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Protein

Phosphoenolpyruvate carboxylase

Gene

ppc

Organism
Methylocystis sp. (strain SC2)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.UniRule annotation

Catalytic activityi

Phosphate + oxaloacetate = H2O + phosphoenolpyruvate + HCO3-.UniRule annotationSAAS annotation

Cofactori

Mg2+UniRule annotationSAAS annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei166 – 1661UniRule annotation
Active sitei598 – 5981UniRule annotation

GO - Molecular functioni

  1. magnesium ion binding Source: UniProtKB-HAMAP
  2. phosphoenolpyruvate carboxylase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. carbon fixation Source: UniProtKB-HAMAP
  2. oxaloacetate metabolic process Source: UniProtKB-HAMAP
  3. tricarboxylic acid cycle Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

LyaseUniRule annotationSAAS annotation

Keywords - Biological processi

Carbon dioxide fixationUniRule annotationSAAS annotation

Keywords - Ligandi

MagnesiumUniRule annotationSAAS annotation, PyruvateImported

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoenolpyruvate carboxylaseUniRule annotationSAAS annotation (EC:4.1.1.31UniRule annotationSAAS annotation)
Short name:
PEPCUniRule annotation
Short name:
PEPCaseUniRule annotation
Gene namesi
Name:ppcUniRule annotationImported
Ordered Locus Names:BN69_1789Imported
OrganismiMethylocystis sp. (strain SC2)Imported
Taxonomic identifieri187303 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesMethylocystaceaeMethylocystis
ProteomesiUP000005263 Componenti: Chromosome

Interactioni

Subunit structurei

Homotetramer.UniRule annotation

Family & Domainsi

Sequence similaritiesi

Belongs to the PEPCase type 1 family.UniRule annotation

Phylogenomic databases

KOiK01595.

Family and domain databases

HAMAPiMF_00595. PEPcase_type1.
InterProiIPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view]
PfamiPF00311. PEPcase. 1 hit.
[Graphical view]
PRINTSiPR00150. PEPCARBXLASE.
SUPFAMiSSF51621. SSF51621. 1 hit.
PROSITEiPS00781. PEPCASE_1. 1 hit.
PS00393. PEPCASE_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

J7QT34-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MQLEAQAQEN LVTAAPPAGA DPEALKGDES LIEDIRLLGR LLGDAVREHE
60 70 80 90 100
GSAAFERIET IRRLSVAASR NGDAEADRNL DALLRSLTAE EARTVIRAFS
110 120 130 140 150
YFSHLANIAE DLHPLQQRAR AQASGAFTGA PSLATTFARL RKAAVGAGRI
160 170 180 190 200
AQALARGWIS PVLTAHPTEV RRKSLLDAEH AIFKLLAARE HMRGKAERAQ
210 220 230 240 250
NEMQLRARVS QLWQTELLRH SRLTVRDEIE NTLSYYRSTF LREIPRLYAD
260 270 280 290 300
IEQRLDGLRV PPFLRMGAWV GGDRDGNPNV TAESLSTALR MQCETVLRFY
310 320 330 340 350
LIEVHELGAE LSISRRYAGC TKALEALAAR SGDDNPHRDD EPYRRALIGV
360 370 380 390 400
YSRLAGTLEK LTGGQAARHA VAPGAPYANS WALLADLVTI DASLRVHHSE
410 420 430 440 450
VIATQRLEPL IRAVEVFGFH LATLDLRQSS DRHEETIAEL LNVARVVDDY
460 470 480 490 500
VALPEAEKQA LLLRLLSDPR PVRLPGATYS DRATSELTIM ERAREMRRLY
510 520 530 540 550
GDEAIRHYII SHTETVSDLL EVLLLQKECG LMRGTLDPRD AQRVIADLII
560 570 580 590 600
VPLFETIDDL RNAAPIMQEF YALPGVLKLV VNSGGQQDVM LGYSDSNKDG
610 620 630 640 650
GILTSIWELY RASTALAEFF ASAPNVTLRL FHGRGGTVGR GGGPSYDAIL
660 670 680 690 700
AQPPGTVNGQ IRLTEQGEVI AAKYANPQIG HVNLELLVAA TLEATLLSAH
710 720 730 740 750
KTPAPEFLEA AEELSQAGMA AYRGLVYGTE GFVDFFFSST PISEIASLNI
760 770 780 790 800
GSRPASRKPS RRIEDLRAIP WSFSWAQARV ALPGWYGFGS AIAHFIAEDE
810 820 830 840 850
KARLALLRRM SEEWPFFRAL LSNIDMILSK TDMSIAHHYA GLVEDKALAA
860 870 880 890 900
RIFGMIEAEH ARANDALEKL LGSKERLADN PTLARSIRHR FPYIAPLNYL
910 920 930
QVELIRRHRA GERGEDIREG ILMSINGVAA GLRNTG
Length:936
Mass (Da):103,335
Last modified:October 30, 2012 - v1
Checksum:i6961B4A74C8D25DA
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
HE956757 Genomic DNA. Translation: CCJ07240.1.
RefSeqiWP_014891269.1. NC_018485.1.
YP_006591891.1. NC_018485.1.

Genome annotation databases

EnsemblBacteriaiCCJ07240; CCJ07240; BN69_1789.
KEGGimsc:BN69_1789.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
HE956757 Genomic DNA. Translation: CCJ07240.1.
RefSeqiWP_014891269.1. NC_018485.1.
YP_006591891.1. NC_018485.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiCCJ07240; CCJ07240; BN69_1789.
KEGGimsc:BN69_1789.

Phylogenomic databases

KOiK01595.

Family and domain databases

HAMAPiMF_00595. PEPcase_type1.
InterProiIPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view]
PfamiPF00311. PEPcase. 1 hit.
[Graphical view]
PRINTSiPR00150. PEPCARBXLASE.
SUPFAMiSSF51621. SSF51621. 1 hit.
PROSITEiPS00781. PEPCASE_1. 1 hit.
PS00393. PEPCASE_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Complete genome sequence of Methylocystis sp. strain SC2, an aerobic methanotroph with high-affinity methane oxidation potential."
    Dam B., Dam S., Kube M., Reinhardt R., Liesack W.
    J. Bacteriol. 194:6008-6009(2011) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: SC2Imported.

Entry informationi

Entry nameiJ7QT34_METSZ
AccessioniPrimary (citable) accession number: J7QT34
Entry historyi
Integrated into UniProtKB/TrEMBL: October 30, 2012
Last sequence update: October 30, 2012
Last modified: March 31, 2015
This is version 18 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.