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J3XA87

- J3XA87_LACHE

UniProt

J3XA87 - J3XA87_LACHE

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Protein

Phosphoenolpyruvate carboxylase

Gene

ppc

Organism
Lactobacillus helveticus R0052
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.UniRule annotationSAAS annotation

Catalytic activityi

Phosphate + oxaloacetate = H2O + phosphoenolpyruvate + HCO3-.UniRule annotationSAAS annotation

Cofactori

Note: Magnesium.UniRule annotationSAAS annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei138 – 1381UniRule annotation
Active sitei575 – 5751UniRule annotation

GO - Molecular functioni

  1. magnesium ion binding Source: UniProtKB-HAMAP
  2. phosphoenolpyruvate carboxylase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. carbon fixation Source: UniProtKB-HAMAP
  2. oxaloacetate metabolic process Source: UniProtKB-HAMAP
  3. tricarboxylic acid cycle Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

LyaseUniRule annotationSAAS annotation

Keywords - Biological processi

Carbon dioxide fixationUniRule annotationSAAS annotation

Keywords - Ligandi

MagnesiumUniRule annotationSAAS annotation, PyruvateImported

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoenolpyruvate carboxylaseUniRule annotation (EC:4.1.1.31UniRule annotation)
Short name:
PEPCUniRule annotation
Short name:
PEPCaseUniRule annotation
Gene namesi
Name:ppcUniRule annotation
ORF Names:R0052_05745Imported
OrganismiLactobacillus helveticus R0052Imported
Taxonomic identifieri880633 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliLactobacillalesLactobacillaceaeLactobacillus
ProteomesiUP000003775: Chromosome

Interactioni

Subunit structurei

Homotetramer.UniRule annotation

Family & Domainsi

Sequence similaritiesi

Belongs to the PEPCase type 1 family.UniRule annotation

Phylogenomic databases

KOiK01595.

Family and domain databases

HAMAPiMF_00595. PEPcase_type1.
InterProiIPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view]
PfamiPF00311. PEPcase. 1 hit.
[Graphical view]
PRINTSiPR00150. PEPCARBXLASE.
SUPFAMiSSF51621. SSF51621. 1 hit.
PROSITEiPS00781. PEPCASE_1. 1 hit.
PS00393. PEPCASE_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

J3XA87-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MTVKKLENSS DVNVVTEEVK ILTNLLNEST EQLIGKELFT KIQNLIKISA
60 70 80 90 100
NKNYQELEDQ IASLDNREMI VVARYFATLP LLINISEDVE LASKVNVLNN
110 120 130 140 150
TNQDYLGKLN DTIDIVAQKK NAKEILEKVS VVPVLTAHPT QVQRKTVLEL
160 170 180 190 200
TDKIHKLLRN YREVKNGIIN REEWTEELRA CIEILMQTDI IRGHKLKVSN
210 220 230 240 250
EITNALTYYP KSLIPAITKF TARYKELAKK HGLDIPDATP ITMGMWIGGD
260 270 280 290 300
RDGNPYVTAD TLKLSATLQG QVIFEYYIKQ INQLYRSISL STSYMKPSTE
310 320 330 340 350
VMHLSELSND DSPFRTNEPY RRAFYYIESR LVRSEQKLLN ITNQHSFLKE
360 370 380 390 400
RDVEHLDQIP AYENAQEFKA DLEIIKRSLE ENRDQAVVKS YFTEILEAID
410 420 430 440 450
VFGFHLATID MRQDSSVNEA CVAELLKSAE ICDHYSDLSE KEKVSLLLNE
460 470 480 490 500
LNNDPRNLHA NNKPKSELLQ KELKIYKTAR DLKDRLGEDV IKQHIISHTE
510 520 530 540 550
SVSDMLEQAI MLKEYDLLDN QSARVQVVPL FETVEDLNNA RDIIKEYLNL
560 570 580 590 600
DIVKKWLVSQ HNYQEVMLGY SDSNKDGGYL ASCWNLYKAQ KDLTAIGEEL
610 620 630 640 650
GIKITYMHGR GGTVGRGGGP SYEAITAQPF NSINDRIRMT EQGEIIQNKY
660 670 680 690 700
GNKDAAYYNL EMLVSATVDR IASKQIVSEE YIADFRSSMD EIVTESNEIY
710 720 730 740 750
KKLVFENPNF LDYFLQATPI KEISNLNIGS RPASRKKLSD FSSLRAIPWV
760 770 780 790 800
FSWSQSRVMF PAWYGVGSAF KHFIDADKNN LQELQHMYQG WPFFHALLSN
810 820 830 840 850
VDMVLSKSNM EIAKQYAELC QDEKTKSVFD IIYQEWKLTK QIILQIEGHD
860 870 880 890 900
DLLSDAPNLK NSLAARMPYF NILNYIQLEM IKRDREDEIQ GVFQSIIPIT
910
INGVASGLRN SG
Length:912
Mass (Da):104,589
Last modified:October 31, 2012 - v1
Checksum:iE2546EB845990E17
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP003799 Genomic DNA. Translation: AFR22004.1.
RefSeqiYP_006655808.1. NC_018528.1.

Genome annotation databases

EnsemblBacteriaiAFR22004; AFR22004; R0052_05745.
GeneIDi13554842.
KEGGilhr:R0052_05745.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP003799 Genomic DNA. Translation: AFR22004.1 .
RefSeqi YP_006655808.1. NC_018528.1.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AFR22004 ; AFR22004 ; R0052_05745 .
GeneIDi 13554842.
KEGGi lhr:R0052_05745.

Phylogenomic databases

KOi K01595.

Family and domain databases

HAMAPi MF_00595. PEPcase_type1.
InterProi IPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view ]
Pfami PF00311. PEPcase. 1 hit.
[Graphical view ]
PRINTSi PR00150. PEPCARBXLASE.
SUPFAMi SSF51621. SSF51621. 1 hit.
PROSITEi PS00781. PEPCASE_1. 1 hit.
PS00393. PEPCASE_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Complete Genome Sequence of Lactobacillus helveticus R0052, a Commercial Probiotic Strain."
    Tompkins T.A., Barreau G., Broadbent J.R.
    J. Bacteriol. 194:6349-6349(2012) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: R0052Imported.

Entry informationi

Entry nameiJ3XA87_LACHE
AccessioniPrimary (citable) accession number: J3XA87
Entry historyi
Integrated into UniProtKB/TrEMBL: October 31, 2012
Last sequence update: October 31, 2012
Last modified: November 26, 2014
This is version 14 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

External Data

Dasty 3