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Protein

Glutamate decarboxylase

Gene

B005_2430

Organism
Nocardiopsis alba (strain ATCC BAA-2165 / BE74)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

L-glutamate = 4-aminobutanoate + CO2.UniRule annotation

Cofactori

pyridoxal 5'-phosphateUniRule annotation

GO - Molecular functioni

  1. glutamate decarboxylase activity Source: UniProtKB-EC
  2. pyridoxal phosphate binding Source: InterPro

GO - Biological processi

  1. glutamate metabolic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

DecarboxylaseUniRule annotation, Lyase

Keywords - Ligandi

Pyridoxal phosphateUniRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Glutamate decarboxylaseUniRule annotation (EC:4.1.1.15UniRule annotation)
Gene namesi
Ordered Locus Names:B005_2430Imported
OrganismiNocardiopsis alba (strain ATCC BAA-2165 / BE74)Imported
Taxonomic identifieri1205910 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeActinomycetalesStreptosporangineaeNocardiopsaceaeNocardiopsis
ProteomesiUP000003779: Chromosome

Family & Domainsi

Sequence similaritiesi

Belongs to the group II decarboxylase family.UniRule annotation

Phylogenomic databases

KOiK01580.
OMAiDPDLVWD.

Family and domain databases

Gene3Di3.40.640.10. 1 hit.
InterProiIPR010107. Glutamate_decarboxylase.
IPR002129. PyrdxlP-dep_de-COase.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
[Graphical view]
PANTHERiPTHR11999:SF1. PTHR11999:SF1. 1 hit.
PfamiPF00282. Pyridoxal_deC. 1 hit.
[Graphical view]
SUPFAMiSSF53383. SSF53383. 1 hit.
TIGRFAMsiTIGR01788. Glu-decarb-GAD. 1 hit.

Sequencei

Sequence statusi: Complete.

J7L0N0-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MRAPDPDEDV YAERLMRRGA PKGDFPERGT EARVAYQLVH DELMLDGISR
60 70 80 90 100
MNLATFCTTW VEPEVRMLMD ESIDKNMIDK DEYPQTAELE RRCVRMLADL
110 120 130 140 150
WHVPEPSDPV GISTTGSSEA AMLAGLAAKF SWRARREAEG RPTDRPNLVC
160 170 180 190 200
GPVQVCWEKF ALYFDVELRR IPLSGDTYVM TPDDVDRYCD ENTIMVVCNF
210 220 230 240 250
AQTFTGLFED VSGVAAALDR FEERTGHDIP LHVDGASGAF TAPFVSPDLV
260 270 280 290 300
WDFRLPRVRS INASGHKTGL APLGSGWAMW RRKADLPEEL VFQVDYLGGN
310 320 330 340 350
QATFNLNFSR PGGQVVTQYY DFVRLGREGY RMIHSATHET ARHLAEGVRA
360 370 380 390 400
MGPFDLVHDG HPDRGIGAVS WRLVGDEPFT PYDLADRLRT RGWLVPAYPL
410 420 430 440 450
PADRDSEAVQ RVLVRHGFSR DMSDLLLEDI ESAIEHLRTH PPSVPLGRDE
460 470
AGGFNHGARS VIDRADVPSP RPARESRR
Length:478
Mass (Da):53,706
Last modified:October 31, 2012 - v1
Checksum:iBAE354F169428DDF
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP003788 Genomic DNA. Translation: AFR07193.1.
RefSeqiWP_014909657.1. NC_018524.1.
YP_006641523.1. NC_018524.1.

Genome annotation databases

EnsemblBacteriaiAFR07193; AFR07193; B005_2430.
GeneIDi13546772.
KEGGinal:B005_2430.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP003788 Genomic DNA. Translation: AFR07193.1.
RefSeqiWP_014909657.1. NC_018524.1.
YP_006641523.1. NC_018524.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAFR07193; AFR07193; B005_2430.
GeneIDi13546772.
KEGGinal:B005_2430.

Phylogenomic databases

KOiK01580.
OMAiDPDLVWD.

Family and domain databases

Gene3Di3.40.640.10. 1 hit.
InterProiIPR010107. Glutamate_decarboxylase.
IPR002129. PyrdxlP-dep_de-COase.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
[Graphical view]
PANTHERiPTHR11999:SF1. PTHR11999:SF1. 1 hit.
PfamiPF00282. Pyridoxal_deC. 1 hit.
[Graphical view]
SUPFAMiSSF53383. SSF53383. 1 hit.
TIGRFAMsiTIGR01788. Glu-decarb-GAD. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. "Whole-genome sequence of Nocardiopsis alba strain ATCC BAA-2165 associated with honeybees."
    Qiao J., Chen L., Li Y., Wang J., Zhang W., Chen S.
    Submitted (AUG-2012) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC BAA-2165 / BE74Imported.

Entry informationi

Entry nameiJ7L0N0_NOCAA
AccessioniPrimary (citable) accession number: J7L0N0
Entry historyi
Integrated into UniProtKB/TrEMBL: October 31, 2012
Last sequence update: October 31, 2012
Last modified: February 4, 2015
This is version 14 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.