Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

J7GUU3

- J7GUU3_MYCGL

UniProt

J7GUU3 - J7GUU3_MYCGL

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

Thymidine kinase

Gene

tdk

Organism
Mycoplasma gallisepticum NC08_2008.031-4-3P
Status
Unreviewed - Annotation score: 3 out of 5- Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + thymidine = ADP + thymidine 5'-phosphate.UniRule annotationSAAS annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei94 – 941Proton acceptorUniRule annotation
Metal bindingi150 – 1501ZincUniRule annotation
Metal bindingi153 – 1531ZincUniRule annotation
Metal bindingi188 – 1881ZincUniRule annotation
Metal bindingi191 – 1911ZincUniRule annotation

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi19 – 268ATPUniRule annotation
Nucleotide bindingi93 – 964ATPUniRule annotation

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-HAMAP
  2. thymidine kinase activity Source: UniProtKB-HAMAP
  3. zinc ion binding Source: UniProtKB-HAMAP

GO - Biological processi

  1. DNA replication Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

KinaseUniRule annotation, Transferase

Keywords - Biological processi

DNA synthesisUniRule annotation

Keywords - Ligandi

ATP-bindingUniRule annotation, Metal-bindingUniRule annotationSAAS annotation, Nucleotide-binding, ZincUniRule annotationSAAS annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Thymidine kinaseUniRule annotation (EC:2.7.1.21UniRule annotation)
Gene namesi
Name:tdkUniRule annotationImported
ORF Names:HFMG08NCA_4952Imported
OrganismiMycoplasma gallisepticum NC08_2008.031-4-3PImported
Taxonomic identifieri1159204 [NCBI]
Taxonomic lineageiBacteriaTenericutesMollicutesMycoplasmataceaeMycoplasma
ProteomesiUP000003938: Chromosome

Subcellular locationi

Cytoplasm UniRule annotationSAAS annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

CytoplasmUniRule annotationSAAS annotation

Interactioni

Subunit structurei

Homotetramer.UniRule annotationSAAS annotation

Structurei

3D structure databases

ProteinModelPortaliJ7GUU3.
SMRiJ7GUU3. Positions 12-212.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the thymidine kinase family.UniRule annotation

Phylogenomic databases

KOiK00857.

Family and domain databases

HAMAPiMF_00124. Thymidine_kinase.
InterProiIPR027417. P-loop_NTPase.
IPR001267. Thymidine_kinase.
IPR020633. Thymidine_kinase_CS.
IPR020634. Thymidine_kinase_subgr.
[Graphical view]
PANTHERiPTHR11441. PTHR11441. 1 hit.
PfamiPF00265. TK. 1 hit.
[Graphical view]
PIRSFiPIRSF035805. TK_cell. 1 hit.
SUPFAMiSSF52540. SSF52540. 1 hit.
PROSITEiPS00603. TK_CELLULAR_TYPE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

J7GUU3-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MAKKNAMTTT NGWIEAICGP MFAGKTDELI RKIKRYEYAD VKSLVFSPAT
60 70 80 90 100
DTRSAQEIIN SRDGRRIGSI KIKKAFEIYD YVLLHKPQLV GIDEVQFFDD
110 120 130 140 150
SIVEVIQTLA DNQINVIVAG LDRDFRGEPF GPIPKILGIA ESVIRLTAIC
160 170 180 190 200
SECGAEASRS QRLIDNQPAD YNCETILIGD TESYAPRCRH HHKVPNRPIN
210 220
DQTKNFKRAL KNNFDKIVEQ SSKD
Length:224
Mass (Da):25,259
Last modified:October 31, 2012 - v1
Checksum:i8674C04BE5741FCC
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP003513 Genomic DNA. Translation: AFP81530.1.
RefSeqiWP_011113924.1. NC_018413.1.
YP_006586844.1. NC_018413.1.

Genome annotation databases

EnsemblBacteriaiAFP81530; AFP81530; HFMG08NCA_4952.
GeneIDi13466224.
KEGGimgan:HFMG08NCA_4952.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP003513 Genomic DNA. Translation: AFP81530.1 .
RefSeqi WP_011113924.1. NC_018413.1.
YP_006586844.1. NC_018413.1.

3D structure databases

ProteinModelPortali J7GUU3.
SMRi J7GUU3. Positions 12-212.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AFP81530 ; AFP81530 ; HFMG08NCA_4952 .
GeneIDi 13466224.
KEGGi mgan:HFMG08NCA_4952.

Phylogenomic databases

KOi K00857.

Family and domain databases

HAMAPi MF_00124. Thymidine_kinase.
InterProi IPR027417. P-loop_NTPase.
IPR001267. Thymidine_kinase.
IPR020633. Thymidine_kinase_CS.
IPR020634. Thymidine_kinase_subgr.
[Graphical view ]
PANTHERi PTHR11441. PTHR11441. 1 hit.
Pfami PF00265. TK. 1 hit.
[Graphical view ]
PIRSFi PIRSF035805. TK_cell. 1 hit.
SUPFAMi SSF52540. SSF52540. 1 hit.
PROSITEi PS00603. TK_CELLULAR_TYPE. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Extensive variation in surface lipoprotein gene content and genomic changes associated with virulence during evolution of a novel North American house finch epizootic strain of Mycoplasma gallisepticum."
    Tulman E.R., Liao X., Szczepanek S.M., Ley D.H., Kutish G.F., Geary S.J.
    Microbiology 158:2073-2088(2012) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: NC08_2008.031-4-3PImported.

Entry informationi

Entry nameiJ7GUU3_MYCGL
AccessioniPrimary (citable) accession number: J7GUU3
Entry historyi
Integrated into UniProtKB/TrEMBL: October 31, 2012
Last sequence update: October 31, 2012
Last modified: October 29, 2014
This is version 16 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

External Data

Dasty 3