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Protein

Glutamate decarboxylase

Gene

gadG

Organism
Listeria monocytogenes ATCC 19117
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

L-glutamate = 4-aminobutanoate + CO2.UniRule annotation

Cofactori

pyridoxal 5'-phosphateUniRule annotation

GO - Molecular functioni

  1. glutamate decarboxylase activity Source: UniProtKB-EC
  2. pyridoxal phosphate binding Source: InterPro

GO - Biological processi

  1. glutamate metabolic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

DecarboxylaseUniRule annotation, Lyase

Keywords - Ligandi

Pyridoxal phosphateUniRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Glutamate decarboxylaseUniRule annotation (EC:4.1.1.15UniRule annotation)
Gene namesi
Name:gadGImported
ORF Names:LMOATCC19117_2362Imported
OrganismiListeria monocytogenes ATCC 19117Imported
Taxonomic identifieri882095 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesListeriaceaeListeria
ProteomesiUP000004013: Chromosome

Family & Domainsi

Sequence similaritiesi

Belongs to the group II decarboxylase family.UniRule annotation

Phylogenomic databases

KOiK01580.

Family and domain databases

Gene3Di3.40.640.10. 1 hit.
InterProiIPR010107. Glutamate_decarboxylase.
IPR002129. PyrdxlP-dep_de-COase.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
[Graphical view]
PANTHERiPTHR11999:SF1. PTHR11999:SF1. 1 hit.
PfamiPF00282. Pyridoxal_deC. 1 hit.
[Graphical view]
SUPFAMiSSF53383. SSF53383. 1 hit.
TIGRFAMsiTIGR01788. Glu-decarb-GAD. 1 hit.

Sequencei

Sequence statusi: Complete.

J7PRZ0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLYSKENKES YLEPVFGSSA EDRDIPKYTL GKEPLEPRIA YRLVKDELLD
60 70 80 90 100
EGSARQNLAT FCQTYMEDEA TKLMSETLEK NAIDKSEYPR TAELENRCVN
110 120 130 140 150
IIADLWHAPK DQKFMGTSTI GSSEACMLGG MAMKFAWRKR AEKLGLDIYA
160 170 180 190 200
QKPNLVISSG YQVCWEKFCV YWDIDMRVVP MDKDHMQLNT DQVLDYVDEY
210 220 230 240 250
TIGVVGILGI TYTGRYDDIY ALNEKLEEYN SKTDYKVYIH VDAASGGFFT
260 270 280 290 300
PFVEPDIIWD FRLKNVISIN TSGHKYGLVY PGIGWVLWKD ESYLPEELIF
310 320 330 340 350
KVSYLGGEMP TMQINFSRSA SHIIGQYYNF LRYGFEGYRT IHQKTSDVAQ
360 370 380 390 400
YLAHAVEQTG YFDIYNDGSH LPIVCYKLKD DANVKWTLYD LADRLQMRGW
410 420 430 440 450
QVPAYPLPKN LENIIIQRYV CRADLGFNMA EEFIQDFQAS IQELNNAHIL
460
FHDTQQSGVH GFTH
Length:464
Mass (Da):53,586
Last modified:October 31, 2012 - v1
Checksum:iF194FDC8566D96DF
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
FR733643 Genomic DNA. Translation: CBY71261.1.
RefSeqiYP_006674163.1. NC_018584.1.

Genome annotation databases

EnsemblBacteriaiCBY71261; CBY71261; LMOATCC19117_2362.
GeneIDi13641528.
KEGGilmoa:LMOATCC19117_2362.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
FR733643 Genomic DNA. Translation: CBY71261.1.
RefSeqiYP_006674163.1. NC_018584.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiCBY71261; CBY71261; LMOATCC19117_2362.
GeneIDi13641528.
KEGGilmoa:LMOATCC19117_2362.

Phylogenomic databases

KOiK01580.

Family and domain databases

Gene3Di3.40.640.10. 1 hit.
InterProiIPR010107. Glutamate_decarboxylase.
IPR002129. PyrdxlP-dep_de-COase.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
[Graphical view]
PANTHERiPTHR11999:SF1. PTHR11999:SF1. 1 hit.
PfamiPF00282. Pyridoxal_deC. 1 hit.
[Graphical view]
SUPFAMiSSF53383. SSF53383. 1 hit.
TIGRFAMsiTIGR01788. Glu-decarb-GAD. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. "Reassessment of the Listeria monocytogenes pan-genome reveals dynamic integration hotspots and mobile genetic elements as major components of the accessory genome."
    Kuenne C., Billion A., Mraheil M.A., Strittmatter A., Daniel R., Goesmann A., Barbuddhe S., Hain T., Chakraborty T.
    BMC Genomics 14:47-47(2013) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 19117Imported.

Entry informationi

Entry nameiJ7PRZ0_LISMN
AccessioniPrimary (citable) accession number: J7PRZ0
Entry historyi
Integrated into UniProtKB/TrEMBL: October 31, 2012
Last sequence update: October 31, 2012
Last modified: February 4, 2015
This is version 14 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.