonomic identifieri562 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000233549 Componenti: Unassembled WGS sequence
  • UP000044893 Componenti: Unassembled WGS sequence
  • UP000230908 Componenti: Chromosome
  • UP000236496 Componenti: Unassembled WGS sequence
  • UP000215493 Componenti: Unassembled WGS sequence
  • UP000193530 Componenti: Unassembled WGS sequence
  • UP000194908 Componenti: Unassembled WGS sequence
  • UP000030018 Componenti: Unassembled WGS sequence
  • UP000030000 Componenti: Unassembled WGS sequence
  • UP000066343 Componenti: Chromosome
  • UP000038112 Componenti: Unassembled WGS sequence
  • UP000188724 Componenti: Unassembled WGS sequence
  • UP000070045 Componenti: Unassembled WGS sequence
  • UP000234324 Componenti: Chromosome
  • UP000184379 Componenti: Chromosome
  • UP000094022 Componenti: Unassembled WGS sequence
  • UP000194285 Componenti: Unassembled WGS sequence
  • UP000042305 Componenti: Unassembled WGS sequence
  • UP000193168 Componenti: Unassembled WGS sequence
  • UP000040934 Componenti: Unassembled WGS sequence
  • UP000234906 Componenti: Chromosome
  • UP000234238 Componenti: Chromosome
  • UP000185422 Componenti: Chromosome
  • UP000036012 Componenti: Unassembled WGS sequence
  • UP000236587 Componenti: Chromosome
  • UP000051850 Componenti: Unassembled WGS sequence
  • UP000220282 Componenti: Unassembled WGS sequence
  • UP000186204 Componenti: Unassembled WGS sequence
  • UP000235136 Componenti: Chromosome
  • UP000050556 Componenti: Unassembled WGS sequence
  • UP000188855 Componenti: Unassembled WGS sequence
  • UP000233768 Componenti: Chromosome iv
  • UP000031522 Componenti: Chromosome
  • UP000196822 Componenti: Unassembled WGS sequence
  • UP000030783 Componenti: Chromosome
  • UP000029988 Componenti: Unassembled WGS sequence
  • UP000095183 Componenti: Unassembled WGS sequence
  • UP000077380 Componenti: Unassembled WGS sequence
  • UP000194199 Componenti: Chromosome
  • UP000041959 Componenti: Unassembled WGS sequence
  • UP000036812 Componenti: Unassembled WGS sequence
  • UP000239654 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

CytoplasmUniRule annotation

Interactioni

Protein-protein interaction databases

STRINGi469008.ECD_00764

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 29Q_MOTIFInterPro annotationAdd BLAST29
Domaini32 – 208Helicase ATP-bindingInterPro annotationAdd BLAST177
Domaini219 – 381Helicase C-terminalInterPro annotationAdd BLAST163

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Motifi1 – 29Q motifPROSITE-ProRule annotationAdd BLAST29

Sequence similaritiesi

Belongs to the DEAD box helicase family. RhlE subfamily.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105C1J Bacteria
COG0513 LUCA

Family and domain databases

CDDicd00079 HELICc, 1 hit
HAMAPiMF_00968 DEAD_helicase_RhlE, 1 hit
InterProiView protein in InterPro
IPR011545 DEAD/DEAH_box_helicase_dom
IPR028622 DEAD_helicase_RhlE
IPR014001 Helicase_ATP-bd
IPR001650 Helicase_C
IPR027417 P-loop_NTPase
IPR000629 RNA-helicase_DEAD-box_CS
IPR014014 RNA_helicase_DEAD_Q_motif
PfamiView protein in Pfam
PF00270 DEAD, 1 hit
PF00271 Helicase_C, 1 hit
SMARTiView protein in SMART
SM00487 DEXDc, 1 hit
SM00490 HELICc, 1 hit
SUPFAMiSSF52540 SSF52540, 1 hit
PROSITEiView protein in PROSITE
PS00039 DEAD_ATP_HELICASE, 1 hit
PS51192 HELICASE_ATP_BIND_1, 1 hit
PS51194 HELICASE_CTER, 1 hit
PS51195 Q_MOTIF, 1 hit

Sequencei

Sequence statusi: Complete.

J7QYZ2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSFDSLGLSP DILRAVAEQG YREPTPIQQQ AIPAVLEGRD LMASAQTGTG
60 70 80 90 100
KTAGFTLPLL QHLITRQPHA KGRRPVRALI LTPTRELAAQ IGENVRDYSK
110 120 130 140 150
YLNIRSLVVF GGVSINPQMM KLRGGVDVLV ATPGRLLDLE HQNAVKLDQV
160 170 180 190 200
EILVLDEADR MLDMGFIHDI RRVLTKLPAK RQNLLFSATF SDDIKALAEK
210 220 230 240 250
LLHNPLEIEV ARRNTASDQV TQHVHFVDKK RKRELLSHMI GKGNWQQVLV
260 270 280 290 300
FTRTKHGANH LAEQLNKDGI RSAAIHGNKS QGARTRALAD FKSGDIRVLV
310 320 330 340 350
ATDIAARGLD IEELPHVVNY ELPNVPEDYV HRIGRTGRAA ATGEALSLVC
360 370 380 390 400
VDEHKLLRDI EKLLKKEIPR IAIPGYEPDP SIKAEPIQNG RQQRGGGGRG
410 420 430 440 450
QGGGRGQQQP RRGEGGAKSA SAKPAEKPSR RLGDAKPAGE QQRRRRPRKP

