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J3XA87

- J3XA87_LACHE

UniProt

J3XA87 - J3XA87_LACHE

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Protein

Phosphoenolpyruvate carboxylase

Gene
ppc, R0052_05745
Organism
Lactobacillus helveticus R0052
Status
Unreviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle By similarity.UniRule annotationSAAS annotations

Catalytic activityi

Phosphate + oxaloacetate = H2O + phosphoenolpyruvate + HCO3-.UniRule annotationSAAS annotations

Cofactori

Magnesium By similarity.UniRule annotationSAAS annotations

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei138 – 1381 By similarityUniRule annotation
Active sitei575 – 5751 By similarityUniRule annotation

GO - Molecular functioni

  1. magnesium ion binding Source: UniProtKB-HAMAP
  2. phosphoenolpyruvate carboxylase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. carbon fixation Source: UniProtKB-HAMAP
  2. oxaloacetate metabolic process Source: UniProtKB-HAMAP
  3. tricarboxylic acid cycle Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

LyaseUniRule annotationSAAS annotationsImported

Keywords - Biological processi

Carbon dioxide fixationUniRule annotationSAAS annotations

Keywords - Ligandi

MagnesiumUniRule annotationSAAS annotations, PyruvateImported

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoenolpyruvate carboxylaseUniRule annotation (EC:4.1.1.31UniRule annotation)
Short name:
PEPCUniRule annotation
Short name:
PEPCaseUniRule annotation
Gene namesi
Name:ppcUniRule annotation
ORF Names:R0052_05745Imported
OrganismiLactobacillus helveticus R0052Imported
Taxonomic identifieri880633 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliLactobacillalesLactobacillaceaeLactobacillus
ProteomesiUP000003775: Chromosome

Interactioni

Subunit structurei

Homotetramer By similarity.UniRule annotation

Family & Domainsi

Sequence similaritiesi

Belongs to the PEPCase type 1 family.UniRule annotation

Phylogenomic databases

KOiK01595.

Family and domain databases

HAMAPiMF_00595. PEPcase_type1.
InterProiIPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view]
PfamiPF00311. PEPcase. 1 hit.
[Graphical view]
PRINTSiPR00150. PEPCARBXLASE.
SUPFAMiSSF51621. SSF51621. 1 hit.
PROSITEiPS00781. PEPCASE_1. 1 hit.
PS00393. PEPCASE_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

J3XA87-1 [UniParc]FASTAAdd to Basket

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MTVKKLENSS DVNVVTEEVK ILTNLLNEST EQLIGKELFT KIQNLIKISA    50
NKNYQELEDQ IASLDNREMI VVARYFATLP LLINISEDVE LASKVNVLNN 100
TNQDYLGKLN DTIDIVAQKK NAKEILEKVS VVPVLTAHPT QVQRKTVLEL 150
TDKIHKLLRN YREVKNGIIN REEWTEELRA CIEILMQTDI IRGHKLKVSN 200
EITNALTYYP KSLIPAITKF TARYKELAKK HGLDIPDATP ITMGMWIGGD 250
RDGNPYVTAD TLKLSATLQG QVIFEYYIKQ INQLYRSISL STSYMKPSTE 300
VMHLSELSND DSPFRTNEPY RRAFYYIESR LVRSEQKLLN ITNQHSFLKE 350
RDVEHLDQIP AYENAQEFKA DLEIIKRSLE ENRDQAVVKS YFTEILEAID 400
VFGFHLATID MRQDSSVNEA CVAELLKSAE ICDHYSDLSE KEKVSLLLNE 450
LNNDPRNLHA NNKPKSELLQ KELKIYKTAR DLKDRLGEDV IKQHIISHTE 500
SVSDMLEQAI MLKEYDLLDN QSARVQVVPL FETVEDLNNA RDIIKEYLNL 550
DIVKKWLVSQ HNYQEVMLGY SDSNKDGGYL ASCWNLYKAQ KDLTAIGEEL 600
GIKITYMHGR GGTVGRGGGP SYEAITAQPF NSINDRIRMT EQGEIIQNKY 650
GNKDAAYYNL EMLVSATVDR IASKQIVSEE YIADFRSSMD EIVTESNEIY 700
KKLVFENPNF LDYFLQATPI KEISNLNIGS RPASRKKLSD FSSLRAIPWV 750
FSWSQSRVMF PAWYGVGSAF KHFIDADKNN LQELQHMYQG WPFFHALLSN 800
VDMVLSKSNM EIAKQYAELC QDEKTKSVFD IIYQEWKLTK QIILQIEGHD 850
DLLSDAPNLK NSLAARMPYF NILNYIQLEM IKRDREDEIQ GVFQSIIPIT 900
INGVASGLRN SG 912
Length:912
Mass (Da):104,589
Last modified:October 31, 2012 - v1
Checksum:iE2546EB845990E17
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP003799 Genomic DNA. Translation: AFR22004.1.
RefSeqiYP_006655808.1. NC_018528.1.

Genome annotation databases

EnsemblBacteriaiAFR22004; AFR22004; R0052_05745.
GeneIDi13554842.
KEGGilhr:R0052_05745.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP003799 Genomic DNA. Translation: AFR22004.1 .
RefSeqi YP_006655808.1. NC_018528.1.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AFR22004 ; AFR22004 ; R0052_05745 .
GeneIDi 13554842.
KEGGi lhr:R0052_05745.

Phylogenomic databases

KOi K01595.

Family and domain databases

HAMAPi MF_00595. PEPcase_type1.
InterProi IPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view ]
Pfami PF00311. PEPcase. 1 hit.
[Graphical view ]
PRINTSi PR00150. PEPCARBXLASE.
SUPFAMi SSF51621. SSF51621. 1 hit.
PROSITEi PS00781. PEPCASE_1. 1 hit.
PS00393. PEPCASE_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Complete Genome Sequence of Lactobacillus helveticus R0052, a Commercial Probiotic Strain."
    Tompkins T.A., Barreau G., Broadbent J.R.
    J. Bacteriol. 194:6349-6349(2012) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: R0052Imported.

Entry informationi

Entry nameiJ3XA87_LACHE
AccessioniPrimary (citable) accession number: J3XA87
Entry historyi
Integrated into UniProtKB/TrEMBL: October 31, 2012
Last sequence update: October 31, 2012
Last modified: September 3, 2014
This is version 11 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome

External Data

Dasty 3

Similar proteinsi