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J7KMQ4 (J7KMQ4_STRSU) Unreviewed, UniProtKB/TrEMBL

Last modified January 22, 2014. Version 8. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Isocitrate dehydrogenase [NADP] RuleBase RU004446

EC=1.1.1.42 RuleBase RU004446
Gene names
ORF Names:YYK_04955 EMBL AFR00510.1
OrganismStreptococcus suis S735 [Complete proteome] EMBL AFR00510.1
Taxonomic identifier1184252 [NCBI]
Taxonomic lineageBacteriaFirmicutesBacilliLactobacillalesStreptococcaceaeStreptococcus

Protein attributes

Sequence length393 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

Isocitrate + NADP+ = 2-oxoglutarate + CO2 + NADPH. RuleBase RU004446

Cofactor

Binds 1 magnesium or manganese ion per subunit By similarity. RuleBase RU004446

Sequence similarities

Belongs to the isocitrate and isopropylmalate dehydrogenases family. RuleBase RU004443

Sequences

Sequence LengthMass (Da)Tools
J7KMQ4 [UniParc].

Last modified October 31, 2012. Version 1.
Checksum: 60138A369089D381

FASTA39343,247
        10         20         30         40         50         60 
MAEKILMREG RLIVPDCPVI PYIEGDGIGR DIWSVSQKVI DAAVKKAYAG QRSIQWREVF 

        70         80         90        100        110        120 
AGEKAYELMG TSLPNETLEI IREHLVAIKG PLGTPIGKGH RSLNVALRQE LDLYACVRPI 

       130        140        150        160        170        180 
RYFKGVPSPL KEPEKTDITI FRENTEDIYA GIEWEAGSDE VAKVISFLQE EMGVVNIRFP 

       190        200        210        220        230        240 
ESSSIGIKPI SEEGSKRLIR SAIEYALEHQ LKMVTLVHKG NIQKFTEGGF RKWGYELAKE 

       250        260        270        280        290        300 
EFATELAEGT LVVNDIIADN FLQQILLAPE NFQVVALTNL NGDYASDALA AQVGGIGISP 

       310        320        330        340        350        360 
GANINYQTGH AIFEATHGTA PDIAGKDLAN PCSLLLSACM MLEYIGWKEA AVLIIQALED 

       370        380        390 
AFINKNVTLD FAKILDVAHQ STSQFSEVLI DSI 

« Hide

References

[1]"Genome Sequence of the Swine Pathogen Streptococcus suis Serotype 2 Strain S735."
Boyle B., Vaillancourt K., Bonifait L., Charette S.J., Gottschalk M., Grenier D.
J. Bacteriol. 194:6343-6344(2012) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE.
Strain: S735 EMBL AFR00510.1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP003736 Genomic DNA. Translation: AFR00510.1.
RefSeqYP_006649908.1. NC_018526.1.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAFR00510; AFR00510; YYK_04955.
GeneID13537949.
KEGGsup:YYK_04955.

Organism-specific databases

CMRSearch...

Phylogenomic databases

KOK00031.

Family and domain databases

Gene3D3.40.718.10. 1 hit.
InterProIPR019818. IsoCit/isopropylmalate_DH_CS.
IPR001804. Isocitrate/isopropylmalate_DH.
IPR004439. Isocitrate_DH_NADP_dimer_prok.
IPR024084. IsoPropMal-DH-like_dom.
[Graphical view]
PANTHERPTHR11835. PTHR11835. 1 hit.
PfamPF00180. Iso_dh. 1 hit.
[Graphical view]
TIGRFAMsTIGR00183. prok_nadp_idh. 1 hit.
PROSITEPS00470. IDH_IMDH. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameJ7KMQ4_STRSU
AccessionPrimary (citable) accession number: J7KMQ4
Entry history
Integrated into UniProtKB/TrEMBL: October 31, 2012
Last sequence update: October 31, 2012
Last modified: January 22, 2014
This is version 8 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)