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Protein

Phosphoenolpyruvate carboxylase

Gene

ppc

Organism
Methylocystis sp. (strain SC2)
Status
Unreviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.UniRule annotationSAAS annotation

Catalytic activityi

Phosphate + oxaloacetate = H2O + phosphoenolpyruvate + HCO3-.UniRule annotationSAAS annotation

Cofactori

Mg2+UniRule annotationSAAS annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei140UniRule annotation1
Active sitei575UniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionLyaseUniRule annotationSAAS annotationImported
Biological processCarbon dioxide fixationUniRule annotationSAAS annotation
LigandMagnesiumUniRule annotationSAAS annotation, PyruvateImported

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoenolpyruvate carboxylaseUniRule annotationSAAS annotation (EC:4.1.1.31UniRule annotationSAAS annotation)
Short name:
PEPCUniRule annotation
Short name:
PEPCaseUniRule annotation
Gene namesi
Name:ppcUniRule annotationImported
Ordered Locus Names:BN69_1172Imported
OrganismiMethylocystis sp. (strain SC2)Imported
Taxonomic identifieri187303 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesMethylocystaceaeMethylocystis
Proteomesi
  • UP000005263 Componenti: Chromosome

Interactioni

Subunit structurei

Homotetramer.UniRule annotation

Family & Domainsi

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili872 – 896Sequence analysisAdd BLAST25

Sequence similaritiesi

Belongs to the PEPCase type 1 family.UniRule annotationSAAS annotation

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

KOiK01595.
OMAiGPTHRFI.
OrthoDBiPOG091H040O.

Family and domain databases

HAMAPiMF_00595. PEPcase_type1. 1 hit.
InterProiView protein in InterPro
IPR021135. PEP_COase.
IPR022805. PEP_COase_bac/pln-type.
IPR033129. PEPCASE_His_AS.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
PfamiView protein in Pfam
PF00311. PEPcase. 1 hit.
PRINTSiPR00150. PEPCARBXLASE.
SUPFAMiSSF51621. SSF51621. 1 hit.
PROSITEiView protein in PROSITE
PS00393. PEPCASE_2. 1 hit.

Sequencei

Sequence statusi: Complete.

J7QMX1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTAETQTLKS LSSTGLPSAY ATRSVTEASN FLREQLLTVI RRHTPEIEAV
60 70 80 90 100
VRDSKAGAGL EPRQMARALQ AQGILFQLVS IAEQAYAMRR RRRIEREKGH
110 120 130 140 150
DKLLGTFDYV LSSAAASGVA PDEIRAQLHT LRIRPVITAH PTEAKRVSIL
160 170 180 190 200
EKYRRIYLLM RELESTRWTD REREALVKSI YDQIELLWLT GELHLEKPTV
210 220 230 240 250
DQEVAWGQHF FHESIFDLAP ELLSSCERAL RRHYPNETFE VAPFFQFGSW
260 270 280 290 300
IGGDRDGNPF VTNDVTRRTM RENAAASLNY YRTRFVDLAR MLSISQRAAD
310 320 330 340 350
IPQSFREELA ERLATLPDGA AIEARNQNEP YRQFVMTILR KLDQTLRAVN
360 370 380 390 400
AEATTGPRYA SADELIADLL MLEKALTEAK SDAIATDLVR PLRRAVETFR
410 420 430 440 450
FSTVRLDIRQ NTTRTTQALE ELWRLKTGGE TPPDLDAPEW RQWLLAELAK
460 470 480 490 500
PRQTPLPRDR LSADTRDVIE MFEVVAEMRT QLDREAFGGF ILSMTRSAVD
510 520 530 540 550
VLGVYLLAKE AGLFLDEPGV EILTLPIVPL FETIGDLRAA PAIMRDLLQV
560 570 580 590 600
PVVRRSTRWQ GNLQEVMIGY SDSNKDGGFL SSNWELFKAQ ARLTQVGREQ
610 620 630 640 650
GVAIAFFHGR GGSVSRGGAP TGHAIAAQPA GSIRGRFRVT EQGEVVSFKY
660 670 680 690 700
ANRGTAAYQM ELLASSVFQH ALKSEREEAL APHAEFDEAL EEISGASFAA
710 720 730 740 750
YAKFIGDPDL VAYFQAASPL EEISLLNIGS RPARRFGAKS LADLRAIPWV
760 770 780 790 800
FAWAQNRHAI TGWYGVGSGL KNFVDVRGDR GFELLRRMFE DSRMFRLIID
810 820 830 840 850
EVEKTLALVD LSIAKQYAGL VADEAVRNKI FKAIEEEFAL TREMALRVTG
860 870 880 890 900
GVELAERFKE YQARLSHRLQ TINEVNREQV ALLRRFREAK DEAEKEAVKV
910
PLLLSISCVA AGLGATG
Length:917
Mass (Da):103,072
Last modified:October 31, 2012 - v1
Checksum:i8A50B453A370B649
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
HE956757 Genomic DNA. Translation: CCJ06623.1.
RefSeqiWP_014890656.1. NC_018485.1.

Genome annotation databases

EnsemblBacteriaiCCJ06623; CCJ06623; BN69_1172.
KEGGimsc:BN69_1172.
PATRICifig|187303.17.peg.1279.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Entry informationi

Entry nameiJ7QMX1_METSZ
AccessioniPrimary (citable) accession number: J7QMX1
Entry historyiIntegrated into UniProtKB/TrEMBL: October 31, 2012
Last sequence update: October 31, 2012
Last modified: June 7, 2017
This is version 35 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported