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J7PMU5 (J7PMU5_LISMN) Unreviewed, UniProtKB/TrEMBL

Last modified February 19, 2014. Version 13. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein namesRecommended name:
Alanine racemase HAMAP-Rule MF_01201 RuleBase RU004247

EC=5.1.1.1 HAMAP-Rule MF_01201 RuleBase RU004247
Gene names
Name:alr EMBL CBY69804.1
ORF Names:LMOATCC19117_0905 EMBL CBY69804.1
OrganismListeria monocytogenes ATCC 19117 [Complete proteome] EMBL CBY69804.1
Taxonomic identifier882095 [NCBI]
Taxonomic lineageBacteriaFirmicutesBacilliBacillalesListeriaceaeListeria

Protein attributes

Sequence length368 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids By similarity. HAMAP-Rule MF_01201

Catalytic activity

L-alanine = D-alanine. HAMAP-Rule MF_01201 RuleBase RU004247 SAAS SAAS009006

Cofactor

Pyridoxal phosphate By similarity. HAMAP-Rule MF_01201 SAAS SAAS009006

Pathway

Amino-acid biosynthesis; D-alanine biosynthesis; D-alanine from L-alanine: step 1/1. HAMAP-Rule MF_01201

Sequence similarities

Belongs to the alanine racemase family. HAMAP-Rule MF_01201 RuleBase RU004188

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Active site401Proton acceptor; specific for D-alanine By similarity HAMAP-Rule MF_01201
Active site2631Proton acceptor; specific for L-alanine By similarity HAMAP-Rule MF_01201
Binding site1341Substrate By similarity HAMAP-Rule MF_01201
Binding site3101Substrate; via amide nitrogen By similarity HAMAP-Rule MF_01201

Amino acid modifications

Modified residue401N6-(pyridoxal phosphate)lysine By similarity HAMAP-Rule MF_01201

Sequences

Sequence LengthMass (Da)Tools
J7PMU5 [UniParc].

Last modified October 31, 2012. Version 1.
Checksum: FA192B48C2D9BC3B

FASTA36841,054
        10         20         30         40         50         60 
MVTGWHRPTW IEIDRAAIRE NIKNEQNKLP ENVDLWAVVK ANAYGHGIIE VARTAKEAGA 

        70         80         90        100        110        120 
KGFCVAILDE ALALREAGFQ DDFILVLGAT RKEDANLAAK NHISLTVFRE DWLEDLTLEA 

       130        140        150        160        170        180 
PLRIHLKVDS GMGRLGIRTT DEARRIETTI AKDNQLQLEG IYTHFATADQ LETSYFEQQL 

       190        200        210        220        230        240 
AKFQTILTSL KNRPTYVHTA NSAASLLQPQ IGFDAIRFGI SMYGLTPSTE IKTSLPFELK 

       250        260        270        280        290        300 
PALALYTEMV HVKELAPGDS VSYGATYTAT EREWVATLPI GYADGLIRHY SGFHVLVDGE 

       310        320        330        340        350        360 
LAPIIGRVCM DQTIIKLPRE FQTGSKVTII GTDHGNTITA DDAAHYLDTI NYEVTCLLNE 


RIPRKYIH 

« Hide

References

[1]"Reassessment of the Listeria monocytogenes pan-genome reveals dynamic integration hotspots and mobile genetic elements as major components of the accessory genome."
Kuenne C., Billion A., Mraheil M.A., Strittmatter A., Daniel R., Goesmann A., Barbuddhe S., Hain T., Chakraborty T.
BMC Genomics 14:47-47(2013) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE.
Strain: ATCC 19117 EMBL CBY69804.1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
FR733643 Genomic DNA. Translation: CBY69804.1.
RefSeqYP_006672706.1. NC_018584.1.

3D structure databases

ProteinModelPortalJ7PMU5.
SMRJ7PMU5. Positions 4-367.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaCBY69804; CBY69804; LMOATCC19117_0905.
GeneID13641217.
KEGGlmoa:LMOATCC19117_0905.

Organism-specific databases

CMRSearch...

Phylogenomic databases

KOK01775.

Enzyme and pathway databases

UniPathwayUPA00042; UER00497.

Family and domain databases

Gene3D2.40.37.10. 1 hit.
HAMAPMF_01201. Ala_racemase.
InterProIPR000821. Ala_racemase.
IPR009006. Ala_racemase/Decarboxylase_C.
IPR011079. Ala_racemase_C.
IPR001608. Ala_racemase_N.
IPR020622. Ala_racemase_pyridoxalP-BS.
[Graphical view]
PfamPF00842. Ala_racemase_C. 1 hit.
PF01168. Ala_racemase_N. 1 hit.
[Graphical view]
PRINTSPR00992. ALARACEMASE.
SMARTSM01005. Ala_racemase_C. 1 hit.
[Graphical view]
SUPFAMSSF50621. SSF50621. 1 hit.
TIGRFAMsTIGR00492. alr. 1 hit.
PROSITEPS00395. ALANINE_RACEMASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameJ7PMU5_LISMN
AccessionPrimary (citable) accession number: J7PMU5
Entry history
Integrated into UniProtKB/TrEMBL: October 31, 2012
Last sequence update: October 31, 2012
Last modified: February 19, 2014
This is version 13 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)