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Protein

Thymidine kinase

Gene

BTF1_31242

Organism
Bacillus thuringiensis HD-789
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + thymidine = ADP + thymidine 5'-phosphate.UniRule annotation

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. thymidine kinase activity Source: UniProtKB-EC

GO - Biological processi

  1. DNA biosynthetic process Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

KinaseUniRule annotationImported, Transferase

Keywords - Biological processi

DNA synthesisUniRule annotation

Keywords - Ligandi

ATP-bindingUniRule annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Thymidine kinaseUniRule annotation (EC:2.7.1.21UniRule annotation)
Gene namesi
ORF Names:BTF1_31242Imported
Encoded oniPlasmid pBTHD789-2Imported
OrganismiBacillus thuringiensis HD-789Imported
Taxonomic identifieri1217737 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesBacillaceaeBacillusBacillus cereus group
ProteomesiUP000005257: Plasmid pBTHD789-2

Structurei

3D structure databases

ProteinModelPortaliJ4AC10.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the thymidine kinase family.UniRule annotation

Phylogenomic databases

KOiK00857.

Family and domain databases

Gene3Di3.40.50.300. 1 hit.
InterProiIPR027417. P-loop_NTPase.
IPR001267. Thymidine_kinase.
IPR020633. Thymidine_kinase_CS.
[Graphical view]
PANTHERiPTHR11441. PTHR11441. 1 hit.
PfamiPF00265. TK. 1 hit.
[Graphical view]
PIRSFiPIRSF035805. TK_cell. 1 hit.
SUPFAMiSSF52540. SSF52540. 1 hit.
PROSITEiPS00603. TK_CELLULAR_TYPE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

J4AC10-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MAKVVFYYGS MNSSKSAQLI MTAFNFEQQG KNFEIVKSSQ DTRDTKIKSR
60 70 80 90 100
ALSIEMDCTP ITHFTELIQI AMLKKPDWLF VDEVQFMDKD MIDTLSHLAD
110 120 130 140 150
DFGINVIAYG LMTDFQGQLF EGSKRLVESA DSIREIKNQC IHCENKANRN
160 170 180 190
VRLINNIPVF EGEVVQVGGN ESYSSVCRRC YNKIRRESKS TQKQ
Length:194
Mass (Da):22,245
Last modified:October 31, 2012 - v1
Checksum:iE82F10322FA812A9
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP003765 Genomic DNA. Translation: AFQ30348.1.
RefSeqiYP_006613834.1. NC_018509.1.

Genome annotation databases

EnsemblBacteriaiAFQ30348; AFQ30348; BTF1_31242.
GeneIDi13505362.
KEGGibtn:BTF1_31242.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP003765 Genomic DNA. Translation: AFQ30348.1.
RefSeqiYP_006613834.1. NC_018509.1.

3D structure databases

ProteinModelPortaliJ4AC10.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAFQ30348; AFQ30348; BTF1_31242.
GeneIDi13505362.
KEGGibtn:BTF1_31242.

Phylogenomic databases

KOiK00857.

Family and domain databases

Gene3Di3.40.50.300. 1 hit.
InterProiIPR027417. P-loop_NTPase.
IPR001267. Thymidine_kinase.
IPR020633. Thymidine_kinase_CS.
[Graphical view]
PANTHERiPTHR11441. PTHR11441. 1 hit.
PfamiPF00265. TK. 1 hit.
[Graphical view]
PIRSFiPIRSF035805. TK_cell. 1 hit.
SUPFAMiSSF52540. SSF52540. 1 hit.
PROSITEiPS00603. TK_CELLULAR_TYPE. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Complete Genome Sequence of Bacillus thuringiensis Serovar Israelensis Strain HD-789."
    Doggett N.A., Stubben C.J., Chertkov O., Bruce D.C., Detter J.C., Johnson S.L., Han C.S.
    Genome Announc. 1:e01023-13(2013) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: HD-789Imported.

Entry informationi

Entry nameiJ4AC10_BACTU
AccessioniPrimary (citable) accession number: J4AC10
Entry historyi
Integrated into UniProtKB/TrEMBL: October 31, 2012
Last sequence update: October 31, 2012
Last modified: February 4, 2015
This is version 19 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported, PlasmidImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.