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J7J9L0

- J7J9L0_BURCE

UniProt

J7J9L0 - J7J9L0_BURCE

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Protein

Alanine racemase

Gene
GEM_4542
Organism
Burkholderia cepacia GG4
Status
Unreviewed - Annotation score: 2 out of 5 - Experimental evidence at protein leveli

Functioni

Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids By similarity.UniRule annotation

Catalytic activityi

L-alanine = D-alanine.UniRule annotationSAAS annotations

Cofactori

Pyridoxal phosphate By similarity.UniRule annotationSAAS annotations

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei35 – 351Proton acceptor; specific for D-alanine By similarityUniRule annotation
Binding sitei130 – 1301Substrate By similarityUniRule annotation
Active sitei252 – 2521Proton acceptor; specific for L-alanine By similarityUniRule annotation
Binding sitei300 – 3001Substrate; via amide nitrogen By similarityUniRule annotation

GO - Molecular functioni

  1. alanine racemase activity Source: UniProtKB-HAMAP
  2. pyridoxal phosphate binding Source: UniProtKB-HAMAP

GO - Biological processi

  1. D-alanine biosynthetic process Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

IsomeraseUniRule annotationSAAS annotationsImported

Keywords - Ligandi

Pyridoxal phosphateUniRule annotationSAAS annotations

Enzyme and pathway databases

UniPathwayiUPA00042; UER00497.

Names & Taxonomyi

Protein namesi
Recommended name:
Alanine racemaseUniRule annotation (EC:5.1.1.1UniRule annotation)
Gene namesi
ORF Names:GEM_4542Imported
OrganismiBurkholderia cepacia GG4Imported
Taxonomic identifieri1009846 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaBurkholderialesBurkholderiaceaeBurkholderiaBurkholderia cepacia complex

PTM / Processingi

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei35 – 351N6-(pyridoxal phosphate)lysine By similarityUniRule annotation

Structurei

3D structure databases

ProteinModelPortaliJ7J9L0.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

KOiK01775.

Family and domain databases

Gene3Di2.40.37.10. 1 hit.
3.20.20.10. 1 hit.
HAMAPiMF_01201. Ala_racemase.
InterProiIPR000821. Ala_racemase.
IPR009006. Ala_racemase/Decarboxylase_C.
IPR011079. Ala_racemase_C.
IPR001608. Ala_racemase_N.
IPR020622. Ala_racemase_pyridoxalP-BS.
IPR029066. PLP-binding_barrel.
[Graphical view]
PfamiPF00842. Ala_racemase_C. 1 hit.
PF01168. Ala_racemase_N. 1 hit.
[Graphical view]
PRINTSiPR00992. ALARACEMASE.
SMARTiSM01005. Ala_racemase_C. 1 hit.
[Graphical view]
SUPFAMiSSF50621. SSF50621. 1 hit.
SSF51419. SSF51419. 1 hit.
TIGRFAMsiTIGR00492. alr. 1 hit.
PROSITEiPS00395. ALANINE_RACEMASE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

J7J9L0-1 [UniParc]FASTAAdd to Basket

« Hide

MPRPIVAHIR PDAVRHNLDF IRRTAAQSRV WAVIKANAYG HGVERIYPGL    50
AAADGIALLD LDEAVRVREL GWDKPVLLLE GIFEPADVEL ADRHRLTVAV 100
HCDQQLDLLI AAKPQQPIDI QLKMNSGMNR LGYRPDAFRA AWERAAAAPS 150
IGKITLMMHF ANADEGEVDW QLEQFDATTA GIPGERSASN SAAVLWHPRA 200
HRDWVRPGTI LYGASPTGAA RHIADTPLMA AMTLTSKIIG VQTLAPEETV 250
GYGRRFTVDR PMRIGVVACG YADGYPRHAP TGTPIAVDGV MTRVVGRVSM 300
DMLTVDLTPC PNAGIGSSVE LWGDQVKVDD VAEASGTIGY ELMCALARRV 350
PVVIEPPGAS TLQPALRTGS YGR 373
Length:373
Mass (Da):40,354
Last modified:October 31, 2012 - v1
Checksum:iCB1342090FFC6DBD
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP003775 Genomic DNA. Translation: AFQ50932.1.
RefSeqiWP_014899697.1. NC_018514.1.
YP_006618626.1. NC_018514.1.

Genome annotation databases

EnsemblBacteriaiAFQ50932; AFQ50932; GEM_4542.
GeneIDi13509567.
KEGGibct:GEM_4542.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP003775 Genomic DNA. Translation: AFQ50932.1 .
RefSeqi WP_014899697.1. NC_018514.1.
YP_006618626.1. NC_018514.1.

3D structure databases

ProteinModelPortali J7J9L0.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AFQ50932 ; AFQ50932 ; GEM_4542 .
GeneIDi 13509567.
KEGGi bct:GEM_4542.

Phylogenomic databases

KOi K01775.

Enzyme and pathway databases

UniPathwayi UPA00042 ; UER00497 .

Family and domain databases

Gene3Di 2.40.37.10. 1 hit.
3.20.20.10. 1 hit.
HAMAPi MF_01201. Ala_racemase.
InterProi IPR000821. Ala_racemase.
IPR009006. Ala_racemase/Decarboxylase_C.
IPR011079. Ala_racemase_C.
IPR001608. Ala_racemase_N.
IPR020622. Ala_racemase_pyridoxalP-BS.
IPR029066. PLP-binding_barrel.
[Graphical view ]
Pfami PF00842. Ala_racemase_C. 1 hit.
PF01168. Ala_racemase_N. 1 hit.
[Graphical view ]
PRINTSi PR00992. ALARACEMASE.
SMARTi SM01005. Ala_racemase_C. 1 hit.
[Graphical view ]
SUPFAMi SSF50621. SSF50621. 1 hit.
SSF51419. SSF51419. 1 hit.
TIGRFAMsi TIGR00492. alr. 1 hit.
PROSITEi PS00395. ALANINE_RACEMASE. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Complete Genome Sequence of Burkholderia sp. Strain GG4, a Betaproteobacterium That Reduces 3-Oxo-N-Acylhomoserine Lactones and Produces Different N-Acylhomoserine Lactones."
    Hong K.W., Koh C.L., Sam C.K., Yin W.F., Chan K.G.
    J. Bacteriol. 194:6317-6317(2012) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: GG4Imported.

Entry informationi

Entry nameiJ7J9L0_BURCE
AccessioniPrimary (citable) accession number: J7J9L0
Entry historyi
Integrated into UniProtKB/TrEMBL: October 31, 2012
Last sequence update: October 31, 2012
Last modified: September 3, 2014
This is version 14 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

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