AAAQ
Length:454
Mass (Da):49,989
Last modified:October 31, 2012 - v1
Checksum:i7576B35B7901671F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP009106 Genomic DNA Translation: AIZ86329.1
CP010315 Genomic DNA Translation: AJE55103.1
CP007491 Genomic DNA Translation: ALY12287.1
CP010122 Genomic DNA Translation: APJ74878.1
CP017631 Genomic DNA Translation: APT03747.1
CP021175 Genomic DNA Translation: ARR36097.1
CP024821 Genomic DNA Translation: ATX08477.1
CP024141 Genomic DNA Translation: AUK02047.1
CP024127 Genomic DNA Translation: AUK22843.1
CP019051 Genomic DNA Translation: AUL71045.1
CP024056 Genomic DNA Translation: AUL86167.1
CP026202 Genomic DNA Translation: AUV30378.1
CP027205 Genomic DNA Translation: AVN02045.1
HE964769 Genomic DNA Translation: CCJ43277.1
HG976952 Genomic DNA Translation: CDU39451.1
CXZU01000030 Genomic DNA Translation: CTS22940.1
CYAQ01000011 Genomic DNA Translation: CTS42307.1
CYCX01000040 Genomic DNA Translation: CTW66179.1
CYDH01000051 Genomic DNA Translation: CTW69726.1
CYFX01000001 Genomic DNA Translation: CTY93382.1
JPKH01000044 Genomic DNA Translation: KGM68226.1
JPKL01000104 Genomic DNA Translation: KGM78127.1
JPMZ01000049 Genomic DNA Translation: KGM80477.1
LEUM01000005 Genomic DNA Translation: KLY03055.1
LGZP01000047 Genomic DNA Translation: KNF76384.1
LDYI01000046 Genomic DNA Translation: KPO15962.1
LIVE01000045 Genomic DNA Translation: KQJ12801.1
LOOZ01000022 Genomic DNA Translation: KXR89854.1
LCVH01000013 Genomic DNA Translation: OAC44871.1
LZEH01000285 Genomic DNA Translation: OEI57264.1
MSEK01000090 Genomic DNA Translation: OLR86796.1
MTKH01000016 Genomic DNA Translation: ONG31570.1
MPAF01000026 Genomic DNA Translation: OOK27032.1
NAHY01000128 Genomic DNA Translation: ORJ77903.1
NAFT01000024 Genomic DNA Translation: ORT07610.1
NBCM01000015 Genomic DNA Translation: OTE92868.1
MUAB01000019 Genomic DNA Translation: OUK51547.1
LYBG01000563 Genomic DNA Translation: OWD71379.1
LEOO01000013 Genomic DNA Translation: OYC69087.1
PDEE01000004 Genomic DNA Translation: PEH98601.1
PITP01000005 Genomic DNA Translation: PKD90866.1
JWSO02000007 Genomic DNA Translation: PNP05864.1
LT883142 Genomic DNA Translation: SMZ46178.1
RefSeqiWP_000007101.1, NZ_PUEB01000011.1

Genome annotation databases

EnsemblBacteriaiAJE55103; AJE55103; AC789_1c08310
ALY12287; ALY12287; ACN002_0829
ALZ69093; ALZ69093; AWH59_24425
ANM81537; ANM81537; A8V37_03080
AOT33632; AOT33632; FORC31_3175
CDU39451; CDU39451; PGD_02537
CTS22940; CTS22940; ERS085374_03879
CTS42307; CTS42307; ERS085365_01677
CTW66179; CTW66179; ERS085416_03983
CTW69726; CTW69726; ERS139211_03961
CTX30705; CTX30705; ERS139235_01836
CTY84431; CTY84431; ERS139269_03727
CTY93382; CTY93382; ERS150873_00286
KGM68226; KGM68226; EL75_2997
KGM78127; KGM78127; EL80_3048
KGM80477; KGM80477; EL79_3087
KIG79099; KIG79099; PU38_19055
KIQ48076; KIQ48076; IY32_01980
KLG78941; KLG78941; WR12_06340
KLY03055; KLY03055; SK85_00799
KNF76384; KNF76384; WQ89_21215
KPO15962; KPO15962; ACU57_05775
KQJ12801; KQJ12801; AM266_20870
KXQ42027; KXQ42027; AUQ01_04185
OAC44871; OAC44871; EC3234A_13c00160
OCO54646; OCO54646; AN669_0214430
ODA89040; ODA89040; A9D65_00725
ODH32637; ODH32637; A6803_04120
OEI57264; OEI57264; A9R57_22115
PATRICifig|562.10472.peg.428

Similar proteinsi

Entry informationi

Entry nameiJ7QYZ2_ECOLX
AccessioniPrimary (citable) accession number: J7QYZ2
Entry historyiIntegrated into UniProtKB/TrEMBL: October 31, 2012
Last sequence update: October 31, 2012
Last modified: June 20, 2018
This is version 60 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

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