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J3XA87

- J3XA87_LACHE

UniProt

J3XA87 - J3XA87_LACHE

Protein

Phosphoenolpyruvate carboxylase

Gene

ppc

Organism
Lactobacillus helveticus R0052
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 12 (01 Oct 2014)
      Sequence version 1 (31 Oct 2012)
      Previous versions | rss
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    Functioni

    Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.UniRule annotationSAAS annotation

    Catalytic activityi

    Phosphate + oxaloacetate = H2O + phosphoenolpyruvate + HCO3-.UniRule annotationSAAS annotation

    Cofactori

    Magnesium.UniRule annotationSAAS annotation

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei138 – 1381UniRule annotation
    Active sitei575 – 5751UniRule annotation

    GO - Molecular functioni

    1. magnesium ion binding Source: UniProtKB-HAMAP
    2. phosphoenolpyruvate carboxylase activity Source: UniProtKB-HAMAP

    GO - Biological processi

    1. carbon fixation Source: UniProtKB-HAMAP
    2. oxaloacetate metabolic process Source: UniProtKB-HAMAP
    3. tricarboxylic acid cycle Source: InterPro

    Keywords - Molecular functioni

    LyaseUniRule annotationSAAS annotationImported

    Keywords - Biological processi

    Carbon dioxide fixationUniRule annotationSAAS annotation

    Keywords - Ligandi

    MagnesiumUniRule annotationSAAS annotation, PyruvateImported

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Phosphoenolpyruvate carboxylaseUniRule annotation (EC:4.1.1.31UniRule annotation)
    Short name:
    PEPCUniRule annotation
    Short name:
    PEPCaseUniRule annotation
    Gene namesi
    Name:ppcUniRule annotation
    ORF Names:R0052_05745Imported
    OrganismiLactobacillus helveticus R0052Imported
    Taxonomic identifieri880633 [NCBI]
    Taxonomic lineageiBacteriaFirmicutesBacilliLactobacillalesLactobacillaceaeLactobacillus
    ProteomesiUP000003775: Chromosome

    Interactioni

    Subunit structurei

    Homotetramer.UniRule annotation

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the PEPCase type 1 family.UniRule annotation

    Phylogenomic databases

    KOiK01595.

    Family and domain databases

    HAMAPiMF_00595. PEPcase_type1.
    InterProiIPR021135. PEP_COase.
    IPR018129. PEP_COase_AS.
    IPR022805. PEP_COase_bac/pln-type.
    IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
    [Graphical view]
    PfamiPF00311. PEPcase. 1 hit.
    [Graphical view]
    PRINTSiPR00150. PEPCARBXLASE.
    SUPFAMiSSF51621. SSF51621. 1 hit.
    PROSITEiPS00781. PEPCASE_1. 1 hit.
    PS00393. PEPCASE_2. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    J3XA87-1 [UniParc]FASTAAdd to Basket

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    MTVKKLENSS DVNVVTEEVK ILTNLLNEST EQLIGKELFT KIQNLIKISA    50
    NKNYQELEDQ IASLDNREMI VVARYFATLP LLINISEDVE LASKVNVLNN 100
    TNQDYLGKLN DTIDIVAQKK NAKEILEKVS VVPVLTAHPT QVQRKTVLEL 150
    TDKIHKLLRN YREVKNGIIN REEWTEELRA CIEILMQTDI IRGHKLKVSN 200
    EITNALTYYP KSLIPAITKF TARYKELAKK HGLDIPDATP ITMGMWIGGD 250
    RDGNPYVTAD TLKLSATLQG QVIFEYYIKQ INQLYRSISL STSYMKPSTE 300
    VMHLSELSND DSPFRTNEPY RRAFYYIESR LVRSEQKLLN ITNQHSFLKE 350
    RDVEHLDQIP AYENAQEFKA DLEIIKRSLE ENRDQAVVKS YFTEILEAID 400
    VFGFHLATID MRQDSSVNEA CVAELLKSAE ICDHYSDLSE KEKVSLLLNE 450
    LNNDPRNLHA NNKPKSELLQ KELKIYKTAR DLKDRLGEDV IKQHIISHTE 500
    SVSDMLEQAI MLKEYDLLDN QSARVQVVPL FETVEDLNNA RDIIKEYLNL 550
    DIVKKWLVSQ HNYQEVMLGY SDSNKDGGYL ASCWNLYKAQ KDLTAIGEEL 600
    GIKITYMHGR GGTVGRGGGP SYEAITAQPF NSINDRIRMT EQGEIIQNKY 650
    GNKDAAYYNL EMLVSATVDR IASKQIVSEE YIADFRSSMD EIVTESNEIY 700
    KKLVFENPNF LDYFLQATPI KEISNLNIGS RPASRKKLSD FSSLRAIPWV 750
    FSWSQSRVMF PAWYGVGSAF KHFIDADKNN LQELQHMYQG WPFFHALLSN 800
    VDMVLSKSNM EIAKQYAELC QDEKTKSVFD IIYQEWKLTK QIILQIEGHD 850
    DLLSDAPNLK NSLAARMPYF NILNYIQLEM IKRDREDEIQ GVFQSIIPIT 900
    INGVASGLRN SG 912
    Length:912
    Mass (Da):104,589
    Last modified:October 31, 2012 - v1
    Checksum:iE2546EB845990E17
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP003799 Genomic DNA. Translation: AFR22004.1.
    RefSeqiYP_006655808.1. NC_018528.1.

    Genome annotation databases

    EnsemblBacteriaiAFR22004; AFR22004; R0052_05745.
    GeneIDi13554842.
    KEGGilhr:R0052_05745.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP003799 Genomic DNA. Translation: AFR22004.1 .
    RefSeqi YP_006655808.1. NC_018528.1.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AFR22004 ; AFR22004 ; R0052_05745 .
    GeneIDi 13554842.
    KEGGi lhr:R0052_05745.

    Phylogenomic databases

    KOi K01595.

    Family and domain databases

    HAMAPi MF_00595. PEPcase_type1.
    InterProi IPR021135. PEP_COase.
    IPR018129. PEP_COase_AS.
    IPR022805. PEP_COase_bac/pln-type.
    IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
    [Graphical view ]
    Pfami PF00311. PEPcase. 1 hit.
    [Graphical view ]
    PRINTSi PR00150. PEPCARBXLASE.
    SUPFAMi SSF51621. SSF51621. 1 hit.
    PROSITEi PS00781. PEPCASE_1. 1 hit.
    PS00393. PEPCASE_2. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Complete Genome Sequence of Lactobacillus helveticus R0052, a Commercial Probiotic Strain."
      Tompkins T.A., Barreau G., Broadbent J.R.
      J. Bacteriol. 194:6349-6349(2012) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: R0052Imported.

    Entry informationi

    Entry nameiJ3XA87_LACHE
    AccessioniPrimary (citable) accession number: J3XA87
    Entry historyi
    Integrated into UniProtKB/TrEMBL: October 31, 2012
    Last sequence update: October 31, 2012
    Last modified: October 1, 2014
    This is version 12 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteomeImported

    External Data

    Dasty 3